Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Dog Diseases D004283 5 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Fish Diseases D005393 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Krautmann MJ et al. Safety of selamectin in cats. 2000 Vet. Parasitol. pmid:10940537
Doan HT et al. The efficacy of avermectins (ivermectin, doramectin and abamectin) as treatments for infestation with the tick Haemaphysalis longicornis on rabbits in Korea. 2013 Vet. Parasitol. pmid:24140165
Sams R Chemical assay of avermectins by high performance liquid chromatography with fluorescence detection. 1993 Vet. Parasitol. pmid:8346649
Lonneux JF et al. The relationship between parasite counts, lesions, antibody titres and daily weight gains in Psoroptes ovis infested cattle. 1998 Vet. Parasitol. pmid:9653998
Anziani OS et al. Avermectin resistance in Cooperia pectinata in cattle in Argentina. 2001 Vet. Rec. pmid:11488345
Martins JR and Furlong J Avermectin resistance of the cattle tick Boophilus microplus in Brazil. 2001 Vet. Rec. pmid:11488352
Orpin P Potential avermectin resistance in a cattle herd. 2010 Vet. Rec. pmid:20622213
Sargison ND et al. Characterisation of milbemycin-, avermectin-, imidazothiazole- and benzimidazole-resistant Teladorsagia circumcincta from a sheep flock. 2010 Vet. Rec. pmid:20511651
Marriner S Anthelmintic drugs. 1986 Vet. Rec. pmid:3962132
Shoop WL Resistance to avermectins and milbemycins. 1992 Vet. Rec. pmid:1496763
James PS et al. Insecticidal activity of the avermectins. 1980 Vet. Rec. pmid:7361432
Titchener RN and Purnell RE Duration of persistence of injectable avermectins against sucking lice of cattle. 1996 Vet. Rec. pmid:8903014
Gray AK Avermectin toxicity in the dog. 1997 Vet. Rec. pmid:9185316
Scarff DH Avermectin toxicity in the dog. 1997 Vet. Rec. pmid:9185317
Doody GM Avermectin toxicity in the dog. 1997 Vet. Rec. pmid:9203324
Hoste H et al. A questionnaire survey on the practices adopted to control gastrointestinal nematode parasitism in dairy goat farms in France. 2000 Vet. Res. Commun. pmid:11085466
Brayden DJ and Griffin J Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers. 2008 Vet. Res. Commun. pmid:17578674
Boukhrissa A et al. Study of the degradation in aqueous solution of a refractory organic compound: avermectin type used as pesticide in agriculture. 2017 Water Sci. Technol. pmid:29068328
Chen Z et al. [Effect of gene disruption of aveD on avermectins production in Streptomyces avermitilis]. 2001 Wei Sheng Wu Xue Bao pmid:12552909
Tao WX et al. [Cloning of bldAa and the effect on morphological differentiation and avermectins production in Streptomyces avermitilis NRRL8165]. 2007 Wei Sheng Wu Xue Bao pmid:17436620
Zhao X et al. Overexpression of metK shows different effects on avermectin production in various Streptomyces avermitilis strains. 2013 World J. Microbiol. Biotechnol. pmid:23579768
Li CL et al. [Differential acute mortality among the allozyme genotypes of Oxya chinensis by pesticide avermectin]. 2004 Yi Chuan Xue Bao pmid:15651676
He HG et al. [Resistance realized heritability and risk assessment of Panonychus citri to avermectin and fenpropathrin]. 2011 Ying Yong Sheng Tai Xue Bao pmid:22097380
Yang YN et al. [Avermectin poisoning in a child]. 2010 Zhongguo Dang Dai Er Ke Za Zhi pmid:20416232
Ji P et al. [Clinical analysis of acute Avermectins poisoning]. 2009 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi pmid:20039548
Wang XJ et al. [Effect of Avermectins on the secretion function of cultured granulosa cells from rat ovary in vitro.]. 2007 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi pmid:17945112
Liu GD et al. [Hemoperfusion in the treatment of an acute avermectin poisoning patient with liver cirrhosis]. 2012 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi pmid:22730696