Avermectin is a lipid of Polyketides (PK) class. Avermectin is associated with abnormalities such as Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease and Onchocerciasis. The involved functions are known as Anabolism, Binding (Molecular Function), physiological aspects, Saturated and Cell Growth. Avermectin often locates in receptor complex and cell body (neuron). The associated genes with Avermectin are Homologous Gene, Genome, Gene Clusters and Structural gene.
To understand associated biological information of Avermectin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Avermectin is suspected in Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease, Onchocerciasis, Filarial Elephantiases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Avermectin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Arteritis | D001167 | 2 associated lipids |
| Filariasis | D005368 | 6 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Oesophagostomiasis | D009814 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Molento MB et al. | Resistance to avermectin/milbemycin anthelmintics in equine cyathostomins - current situation. | 2012 | Vet. Parasitol. | pmid:22047763 |
| Shoop WL et al. | Structure and activity of avermectins and milbemycins in animal health. | 1995 | Vet. Parasitol. | pmid:7483237 |
| Orpin P | Potential avermectin resistance in a cattle herd. | 2010 | Vet. Rec. | pmid:20622213 |
| Sargison ND et al. | Characterisation of milbemycin-, avermectin-, imidazothiazole- and benzimidazole-resistant Teladorsagia circumcincta from a sheep flock. | 2010 | Vet. Rec. | pmid:20511651 |
| Hoste H et al. | A questionnaire survey on the practices adopted to control gastrointestinal nematode parasitism in dairy goat farms in France. | 2000 | Vet. Res. Commun. | pmid:11085466 |
| Campbell WC | Efficacy of the avermectins against filarial parasites: a short review. | 1982 | Vet. Res. Commun. | pmid:7051527 |
| Brayden DJ and Griffin J | Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers. | 2008 | Vet. Res. Commun. | pmid:17578674 |
| Boukhrissa A et al. | Study of the degradation in aqueous solution of a refractory organic compound: avermectin type used as pesticide in agriculture. | 2017 | Water Sci. Technol. | pmid:29068328 |
| Zhao X et al. | Overexpression of metK shows different effects on avermectin production in various Streptomyces avermitilis strains. | 2013 | World J. Microbiol. Biotechnol. | pmid:23579768 |
| Sun Y et al. | [Effects of avermectin B1a on soil microorganism and earthworm (Eisenia fetida)]. | 2005 | Ying Yong Sheng Tai Xue Bao | pmid:16471355 |