Avermectin is a lipid of Polyketides (PK) class. Avermectin is associated with abnormalities such as Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease and Onchocerciasis. The involved functions are known as Anabolism, Binding (Molecular Function), physiological aspects, Saturated and Cell Growth. Avermectin often locates in receptor complex and cell body (neuron). The associated genes with Avermectin are Homologous Gene, Genome, Gene Clusters and Structural gene.
To understand associated biological information of Avermectin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Avermectin is suspected in Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease, Onchocerciasis, Filarial Elephantiases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Avermectin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Arteritis | D001167 | 2 associated lipids |
| Filariasis | D005368 | 6 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Oesophagostomiasis | D009814 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Suroto DA et al. | Activation of cryptic phthoxazolin A production in Streptomyces avermitilis by the disruption of autoregulator-receptor homologue AvaR3. | 2017 | J. Biosci. Bioeng. | pmid:28728974 |
| Wang YS et al. | A spectrophotometric screening method for avermectin oxidizing microorganisms. | 2017 | J. Microbiol. Methods | pmid:28215961 |
| Chen LP et al. | Direct interaction of avermectin with epidermal growth factor receptor mediates the penetration resistance in Drosophila larvae. | 2016 | Open Biol | pmid:27249340 |
| Li Y et al. | Preparation, Characterization, and Insecticidal Activity of Avermectin-Grafted-Carboxymethyl Chitosan. | 2016 | Biomed Res Int | pmid:27213156 |
| Sultan SP et al. | Characterization of AvaR1, a butenolide-autoregulator receptor for biosynthesis of a Streptomyces hormone in Streptomyces avermitilis. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27541747 |
| He JM et al. | Direct Involvement of the Master Nitrogen Metabolism Regulator GlnR in Antibiotic Biosynthesis in Streptomyces. | 2016 | J. Biol. Chem. | pmid:27875313 |
| Zhao Y et al. | Isolation, characterization, and tissue-specific expression of GABA A receptor α1 subunit gene of Carassius auratus gibelio after avermectin treatment. | 2016 | Fish Physiol. Biochem. | pmid:26318443 |
| Kose LP et al. | The effects of some avermectins on bovine carbonic anhydrase enzyme. | 2016 | J Enzyme Inhib Med Chem | pmid:26207514 |
| Hopwood DA | Satoshi ÅŒmura. | 2016 | J. Ind. Microbiol. Biotechnol. | pmid:26186906 |
| Wenjie W et al. | Nystagmus following acute avermectins poisoning. | 2016 | Toxicol Ind Health | pmid:24280654 |