Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Trichostrongyloidiasis D014252 7 associated lipids
Lice Infestations D010373 9 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

Related references are published most in these journals:

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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Takahashi Y et al. Streptomyces avermectinius sp. nov., an avermectin-producing strain. 2002 Int. J. Syst. Evol. Microbiol. pmid:12508884
Argentine JA et al. Toxicities of emamectin benzoate homologues and photodegradates to Lepidoptera. 2002 J. Econ. Entomol. pmid:12539830
Chen Z et al. [Effect of gene disruption of aveD on avermectins production in Streptomyces avermitilis]. 2001 Wei Sheng Wu Xue Bao pmid:12552909
Hwang YS et al. Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains. 2003 Appl. Environ. Microbiol. pmid:12571055
Martins JR et al. Partial strategic tick control within a herd of European breed cattle in the state of Rio Grande do Sul, southern Brazil. 2002 Exp. Appl. Acarol. pmid:12593589
Stutzman-Engwall K et al. Engineering the aveC gene to enhance the ratio of doramectin to its CHC-B2 analogue produced in Streptomyces avermitilis. 2003 Biotechnol. Bioeng. pmid:12599263
Mironov VA et al. [Dependence of the composition of the avermectin complex of Streptomyces avermitilis on glucose content of the growth medium]. 2003 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:12722656
Viktorov AV et al. [Comparative analysis of degradation of native avermectins and spinosyns by UV-HPLC]. 2002 Antibiot. Khimioter. pmid:12728628
Iovchev M et al. Altered drug resistance and recovery from paralysis in Drosophila melanogaster with a deficient histamine-gated chloride channel. 2002 Oct-Dec J. Neurogenet. pmid:12745634
Arena JP et al. Expression of a glutamate-activated chloride current in Xenopus oocytes injected with Caenorhabditis elegans RNA: evidence for modulation by avermectin. 1992 Brain Res. Mol. Brain Res. pmid:1279355