Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Parasitic Diseases, Animal D010273 1 associated lipids
Larva Migrans D007815 1 associated lipids
Ectoparasitic Infestations D004478 2 associated lipids
Scabies D012532 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Fish Diseases D005393 5 associated lipids
Dog Diseases D004283 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Trichostrongylosis D014253 5 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Authors Title Published Journal PubMed Link
Merola VM and Eubig PA Toxicology of Avermectins and Milbemycins (Macrocyclic Lactones) and the Role of P-Glycoprotein in Dogs and Cats. 2018 Vet. Clin. North Am. Small Anim. Pract. pmid:30139545
Merola VM and Eubig PA Toxicology of avermectins and milbemycins (macrocylic lactones) and the role of P-glycoprotein in dogs and cats. 2012 Vet. Clin. North Am. Small Anim. Pract. pmid:22381182
Bowen JM The avermectin complex: a new horizon in anthelmintic therapy. 1981 Vet Med Small Anim Clin pmid:6908751
Vercruysse J and Claerebout E Effect of chemoprophylaxis on immunity to gastrointestinal nematodes in cattle. 1996 Verh. K. Acad. Geneeskd. Belg. pmid:8701602
Mandzynets SM et al. [Avermectin effects on ultrastructure characteristics of the loach embryos]. 2011 Sep-Oct Tsitol. Genet. pmid:22168050
Swarnkar CP et al. Anthelmintic resistance on an organized sheep farm in India. 2001 Trop Anim Health Prod pmid:11474864
Hassan MU et al. Bovine hypodermosis--a global aspect. 2010 Trop Anim Health Prod pmid:20607401
Molyneux DH and Ward SA Reflections on the Nobel Prize for Medicine 2015--The Public Health Legacy and Impact of Avermectin and Artemisinin. 2015 Trends Parasitol. pmid:26552892
Goodwin LG Recent advances in research on filariasis. Chemotherapy. 1984 Trans. R. Soc. Trop. Med. Hyg. pmid:6382706
Xu Z et al. From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. 2017 Toxicol. Sci. pmid:27742867