Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Parasitic Diseases, Animal D010273 1 associated lipids
Larva Migrans D007815 1 associated lipids
Ectoparasitic Infestations D004478 2 associated lipids
Scabies D012532 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Fish Diseases D005393 5 associated lipids
Dog Diseases D004283 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Trichostrongylosis D014253 5 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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What lipids are associated with Avermectin A1a?

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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Authors Title Published Journal PubMed Link
Seaman JT et al. Avermectin B1 toxicity in a herd of Murray Grey cattle. 1987 Aust. Vet. J. pmid:3426470
Wright DJ Avermectins: action on target pest species. 1987 Biochem. Soc. Trans. pmid:2435585
Gordnier PM et al. Chitin metabolism: not a target of avermectin/milbemycin activity in insects. 1987 J. Antibiot. pmid:2951358
Matsumoto K et al. Actions of avermectins on cultured neurons. 1988 Gen. Pharmacol. pmid:3044917
Ikeda H et al. Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis. 1988 Antimicrob. Agents Chemother. pmid:3364948
De Chaneet GC et al. Effect of avermectin B1 and benzimidazole anthelmintics on worm egg output of treated cattle. 1988 Aust. Vet. J. pmid:3401149
Button C et al. Avermectin toxicity in calves and an evaluation of picrotoxin as an antidote. 1988 Aust. Vet. J. pmid:3401165
Chang V Toxic baiting of the Western yellowjacket (Hymenoptera: Vespidae) in Hawaii. 1988 J. Econ. Entomol. pmid:3351079
Ammendola D et al. Anticonvulsant effects of avermectin in DBA/2 mice and rat. 1988 Exp Biol pmid:3268424
Chen TS et al. Directed biosynthesis of avermectins. 1989 Arch. Biochem. Biophys. pmid:2919882