Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Parasitic Diseases, Animal D010273 1 associated lipids
Larva Migrans D007815 1 associated lipids
Ectoparasitic Infestations D004478 2 associated lipids
Scabies D012532 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Fish Diseases D005393 5 associated lipids
Dog Diseases D004283 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Trichostrongylosis D014253 5 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Authors Title Published Journal PubMed Link
Pivnichny JV et al. Direct determination of avermectins in plasma at nanogram levels by high-performance liquid chromatography. 1983 J Pharm Sci pmid:6663483
Drexler G and Sieghart W Evidence for association of a high affinity avermectin binding site with the benzodiazepine receptor. 1984 Eur. J. Pharmacol. pmid:6088254
Kass IS et al. The effects of avermectin and drugs related to acetylcholine and 4-aminobutyric acid on neurotransmission in Ascaris suum. 1984 Mol. Biochem. Parasitol. pmid:6096713
Drexler G and Sieghart W [35S]tert.-butylbicyclophosphorothionate and avermectin bind to different sites associated with the gamma- aminobutyric acid-benzodiazepine receptor complex. 1984 Neurosci. Lett. pmid:6093013
Calcott PH and Fatig RO Inhibition of chitin metabolism by avermectin in susceptible organisms. 1984 J. Antibiot. pmid:6725140
Goodwin LG Recent advances in research on filariasis. Chemotherapy. 1984 Trans. R. Soc. Trop. Med. Hyg. pmid:6382706
Parrish MD and Roberts RB Toxicity of avermectin B1 to larval yellowjackets, Vespula maculifrons (Hymenoptera: Vespidae). 1984 J. Econ. Entomol. pmid:6480980
Calcott PH and Fatig RO Avermectin modulation of GABA binding to membranes of rat brain, brine shrimp and a fungus, Mucor miehei. 1984 J. Antibiot. pmid:6088460
BronshteÄ­n AM [Praziquantel and other current preparations and chemotherapy methods in human trematodiases of the liver (opisthorchiasis and clonorchiasis) (a review of the literature)]. 1984 Nov-Dec Med Parazitol (Mosk) pmid:6397686
Schulman MD et al. Demethylavermectins. Biosynthesis, isolation and characterization. 1985 J. Antibiot. pmid:4077729