Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Dog Diseases D004283 5 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Fish Diseases D005393 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
pmid:
Sangster NC et al. Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins. 1999 Exp. Parasitol. pmid:10072327
Turnipseed SB et al. Confirmation of avermectin residues in food matrices with negative-ion atmospheric pressure chemical ionization liquid chromatography/mass spectrometry. 1999 Rapid Commun. Mass Spectrom. pmid:10204245
Sangster NC and Gill J Pharmacology of anthelmintic resistance. 1999 Parasitol. Today (Regul. Ed.) pmid:10322335
Gopal RM et al. Resistance of field isolates of Trichostrongylus colubriformis and Ostertagia circumcincta to ivermectin. 1999 Int. J. Parasitol. pmid:10404276
Mosin VA et al. [Action of avermectins on lymphoid leukemia P-388 cells in vitro]. 1999 Antibiot. Khimioter. pmid:10422573
Roudaut B Multiresidue method for the determination of avermectin and moxidectin residues in the liver using HPLC with fluorescence detection. 1998 Analyst pmid:10435295
Ikeda H et al. Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10449723
Geary TG et al. Frontiers in anthelmintic pharmacology. 1999 Vet. Parasitol. pmid:10456419
Sangster NC Pharmacology of anthelmintic resistance in cyathostomes: will it occur with the avermectin/milbemycins? 1999 Vet. Parasitol. pmid:10485365