| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
| Dog Diseases | D004283 | 5 associated lipids |
| Ectoparasitic Infestations | D004478 | 2 associated lipids |
| Fish Diseases | D005393 | 5 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Larva Migrans | D007815 | 1 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Ostertagiasis | D010029 | 2 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gill JH and Redwin JM | Cryopreservation of the first-stage larvae of trichostrongylid nematode parasites. | 1995 | Int. J. Parasitol. | pmid:8719953 |
| Herd R | Ecotoxicity of the avermectins: a reply to Forbes. | 1996 | Int. J. Parasitol. | pmid:8818740 |
| Venkatachalam MA et al. | Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels. | 1996 | Kidney Int. | pmid:8821829 |
| Titchener RN and Purnell RE | Duration of persistence of injectable avermectins against sucking lice of cattle. | 1996 | Vet. Rec. | pmid:8903014 |
| McKellar QA and Benchaoui HA | Avermectins and milbemycins. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8905567 |
| Shoop WL et al. | Efficacy in sheep and pharmacokinetics in cattle that led to the selection of eprinomectin as a topical endectocide for cattle. | 1996 | Int. J. Parasitol. | pmid:9024866 |
| Shoop WL et al. | Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. | 1996 | Int. J. Parasitol. | pmid:9024867 |
| Krieger RI et al. | Adult and infant abamectin exposures following Avert 310 and pressurized gel crack and crevice treatment. | 1997 | Bull Environ Contam Toxicol | pmid:9115128 |
| Vassilatis DK et al. | Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels. | 1997 | J. Mol. Evol. | pmid:9115174 |
| Gray AK | Avermectin toxicity in the dog. | 1997 | Vet. Rec. | pmid:9185316 |
| Scarff DH | Avermectin toxicity in the dog. | 1997 | Vet. Rec. | pmid:9185317 |
| Pomes A et al. | Target size analysis of an avermectin binding site from Drosophila melanogaster. | 1997 | Biochim. Biophys. Acta | pmid:9187243 |
| Laughton DL et al. | Reporter gene constructs suggest that the Caenorhabditis elegans avermectin receptor beta-subunit is expressed solely in the pharynx. | 1997 | J. Exp. Biol. | pmid:9192499 |
| Doody GM | Avermectin toxicity in the dog. | 1997 | Vet. Rec. | pmid:9203324 |
| Mironov VA et al. | [Biosynthesis of avermectins: physiological and technological aspects]. | 1997 | Antibiot. Khimioter. | pmid:9265465 |
| Lonneux JF et al. | Antibody response after treatment in cattle infected with Psoroptes ovis. | 1997 Jul-Aug | Res. Vet. Sci. | pmid:9368957 |
| Barnes TM and Hekimi S | The Caenorhabditis elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells. | 1997 | J. Neurochem. | pmid:9375655 |
| Vassilatis DK et al. | Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization. | 1997 | J. Biol. Chem. | pmid:9407104 |
| Marsden AF et al. | Engineering broader specificity into an antibiotic-producing polyketide synthase. | 1998 | Science | pmid:9422686 |
| Ikeda H et al. | Cloning of the gene encoding avermectin B 5-O-methyltransferase in avermectin-producing Streptomyces avermitilis. | 1998 | Gene | pmid:9469930 |
| Gill JH et al. | Evidence of multiple mechanisms of avermectin resistance in haemonchus contortus--comparison of selection protocols. | 1998 | Int. J. Parasitol. | pmid:9650059 |
| Lonneux JF et al. | The relationship between parasite counts, lesions, antibody titres and daily weight gains in Psoroptes ovis infested cattle. | 1998 | Vet. Parasitol. | pmid:9653998 |
| Gill JH and Lacey E | Avermectin/milbemycin resistance in trichostrongyloid nematodes. | 1998 | Int. J. Parasitol. | pmid:9673866 |
| Lankas GR et al. | Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice. | 1998 Jul-Aug | Reprod. Toxicol. | pmid:9717696 |
| Delany NS et al. | Cloning and localisation of an avermectin receptor-related subunit from Haemonchus contortus. | 1998 | Mol. Biochem. Parasitol. | pmid:9879896 |
| Windelspecht M et al. | Survey of malathion resistance and avermectin susceptibility in field populations of Drosophila melanogaster (Diptera: Drosophilidae) and D. simulans. | 1998 | J. Econ. Entomol. | pmid:9887681 |
| Meinke PT et al. | Synthesis of gem-difluoro-avermectin derivatives: potent anthelmintic and anticonvulsant agents. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9934486 |