| MeSH term | MeSH ID | Detail |
|---|---|---|
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Lice Infestations | D010373 | 9 associated lipids |
| Poisoning | D011041 | 9 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Driniaev VA et al. | [Selective cytostatic and cytotoxic effects of avermectins]. | 2001 | Antibiot. Khimioter. | pmid:11558448 |
| Driniaev VA et al. | [Effect of avermectns on Ca(2+)-dependent chloride currents in plasmalemma of Chara corallina cells]. | 2001 | Antibiot. Khimioter. | pmid:11558454 |
| Danaher M et al. | Extraction and isolation of avermectins and milbemycins from liver samples using unmodified supercritical CO2 with in-line trapping on basic alumina. | 2001 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:11585125 |
| Ikeda H et al. | Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis: analysis of enzymatic domains in four polyketide synthases. | 2001 | J. Ind. Microbiol. Biotechnol. | pmid:11780788 |
| Sha CK et al. | Anionic cyclization approach toward perhydrobenzofuranone: stereocontrolled synthesis of the hexahydrobenzofuran subunit of avermectin. | 2002 | J. Org. Chem. | pmid:11856026 |
| Miakisheva SN et al. | [Proliferation and morphological differentiation of neurblastoma cells in cultured under the effect of avermectins]. | 2001 | Morfologiia | pmid:12016760 |
| Veale PI | Resistance to macrocyclic lactones in nematodes of goats. | 2002 | Aust. Vet. J. | pmid:12074315 |
| Deger Y et al. | Short communication serum copper, zinc, and calcium concentrations in lice-infested sheep. | 2002 | Biol Trace Elem Res | pmid:12117268 |
| Rehbein S et al. | Efficacy of a new long-acting formulation of ivermectin and other injectable avermectins against induced Psoroptes ovis infestations in cattle. | 2002 | Parasitol. Res. | pmid:12444456 |
| Kim SB and Goodfellow M | Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. | 2002 | Int. J. Syst. Evol. Microbiol. | pmid:12508861 |
| Takahashi Y et al. | Streptomyces avermectinius sp. nov., an avermectin-producing strain. | 2002 | Int. J. Syst. Evol. Microbiol. | pmid:12508884 |
| Argentine JA et al. | Toxicities of emamectin benzoate homologues and photodegradates to Lepidoptera. | 2002 | J. Econ. Entomol. | pmid:12539830 |
| Chen Z et al. | [Effect of gene disruption of aveD on avermectins production in Streptomyces avermitilis]. | 2001 | Wei Sheng Wu Xue Bao | pmid:12552909 |
| Hwang YS et al. | Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains. | 2003 | Appl. Environ. Microbiol. | pmid:12571055 |
| Martins JR et al. | Partial strategic tick control within a herd of European breed cattle in the state of Rio Grande do Sul, southern Brazil. | 2002 | Exp. Appl. Acarol. | pmid:12593589 |
| Stutzman-Engwall K et al. | Engineering the aveC gene to enhance the ratio of doramectin to its CHC-B2 analogue produced in Streptomyces avermitilis. | 2003 | Biotechnol. Bioeng. | pmid:12599263 |
| Mironov VA et al. | [Dependence of the composition of the avermectin complex of Streptomyces avermitilis on glucose content of the growth medium]. | 2003 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:12722656 |
| Viktorov AV et al. | [Comparative analysis of degradation of native avermectins and spinosyns by UV-HPLC]. | 2002 | Antibiot. Khimioter. | pmid:12728628 |
| Iovchev M et al. | Altered drug resistance and recovery from paralysis in Drosophila melanogaster with a deficient histamine-gated chloride channel. | 2002 Oct-Dec | J. Neurogenet. | pmid:12745634 |
| Arena JP et al. | Expression of a glutamate-activated chloride current in Xenopus oocytes injected with Caenorhabditis elegans RNA: evidence for modulation by avermectin. | 1992 | Brain Res. Mol. Brain Res. | pmid:1279355 |