Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Dog Diseases D004283 5 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Fish Diseases D005393 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Ostertagiasis D010029 2 associated lipids
Strongylida Infections D017206 5 associated lipids
Trichostrongylosis D014253 5 associated lipids
Lice Infestations D010373 9 associated lipids
Ectoparasitic Infestations D004478 2 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Parasitic Diseases, Animal D010273 1 associated lipids
Scabies D012532 2 associated lipids
Larva Migrans D007815 1 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Brownjohn PW et al. Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease. 2017 Stem Cell Reports pmid:28285880
Cui Q et al. Avermectin biosynthesis: stable functional expression of branched chain α-keto acid dehydrogenase complex from Streptomyces avermitilis in Escherichia coli by selectively regulating individual subunit gene expression. 2017 Biotechnol. Lett. pmid:28664314
Falkenberg LJ et al. Low sensitivity of reproductive life-stages in the Pacific oyster (Crassostrea gigas) to abamectin. 2017 Chemosphere pmid:28528312
Zhang Y et al. New Avermectin Analogues from a Mutant Streptomyces avermectinius Strain. 2017 Chem. Biodivers. pmid:28387012
Wang YS et al. A spectrophotometric screening method for avermectin oxidizing microorganisms. 2017 J. Microbiol. Methods pmid:28215961
Liu C et al. Avermectin induced global DNA hypomethylation and over-expression of heat shock proteins in cardiac tissues of pigeon. 2017 Pestic Biochem Physiol pmid:28043331
Tian P et al. Comparative metabolomics reveals the mechanism of avermectin production enhancement by S-adenosylmethionine. 2017 J. Ind. Microbiol. Biotechnol. pmid:27988821
Iwai Y Anecdote of the ÅŒmura laboratory and the discovery of avermectin. 2017 Biosci. Biotechnol. Biochem. pmid:27885935
Takahashi Y Continuing fascination of exploration in natural substances from microorganisms. 2017 Biosci. Biotechnol. Biochem. pmid:27885930
Qin Y et al. Analysis of sulfonamides, tilmicosin and avermectins residues in typical animal matrices with multi-plug filtration cleanup by liquid chromatography-tandem mass spectrometry detection. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28410479