| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dog Diseases | D004283 | 5 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Poisoning | D011041 | 9 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
| Fish Diseases | D005393 | 5 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Ostertagiasis | D010029 | 2 associated lipids |
| Strongylida Infections | D017206 | 5 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Lice Infestations | D010373 | 9 associated lipids |
| Ectoparasitic Infestations | D004478 | 2 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Parasitic Diseases, Animal | D010273 | 1 associated lipids |
| Scabies | D012532 | 2 associated lipids |
| Larva Migrans | D007815 | 1 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Proc. Natl. Acad. Sci. U.S.A. (1)
- Stem Cell Reports (1)
- Antimicrob. Agents Chemother. (1)
- Others (3)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
- Proc. Natl. Acad. Sci. U.S.A. (3)
- Appl. Environ. Microbiol. (3)
- Microbiology (Reading, Engl.) (1)
- Others (5)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
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| Zhang H et al. | Preparation and Characterization of Controlled-Release Avermectin/Castor Oil-Based Polyurethane Nanoemulsions. | 2018 | J. Agric. Food Chem. | pmid:28562041 |
| Wang G et al. | Development of Multifunctional Avermectin Poly(succinimide) Nanoparticles to Improve Bioactivity and Transportation in Rice. | 2018 | J. Agric. Food Chem. | pmid:30299946 |
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| Türkan F et al. | The toxicological impact of some avermectins on human erythrocytes glutathione S-transferase enzyme. | 2018 | J. Biochem. Mol. Toxicol. | pmid:30091233 |
| Conforti S et al. | Comparative effects of the parasiticide ivermectin on survival and reproduction of adult sepsid flies. | 2018 | Ecotoxicol. Environ. Saf. | pmid:30055386 |
| Guan W et al. | Fabrication of an Effective Avermectin Nanoemulsion Using a Cleavable Succinic Ester Emulsifier. | 2018 | J. Agric. Food Chem. | pmid:29976065 |
| Dos Santos Moreira AM et al. | Hydrophobic Nanoprecipitates of β-Cyclodextrin/Avermectins Inclusion Compounds Reveal Insecticide Activity against Aedes aegypti Larvae and Low Toxicity against Fibroblasts. | 2018 | J. Agric. Food Chem. | pmid:29925239 |
| Florez DHÂ et al. | Pipette-tip solid-phase extraction using polypyrrole as efficient adsorbent for extraction of avermectins and milbemycins in milk. | 2018 | Anal Bioanal Chem | pmid:29607449 |
| Liang W et al. | Chitosan-based nanoparticles of avermectin to control pine wood nematodes. | 2018 | Int. J. Biol. Macromol. | pmid:29382581 |
| Liang J et al. | Bioinspired Development of P(St-MAA)-Avermectin Nanoparticles with High Affinity for Foliage To Enhance Folia Retention. | 2018 | J. Agric. Food Chem. | pmid:28727420 |
| Guan W et al. | Fabrication of Novel Avermectin Nanoemulsion Using a Polyurethane Emulsifier with Cleavable Disulfide Bonds. | 2018 | J. Agric. Food Chem. | pmid:28700229 |
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| Brownjohn PW et al. | Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease. | 2017 | Stem Cell Reports | pmid:28285880 |
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| Zhang W et al. | Determination of avermectins by the internal standard recovery correction - high performance liquid chromatography - quantitative Nuclear Magnetic Resonance method. | 2017 | Talanta | pmid:28602306 |
| Silva GRD et al. | Multiresidue method for identification and quantification of avermectins, benzimidazoles and nitroimidazoles residues in bovine muscle tissue by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) using a QuEChERS approach. | 2017 | Talanta | pmid:28551144 |
| Liu X et al. | Redox-sensing regulator Rex regulates aerobic metabolism, morphological differentiation, and avermectin production in Streptomyces avermitilis. | 2017 | Sci Rep | pmid:28303934 |
| Zhao X et al. | Pesticide-mediated interspecific competition between local and invasive thrips pests. | 2017 | Sci Rep | pmid:28084404 |
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| Mermans C et al. | A G326E substitution in the glutamate-gated chloride channel 3 (GluCl3) of the two-spotted spider mite Tetranychus urticae abolishes the agonistic activity of macrocyclic lactones. | 2017 | Pest Manag. Sci. | pmid:28736919 |
| Suroto DA et al. | Activation of cryptic phthoxazolin A production in Streptomyces avermitilis by the disruption of autoregulator-receptor homologue AvaR3. | 2017 | J. Biosci. Bioeng. | pmid:28728974 |
| Falkenberg LJ et al. | Low sensitivity of reproductive life-stages in the Pacific oyster (Crassostrea gigas) to abamectin. | 2017 | Chemosphere | pmid:28528312 |
| Zhang Y et al. | New Avermectin Analogues from a Mutant Streptomyces avermectinius Strain. | 2017 | Chem. Biodivers. | pmid:28387012 |
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| Liu C et al. | Avermectin induced global DNA hypomethylation and over-expression of heat shock proteins in cardiac tissues of pigeon. | 2017 | Pestic Biochem Physiol | pmid:28043331 |
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| You X et al. | Preparation of magnetic molecularly imprinted polymers by atom transfer radical polymerization for the rapid extraction of avermectin from fish samples. | 2017 | J Sep Sci | pmid:27860252 |
| Zhang Y et al. | Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays. | 2017 | Environ. Pollut. | pmid:27852506 |
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| Qin Y et al. | Analysis of sulfonamides, tilmicosin and avermectins residues in typical animal matrices with multi-plug filtration cleanup by liquid chromatography-tandem mass spectrometry detection. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28410479 |
| Zhu J et al. | AvaR2, a pseudo γ-butyrolactone receptor homologue from Streptomyces avermitilis, is a pleiotropic repressor of avermectin and avenolide biosynthesis and cell growth. | 2016 | Mol. Microbiol. | pmid:27502190 |
| Guo J et al. | Raising the avermectins production in Streptomyces avermitilis by utilizing nanosecond pulsed electric fields (nsPEFs). | 2016 | Sci Rep | pmid:27181521 |
| Sun D et al. | SAV742, a Novel AraC-Family Regulator from Streptomyces avermitilis, Controls Avermectin Biosynthesis, Cell Growth and Development. | 2016 | Sci Rep | pmid:27841302 |
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| Zhang J et al. | Synthesis, biological activities and structure-activity relationships for new avermectin analogues. | 2016 | Eur J Med Chem | pmid:27318119 |
| Dos Anjos MR et al. | Multiresidue method for simultaneous analysis of aflatoxin M1, avermectins, organophosphate pesticides and milbemycin in milk by ultra-performance liquid chromatography coupled to tandem mass spectrometry. | 2016 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:27144891 |
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