Avermectin is a lipid of Polyketides (PK) class. Avermectin is associated with abnormalities such as Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease and Onchocerciasis. The involved functions are known as Anabolism, Binding (Molecular Function), physiological aspects, Saturated and Cell Growth. Avermectin often locates in receptor complex and cell body (neuron). The associated genes with Avermectin are Homologous Gene, Genome, Gene Clusters and Structural gene.
To understand associated biological information of Avermectin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Avermectin is suspected in Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease, Onchocerciasis, Filarial Elephantiases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Avermectin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Oesophagostomiasis | D009814 | 2 associated lipids |
| Filariasis | D005368 | 6 associated lipids |
| Arteritis | D001167 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhao X et al. | Pesticide-mediated interspecific competition between local and invasive thrips pests. | 2017 | Sci Rep | pmid:28084404 |
| Neszmélyi A et al. | Solution conformation of the disaccharide of avermectin B1a examined by NMR spectroscopy and nuclear Overhauser enhancement restrained hard-sphere exo-anomeric effect calculation. | 1989 | J. Antibiot. | pmid:2808137 |
| Maynard MS and Maynard HD | HPLC assay for avermectin B1a and its two photoisomers using a photo diode array detector. | 1989 | Bull Environ Contam Toxicol | pmid:2804390 |
| Liu C et al. | Avermectin induced global DNA hypomethylation and over-expression of heat shock proteins in cardiac tissues of pigeon. | 2017 | Pestic Biochem Physiol | pmid:28043331 |
| Tian P et al. | Comparative metabolomics reveals the mechanism of avermectin production enhancement by S-adenosylmethionine. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:27988821 |
| Mendes AM et al. | Inhibition of Plasmodium Liver Infection by Ivermectin. | 2017 | Antimicrob. Agents Chemother. | pmid:27895022 |
| Iwai Y | Anecdote of the ÅŒmura laboratory and the discovery of avermectin. | 2017 | Biosci. Biotechnol. Biochem. | pmid:27885935 |
| Takahashi Y | Continuing fascination of exploration in natural substances from microorganisms. | 2017 | Biosci. Biotechnol. Biochem. | pmid:27885930 |
| Hotta K | Epoch-making milestones in antibiotic exploratory researches in Japan. | 2017 | Biosci. Biotechnol. Biochem. | pmid:27885928 |
| He JM et al. | Direct Involvement of the Master Nitrogen Metabolism Regulator GlnR in Antibiotic Biosynthesis in Streptomyces. | 2016 | J. Biol. Chem. | pmid:27875313 |