| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
| Dog Diseases | D004283 | 5 associated lipids |
| Ectoparasitic Infestations | D004478 | 2 associated lipids |
| Fish Diseases | D005393 | 5 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Larva Migrans | D007815 | 1 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Ostertagiasis | D010029 | 2 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Korystov YN et al. | Avermectins inhibit multidrug resistance of tumor cells. | 2004 | Eur. J. Pharmacol. | pmid:15189764 |
| Ammendola D et al. | Anticonvulsant effects of avermectin in DBA/2 mice and rat. | 1988 | Exp Biol | pmid:3268424 |
| Martins JR et al. | Partial strategic tick control within a herd of European breed cattle in the state of Rio Grande do Sul, southern Brazil. | 2002 | Exp. Appl. Acarol. | pmid:12593589 |
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| Rezanka T et al. | Influence of inhibitors of lipid biosynthesis on the production of avermectins in Streptomyces avermitilis. | 1992 | FEMS Microbiol. Lett. | pmid:1526463 |
| Boden R | Editorial: on artemisinin, avermectins and Nobel Prizes. | 2015 | FEMS Microbiol. Lett. | pmid:26486159 |
| Novák J et al. | Nitrogen regulation of fatty acids and avermectins biosynthesis in Streptomyces avermitilis. | 1992 | FEMS Microbiol. Lett. | pmid:1612418 |
| Zhao Y et al. | Isolation, characterization, and tissue-specific expression of GABA A receptor α1 subunit gene of Carassius auratus gibelio after avermectin treatment. | 2016 | Fish Physiol. Biochem. | pmid:26318443 |
| Rezanka T et al. | Relationship between volatile odorous substances and production of avermectins by Streptomyces avermitilis. | 2007 | Folia Microbiol. (Praha) | pmid:17571791 |
| Gong W et al. | Improvement of transformation and electroduction in avermectin high-producer, Streptomyces avermitilis. | 2004 | Folia Microbiol. (Praha) | pmid:15530004 |
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| MacNeil DJ et al. | Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector. | 1992 | Gene | pmid:1547955 |
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| Shiwen X et al. | Preparation and characterization of monoclonal antibodies against avermectin. | 2009 | Hybridoma (Larchmt) | pmid:19519244 |
| Tambo E et al. | Nobel prize for the artemisinin and ivermectin discoveries: a great boost towards elimination of the global infectious diseases of poverty. | 2015 | Infect Dis Poverty | pmid:26708575 |
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| Liang W et al. | Chitosan-based nanoparticles of avermectin to control pine wood nematodes. | 2018 | Int. J. Biol. Macromol. | pmid:29382581 |
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| Herd R | Ecotoxicity of the avermectins: a reply to Forbes. | 1996 | Int. J. Parasitol. | pmid:8818740 |
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| Shoop WL et al. | Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. | 1996 | Int. J. Parasitol. | pmid:9024867 |
| Gopal RM et al. | Resistance of field isolates of Trichostrongylus colubriformis and Ostertagia circumcincta to ivermectin. | 1999 | Int. J. Parasitol. | pmid:10404276 |
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| Gill JH et al. | Evidence of multiple mechanisms of avermectin resistance in haemonchus contortus--comparison of selection protocols. | 1998 | Int. J. Parasitol. | pmid:9650059 |
| Kim SB and Goodfellow M | Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. | 2002 | Int. J. Syst. Evol. Microbiol. | pmid:12508861 |
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| Hou X et al. | Multiresidue analysis of avermectins in cattle liver by liquid chromatography/tandem mass spectrometry. | 2006 Jul-Aug | J AOAC Int | pmid:16915852 |
| He J et al. | Multiresidue analysis of avermectins in bovine liver by immunoaffinity column cleanup procedure and liquid chromatography with fluorescence detector. | 2005 Jul-Aug | J AOAC Int | pmid:16152926 |
| Valenzuela AI et al. | Comparison of various liquid chromatographic methods for the analysis of avermectin residues in citrus fruits. | 2001 | J Chromatogr A | pmid:11403456 |
| Krogh KA et al. | Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry. | 2008 | J Chromatogr A | pmid:18929364 |
| Whelan M et al. | Determination of anthelmintic drug residues in milk using ultra high performance liquid chromatography-tandem mass spectrometry with rapid polarity switching. | 2010 | J Chromatogr A | pmid:20564781 |
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