Avermectin is a lipid of Polyketides (PK) class. Avermectin is associated with abnormalities such as Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease and Onchocerciasis. The involved functions are known as Anabolism, Binding (Molecular Function), physiological aspects, Saturated and Cell Growth. Avermectin often locates in receptor complex and cell body (neuron). The associated genes with Avermectin are Homologous Gene, Genome, Gene Clusters and Structural gene.
To understand associated biological information of Avermectin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Avermectin is suspected in Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease, Onchocerciasis, Filarial Elephantiases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Avermectin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Arteritis | D001167 | 2 associated lipids |
| Filariasis | D005368 | 6 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Oesophagostomiasis | D009814 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lofgren CS and Williams DF | Avermectin B1a: highly potent inhibitor of reproduction by queens of the red imported fire ant (Hymenoptera: Formicidae). | 1982 | J. Econ. Entomol. | pmid:7175003 |
| Williams M and Risley EA | Interaction of avermectins with [3H]beta-carboline-3-carboxylate ethyl ester and [3H]diazepam binding sites in rat brain cortical membranes. | 1982 | Eur. J. Pharmacol. | pmid:6277673 |
| Sano M et al. | Effects of avermectin B1a on the motility of various parasitic helminths. | 1981 | Experientia | pmid:7286134 |
| Drummond RO et al. | Control of ticks systemically with Merck MK-933, an avermectin. | 1981 | J. Econ. Entomol. | pmid:7320317 |
| Yazwinski TA et al. | The effectiveness of ivermectin for reducing bovine gastrointestinal helminthiasis. | 1981 | Vet Med Small Anim Clin | pmid:6911919 |
| Campbell WC | An introduction to the avermectins. | 1981 | N Z Vet J | pmid:7038568 |
| Paul SM et al. | Avermectin B1a: an irreversible activator of the gamma-aminobutyric acid-benzodiazepine-chloride-ionophore receptor complex. | 1980 | Biochem. Biophys. Res. Commun. | pmid:6252889 |
| Slocombe JO and McCraw BM | Evaluation of pyrantel pamoate, nitramisole and avermectin B1a against migrating Strongylus vulgaris larvae. | 1980 | Can. J. Comp. Med. | pmid:7397601 |
| Wescott RB et al. | Efficacy of avermectin B1a for treatment of experimentally induced nematode infections in cattle. | 1980 | Am. J. Vet. Res. | pmid:6449894 |
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