Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Parasitic Diseases, Animal D010273 1 associated lipids
Lice Infestations D010373 9 associated lipids
Poisoning D011041 9 associated lipids
Scabies D012532 2 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Trichostrongylosis D014253 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Alves SN et al. [Susceptibility of Culex quinquefasciatus larvae to different insecticides]. 2011 Jul-Aug Rev. Soc. Bras. Med. Trop. pmid:21860896
de Macedo DM et al. [Post-embrionic development of Stomoxys calcitrans (Linnaeus,1758) (Diptera: Muscidae)feed in feces of treated bovines with different avermectins]. 2005 Apr-Jun Rev Bras Parasitol Vet pmid:16153344
Ostlind DA and Cifelli S Efficacy of thiabendazole, levamisole hydrochloride and the major natural avermectins against Trichostrongylus colubriformis in the gerbil (Meriones unguiculatus). 1981 Res. Vet. Sci. pmid:7323472
Lonneux JF et al. Antibody response after treatment in cattle infected with Psoroptes ovis. 1997 Jul-Aug Res. Vet. Sci. pmid:9368957
Lankas GR et al. Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice. 1998 Jul-Aug Reprod. Toxicol. pmid:9717696
Gianelli L et al. Mass spectrometry of avermectins: structural determination of two new derivatives of Ivermectin B(1a). 2000 Rapid Commun. Mass Spectrom. pmid:10918377
Turnipseed SB et al. No-discharge atmospheric pressure chemical ionization: evaluation and application to the analysis of animal drug residues in complex matrices. 2006 Rapid Commun. Mass Spectrom. pmid:16541409
Turnipseed SB et al. Confirmation of avermectin residues in food matrices with negative-ion atmospheric pressure chemical ionization liquid chromatography/mass spectrometry. 1999 Rapid Commun. Mass Spectrom. pmid:10204245
Ikeda H et al. Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10449723
Rohrer SP et al. Photoaffinity labeling of avermectin binding sites from Caenorhabditis elegans and Drosophila melanogaster. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1315055