Avermectin is a lipid of Polyketides (PK) class. Avermectin is associated with abnormalities such as Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease and Onchocerciasis. The involved functions are known as Anabolism, Binding (Molecular Function), physiological aspects, Saturated and Cell Growth. Avermectin often locates in receptor complex and cell body (neuron). The associated genes with Avermectin are Homologous Gene, Genome, Gene Clusters and Structural gene.
To understand associated biological information of Avermectin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Avermectin is suspected in Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease, Onchocerciasis, Filarial Elephantiases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Avermectin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Oesophagostomiasis | D009814 | 2 associated lipids |
| Filariasis | D005368 | 6 associated lipids |
| Arteritis | D001167 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen TS et al. | Directed biosynthesis of avermectins. | 1989 | Arch. Biochem. Biophys. | pmid:2919882 |
| Boukhrissa A et al. | Study of the degradation in aqueous solution of a refractory organic compound: avermectin type used as pesticide in agriculture. | 2017 | Water Sci. Technol. | pmid:29068328 |
| Gao Q et al. | Learn from microbial intelligence for avermectins overproduction. | 2017 | Curr. Opin. Biotechnol. | pmid:29049952 |
| Pampiglione S et al. | [Evaluation of the biological activity of avermectin against mosquitoes]. | 1986 | Ann. Ist. Super. Sanita | pmid:2875685 |
| Mermans C et al. | A G326E substitution in the glutamate-gated chloride channel 3 (GluCl3) of the two-spotted spider mite Tetranychus urticae abolishes the agonistic activity of macrocyclic lactones. | 2017 | Pest Manag. Sci. | pmid:28736919 |
| Suroto DA et al. | Activation of cryptic phthoxazolin A production in Streptomyces avermitilis by the disruption of autoregulator-receptor homologue AvaR3. | 2017 | J. Biosci. Bioeng. | pmid:28728974 |
| Liang J et al. | Bioinspired Development of P(St-MAA)-Avermectin Nanoparticles with High Affinity for Foliage To Enhance Folia Retention. | 2018 | J. Agric. Food Chem. | pmid:28727420 |
| Guan W et al. | Fabrication of Novel Avermectin Nanoemulsion Using a Polyurethane Emulsifier with Cleavable Disulfide Bonds. | 2018 | J. Agric. Food Chem. | pmid:28700229 |
| Cui Q et al. | Avermectin biosynthesis: stable functional expression of branched chain α-keto acid dehydrogenase complex from Streptomyces avermitilis in Escherichia coli by selectively regulating individual subunit gene expression. | 2017 | Biotechnol. Lett. | pmid:28664314 |
| Zhang W et al. | Determination of avermectins by the internal standard recovery correction - high performance liquid chromatography - quantitative Nuclear Magnetic Resonance method. | 2017 | Talanta | pmid:28602306 |