Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Cleft Palate D002972 9 associated lipids
Dog Diseases D004283 5 associated lipids
Ectoparasitic Infestations D004478 2 associated lipids
Fish Diseases D005393 5 associated lipids
Inflammation D007249 119 associated lipids
Larva Migrans D007815 1 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Ostertagiasis D010029 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Waller PJ et al. Regional and temporal use of avermectins for ruminants in Australia. 1993 Vet. Parasitol. pmid:8346642
McCracken DI The potential for avermectins to affect wildlife. 1993 Vet. Parasitol. pmid:8346640
King KL The potential for avermectins to affect the nutrient economy of grazed pastures. 1993 Vet. Parasitol. pmid:8346639
Ridsdill-Smith TJ Effects of avermectin residues in cattle dung on dung beetle (Coleoptera: Scarabaeidae) reproduction and survival. 1993 Vet. Parasitol. pmid:8346627
Special issue: Environmental impact of avermectin usage in livestock. 1993 Vet. Parasitol. pmid:8346625
Schulman M et al. Microbial conversion of avermectins by Saccharopolyspora erythraea: glycosylation at C-4' and C-4''. 1993 Antimicrob. Agents Chemother. pmid:8239577
Schulman M et al. Microbial conversion of avermectins by Saccharopolyspora erythraea: hydroxylation at C-27. 1994 J. Antibiot. pmid:8175491
Naito S et al. Milbemycin derivatives: modification at the C-5 position. 1994 J. Antibiot. pmid:8150720
Schönrock B and Bormann J Activation of Cl- channels by avermectin in rat cultured hippocampal neurons. 1993 Naunyn Schmiedebergs Arch. Pharmacol. pmid:8133905
Rohrer SP et al. Immunoaffinity purification of avermectin-binding proteins from the free-living nematode Caenorhabditis elegans and the fruitfly Drosophila melanogaster. 1994 Biochem. J. pmid:8092985