Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Trichostrongyloidiasis D014252 7 associated lipids
Lice Infestations D010373 9 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

Related references are published most in these journals:

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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Shoop WL et al. Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. 1996 Int. J. Parasitol. pmid:9024867
Shoop WL et al. Efficacy in sheep and pharmacokinetics in cattle that led to the selection of eprinomectin as a topical endectocide for cattle. 1996 Int. J. Parasitol. pmid:9024866
McKellar QA and Benchaoui HA Avermectins and milbemycins. 1996 J. Vet. Pharmacol. Ther. pmid:8905567
Titchener RN and Purnell RE Duration of persistence of injectable avermectins against sucking lice of cattle. 1996 Vet. Rec. pmid:8903014
Venkatachalam MA et al. Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels. 1996 Kidney Int. pmid:8821829
Herd R Ecotoxicity of the avermectins: a reply to Forbes. 1996 Int. J. Parasitol. pmid:8818740
Gill JH and Redwin JM Cryopreservation of the first-stage larvae of trichostrongylid nematode parasites. 1995 Int. J. Parasitol. pmid:8719953
Mironov VA et al. [Activity of threonine deaminase and biosynthesis of avermectins in the culture of Streptomyces avermitilis]. 1995 Antibiot. Khimioter. pmid:8713429
Cully DF et al. Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectin. 1996 J. Biol. Chem. pmid:8702744
Vercruysse J and Claerebout E Effect of chemoprophylaxis on immunity to gastrointestinal nematodes in cattle. 1996 Verh. K. Acad. Geneeskd. Belg. pmid:8701602
Löwenstein M et al. Histology of the skin and determination of blood and serum parameters during the recovery phase of sarcoptic manage in cattle after avermectin (Ivomec) treatment. 1996 Appl. Parasitol. pmid:8688864
MacNeil DJ Avermectins. 1995 Biotechnology pmid:8688633
Nari A et al. The prevalence of anthelmintic resistance in nematode parasites of sheep in southern Latin America: Uruguay. 1996 Vet. Parasitol. pmid:8686167
Sergeev AV et al. [Effect of nitrogen-containing compounds on the biosynthesis of avermectins]. 1995 Antibiot. Khimioter. pmid:8645056
MacNeil T et al. Deletion analysis of the avermectin biosynthetic genes of Streptomyces avermitilis by gene cluster displacement. 1993 J. Bacteriol. pmid:8478321
Novák J et al. Instability of the production of avermectins, sporulation, and pigmentation in Streptomyces avermitilis. 1993 Can. J. Microbiol. pmid:8467423
Ikeda H et al. Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis. 1993 J. Bacteriol. pmid:8384619
Sams R Chemical assay of avermectins by high performance liquid chromatography with fluorescence detection. 1993 Vet. Parasitol. pmid:8346649
Herd R et al. Research recommendations. 1993 Vet. Parasitol. pmid:8346647
Strong L Overview: the impact of avermectins on pastureland ecology. 1993 Vet. Parasitol. pmid:8346644