Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Larva Migrans D007815 1 associated lipids
Parasitic Diseases, Animal D010273 1 associated lipids
Scabies D012532 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Ectoparasitic Infestations D004478 2 associated lipids
Dog Diseases D004283 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Trichostrongylosis D014253 5 associated lipids
Fish Diseases D005393 5 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Authors Title Published Journal PubMed Link
Gill JH and Redwin JM Cryopreservation of the first-stage larvae of trichostrongylid nematode parasites. 1995 Int. J. Parasitol. pmid:8719953
Herd R Ecotoxicity of the avermectins: a reply to Forbes. 1996 Int. J. Parasitol. pmid:8818740
Venkatachalam MA et al. Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels. 1996 Kidney Int. pmid:8821829
Titchener RN and Purnell RE Duration of persistence of injectable avermectins against sucking lice of cattle. 1996 Vet. Rec. pmid:8903014
McKellar QA and Benchaoui HA Avermectins and milbemycins. 1996 J. Vet. Pharmacol. Ther. pmid:8905567
Shoop WL et al. Efficacy in sheep and pharmacokinetics in cattle that led to the selection of eprinomectin as a topical endectocide for cattle. 1996 Int. J. Parasitol. pmid:9024866
Shoop WL et al. Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. 1996 Int. J. Parasitol. pmid:9024867
Krieger RI et al. Adult and infant abamectin exposures following Avert 310 and pressurized gel crack and crevice treatment. 1997 Bull Environ Contam Toxicol pmid:9115128
Vassilatis DK et al. Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels. 1997 J. Mol. Evol. pmid:9115174
Gray AK Avermectin toxicity in the dog. 1997 Vet. Rec. pmid:9185316