| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dog Diseases | D004283 | 5 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Poisoning | D011041 | 9 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
| Fish Diseases | D005393 | 5 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Ostertagiasis | D010029 | 2 associated lipids |
| Strongylida Infections | D017206 | 5 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Lice Infestations | D010373 | 9 associated lipids |
| Ectoparasitic Infestations | D004478 | 2 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Parasitic Diseases, Animal | D010273 | 1 associated lipids |
| Scabies | D012532 | 2 associated lipids |
| Larva Migrans | D007815 | 1 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Campbell WC | History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents. | 2012 | Curr Pharm Biotechnol | pmid:22039784 |
| Danaher M et al. | Recent developments in the analysis of avermectin and milbemycin residues in food safety and the environment. | 2012 | Curr Pharm Biotechnol | pmid:22039790 |
| Horsberg TE | Avermectin use in aquaculture. | 2012 | Curr Pharm Biotechnol | pmid:22039799 |
| Jiang X et al. | Expression of CYP107Z13 in Streptomyces lividans TK54 catalyzes the oxidation of avermectin to 4″-oxo-avermectin. | 2012 | Appl. Microbiol. Biotechnol. | pmid:21842154 |
| Tao Y et al. | Determination of 17 macrolide antibiotics and avermectins residues in meat with accelerated solvent extraction by liquid chromatography-tandem mass spectrometry. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:22542398 |
| Lin YY et al. | Differential susceptibilities of Brontispa longissima (Coleoptera: Hispidae) to insecticides in Southeast Asia. | 2012 | J. Econ. Entomol. | pmid:22812140 |
| Liu GD et al. | [Hemoperfusion in the treatment of an acute avermectin poisoning patient with liver cirrhosis]. | 2012 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:22730696 |
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| Alves SN et al. | [Susceptibility of Culex quinquefasciatus larvae to different insecticides]. | 2011 Jul-Aug | Rev. Soc. Bras. Med. Trop. | pmid:21860896 |
| Rezanka T et al. | Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces. | 2011 | Environ. Microbiol. | pmid:21450004 |
| Sargison ND et al. | Effects of age and immune suppression of sheep on fecundity, hatching and larval feeding of different strains of Haemonchus contortus. | 2011 | Vet. J. | pmid:20822936 |
| Guan HN et al. | Novel photodegradable insecticide W/TiO(2)/Avermectin nanocomposites obtained by polyelectrolytes assembly. | 2011 | Colloids Surf B Biointerfaces | pmid:21131183 |
| Sherman JG | Understanding the impact of P-glycoprotein mutation on canine health. | 2011 | Vet. J. | pmid:21106417 |
| Miyamoto KT et al. | The autoregulator receptor homologue AvaR3 plays a regulatory role in antibiotic production, mycelial aggregation and colony development of Streptomyces avermitilis. | 2011 | Microbiology (Reading, Engl.) | pmid:21622528 |
| Qiu J et al. | Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21713508 |
| Jiang L et al. | Inactivation of the extracytoplasmic function sigma factor Sig6 stimulates avermectin production in Streptomyces avermitilis. | 2011 | Biotechnol. Lett. | pmid:21691838 |
| Wang XX et al. | Yeast screening from avermectins wastewater and investigation on the ability of its fermentation. | 2011 | Bioprocess Biosyst Eng | pmid:21698347 |
| Gong X et al. | [Determination of avermectin, diclazuril, toltrazuril and metabolite residues in pork by high performance liquid chromatography-tandem mass spectrometry]. | 2011 | Se Pu | pmid:21657050 |
| Wang JB et al. | Production of doramectin by rational engineering of the avermectin biosynthetic pathway. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21514826 |
| Wang F et al. | Multi-residue method for the confirmation of four avermectin residues in food products of animal origin by ultra-performance liquid chromatography-tandem mass spectrometry. | 2011 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21598143 |
| Jin T et al. | Insecticide resistance of the oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae), in mainland China. | 2011 | Pest Manag. Sci. | pmid:21308963 |
| He HG et al. | [Resistance realized heritability and risk assessment of Panonychus citri to avermectin and fenpropathrin]. | 2011 | Ying Yong Sheng Tai Xue Bao | pmid:22097380 |
| Liu M et al. | Magnetic field is the dominant factor to induce the response of Streptomyces avermitilis in altered gravity simulated by diamagnetic levitation. | 2011 | PLoS ONE | pmid:22039402 |
| Kitani S et al. | Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21930904 |
| Liu C et al. | [Analysis of methanogenic community of anaerobic granular sludge based on mcrA gene]. | 2011 | Huan Jing Ke Xue | pmid:21717756 |
| Gao Y et al. | Species displacements are common to two invasive species of leafminer fly in China, Japan, and the United States. | 2011 | J. Econ. Entomol. | pmid:22299335 |
| Huang J et al. | Molecular characterization of the sigma class gutathione S-transferase from Chilo suppressalis and expression analysis upon bacterial and insecticidal challenge. | 2011 | J. Econ. Entomol. | pmid:22299369 |
| Jiao YL et al. | Function analysis of a new type I PKS-SAT domain by SAT-EAT domain replacement. | 2010 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:20391758 |
| Tom LA and Foster N | Development of a molecularly imprinted polymer for the analysis of avermectin. | 2010 | Anal. Chim. Acta | pmid:20969995 |
| Wolstenholme AJ | Recent progress in understanding the interaction between avermectins and ligand-gated ion channels: putting the pests to sleep. | 2010 | Invert. Neurosci. | pmid:20953673 |
| Webb L et al. | Field-scale dispersal of Aphodius dung beetles (Coleoptera: Scarabaeidae) in response to avermectin treatments on pastured cattle. | 2010 | Bull. Entomol. Res. | pmid:19586576 |
| Li L et al. | Overexpression of ribosome recycling factor causes increased production of avermectin in Streptomyces avermitilis strains. | 2010 | J. Ind. Microbiol. Biotechnol. | pmid:20352288 |
| Molinari G et al. | New ventures in the genotoxic and cytotoxic effects of macrocyclic lactones, abamectin and ivermectin. | 2010 | Cytogenet. Genome Res. | pmid:20389039 |
| Liu C et al. | [Analysis of methanogenic community of anaerobic granular sludge in a full-scale UASB treating avermectin wastewater]. | 2010 | Huan Jing Ke Xue | pmid:20358834 |
| Guo J et al. | The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis. | 2010 | Mol. Genet. Genomics | pmid:20012992 |
| Sperry J et al. | Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction. | 2010 | Org. Biomol. Chem. | pmid:20024126 |
| Gao H et al. | Identification of avermectin-high-producing strains by high-throughput screening methods. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19957083 |
| Alves SN et al. | Alterations in the fat body and midgut of Culex quinquefasciatus larvae following exposure to different insecticides. | 2010 | Micron | pmid:20452779 |
| Gao H et al. | Assessing the potential of an induced-mutation strategy for avermectin overproducers. | 2010 | Appl. Environ. Microbiol. | pmid:20453119 |
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| Hassan MU et al. | Bovine hypodermosis--a global aspect. | 2010 | Trop Anim Health Prod | pmid:20607401 |
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| Li M et al. | Enhancement of avermectin and ivermectin production by overexpression of the maltose ATP-binding cassette transporter in Streptomyces avermitilis. | 2010 | Bioresour. Technol. | pmid:20655739 |
| Whelan M et al. | Determination of anthelmintic drug residues in milk using ultra high performance liquid chromatography-tandem mass spectrometry with rapid polarity switching. | 2010 | J Chromatogr A | pmid:20564781 |
| Sargison ND et al. | Characterisation of milbemycin-, avermectin-, imidazothiazole- and benzimidazole-resistant Teladorsagia circumcincta from a sheep flock. | 2010 | Vet. Rec. | pmid:20511651 |
| Zhuo Y et al. | Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20534557 |
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| Pitterna T et al. | New ventures in the chemistry of avermectins. | 2009 | Bioorg. Med. Chem. | pmid:19168364 |
| Inoue K et al. | Simultaneous determination of avermectins in bovine tissues by LC-MS/MS. | 2009 | J Sep Sci | pmid:19877150 |