| MeSH term | MeSH ID | Detail |
|---|---|---|
| Larva Migrans | D007815 | 1 associated lipids |
| Parasitic Diseases, Animal | D010273 | 1 associated lipids |
| Scabies | D012532 | 2 associated lipids |
| Ostertagiasis | D010029 | 2 associated lipids |
| Ectoparasitic Infestations | D004478 | 2 associated lipids |
| Dog Diseases | D004283 | 5 associated lipids |
| Strongylida Infections | D017206 | 5 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Fish Diseases | D005393 | 5 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sheehan LS et al. | Engineering of the spinosyn PKS: directing starter unit incorporation. | 2006 | J. Nat. Prod. | pmid:17190446 |
| Li ZZ et al. | Controlled release of avermectin from porous hollow silica nanoparticles: influence of shell thickness on loading efficiency, UV-shielding property and release. | 2006 | J Control Release | pmid:16388871 |
| He J et al. | Multiresidue analysis of avermectins in bovine liver by immunoaffinity column cleanup procedure and liquid chromatography with fluorescence detector. | 2005 Jul-Aug | J AOAC Int | pmid:16152926 |
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| Walsh CT | Natural insights for chemical biologists. | 2005 | Nat. Chem. Biol. | pmid:16408011 |
| Jungmann V et al. | Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes. | 2005 | Appl. Environ. Microbiol. | pmid:16269732 |
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| Erzen NK et al. | Degradation of abamectin and doramectin on sheep grazed pasture. | 2005 | Ecotoxicology | pmid:16215697 |
| Bowen JM and Vitayavirasak B | Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds. | 2005 | Vet. Parasitol. | pmid:16076531 |
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| Yong JH and Byeon WH | Alternative production of avermectin components in Streptomyces avermitilis by gene replacement. | 2005 | J. Microbiol. | pmid:15995647 |
| Kuzmina TA et al. | Analysis of the strongylid nematodes (Nematoda: Strongylidae) community after deworming of brood horses in Ukraine. | 2005 | Vet. Parasitol. | pmid:15979240 |
| Wolstenholme AJ and Rogers AT | Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics. | 2005 | Parasitology | pmid:16569295 |
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| Shi ZH et al. | Evaluation of selective toxicity of five pesticides against Plutella xylostella (Lep: Plutellidae) and their side-effects against Cotesia plutellae (Hym: Braconidae) and Oomyzus sokolowskii (Hym: Eulophidae). | 2004 | Pest Manag. Sci. | pmid:15578602 |
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| Gong W et al. | Improvement of transformation and electroduction in avermectin high-producer, Streptomyces avermitilis. | 2004 | Folia Microbiol. (Praha) | pmid:15530004 |
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| Hwang YS et al. | Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains. | 2003 | Appl. Environ. Microbiol. | pmid:12571055 |
| Blackhall WJ et al. | Selection at a gamma-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins. | 2003 | Mol. Biochem. Parasitol. | pmid:14511812 |
| Nagai K et al. | Synthesis and biological activities of novel 4"-alkylidene avermectin derivatives. | 2003 | Bioorg. Med. Chem. Lett. | pmid:14592480 |
| Strabel D et al. | [The use of avermectins in two goats with demodicosis]. | 2003 | Schweiz. Arch. Tierheilkd. | pmid:14725185 |
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