Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Parasitic Diseases, Animal D010273 1 associated lipids
Larva Migrans D007815 1 associated lipids
Ectoparasitic Infestations D004478 2 associated lipids
Scabies D012532 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Fish Diseases D005393 5 associated lipids
Dog Diseases D004283 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Trichostrongylosis D014253 5 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Authors Title Published Journal PubMed Link
Li M et al. Exploring the electron transfer pathway in the oxidation of avermectin by CYP107Z13 in Streptomyces ahygroscopicus ZB01. 2014 PLoS ONE pmid:24905717
Huang WK et al. Efficacy evaluation of fungus Syncephalastrum racemosum and nematicide avermectin against the root-knot nematode Meloidogyne incognita on cucumber. 2014 PLoS ONE pmid:24586982
Liu M et al. Magnetic field is the dominant factor to induce the response of Streptomyces avermitilis in altered gravity simulated by diamagnetic levitation. 2011 PLoS ONE pmid:22039402
Gao Y et al. Insecticide-mediated apparent displacement between two invasive species of leafminer fly. 2012 PLoS ONE pmid:22662122
Omansen TF et al. In-vitro activity of avermectins against Mycobacterium ulcerans. 2015 PLoS Negl Trop Dis pmid:25742173
Efferth T et al. Nobel Prize for artemisinin brings phytotherapy into the spotlight. 2015 Phytomedicine pmid:26563851
Roos MH et al. Molecular aspects of drug resistance in parasitic helminths. 1993 Pharmacol. Ther. pmid:8022863
Liu C et al. Avermectin induced global DNA hypomethylation and over-expression of heat shock proteins in cardiac tissues of pigeon. 2017 Pestic Biochem Physiol pmid:28043331
Chen LJ et al. The effects of avermectin on amino acid neurotransmitters and their receptors in the pigeon brain. 2014 Pestic Biochem Physiol pmid:24759046
Li HB et al. Combined effects of temperature and avermectins on life history and stress response of the western flower thrips, Frankliniella occidentalis. 2014 Pestic Biochem Physiol pmid:24485314