| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dog Diseases | D004283 | 5 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Poisoning | D011041 | 9 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
| Fish Diseases | D005393 | 5 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xu Z et al. | From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. | 2017 | Toxicol. Sci. | pmid:27742867 |
| Boukhrissa A et al. | Study of the degradation in aqueous solution of a refractory organic compound: avermectin type used as pesticide in agriculture. | 2017 | Water Sci. Technol. | pmid:29068328 |
| Brownjohn PW et al. | Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease. | 2017 | Stem Cell Reports | pmid:28285880 |
| Kim MS et al. | Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis. | 2017 | Microb. Cell Fact. | pmid:28095865 |
| Mendes AM et al. | Inhibition of Plasmodium Liver Infection by Ivermectin. | 2017 | Antimicrob. Agents Chemother. | pmid:27895022 |
| Cui Q et al. | Avermectin biosynthesis: stable functional expression of branched chain α-keto acid dehydrogenase complex from Streptomyces avermitilis in Escherichia coli by selectively regulating individual subunit gene expression. | 2017 | Biotechnol. Lett. | pmid:28664314 |
| Zhang W et al. | Determination of avermectins by the internal standard recovery correction - high performance liquid chromatography - quantitative Nuclear Magnetic Resonance method. | 2017 | Talanta | pmid:28602306 |
| Silva GRD et al. | Multiresidue method for identification and quantification of avermectins, benzimidazoles and nitroimidazoles residues in bovine muscle tissue by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) using a QuEChERS approach. | 2017 | Talanta | pmid:28551144 |
| Mermans C et al. | A G326E substitution in the glutamate-gated chloride channel 3 (GluCl3) of the two-spotted spider mite Tetranychus urticae abolishes the agonistic activity of macrocyclic lactones. | 2017 | Pest Manag. Sci. | pmid:28736919 |
| Suroto DA et al. | Activation of cryptic phthoxazolin A production in Streptomyces avermitilis by the disruption of autoregulator-receptor homologue AvaR3. | 2017 | J. Biosci. Bioeng. | pmid:28728974 |
| Falkenberg LJ et al. | Low sensitivity of reproductive life-stages in the Pacific oyster (Crassostrea gigas) to abamectin. | 2017 | Chemosphere | pmid:28528312 |
| Zhang Y et al. | New Avermectin Analogues from a Mutant Streptomyces avermectinius Strain. | 2017 | Chem. Biodivers. | pmid:28387012 |
| Wang YS et al. | A spectrophotometric screening method for avermectin oxidizing microorganisms. | 2017 | J. Microbiol. Methods | pmid:28215961 |
| Liu C et al. | Avermectin induced global DNA hypomethylation and over-expression of heat shock proteins in cardiac tissues of pigeon. | 2017 | Pestic Biochem Physiol | pmid:28043331 |
| Tian P et al. | Comparative metabolomics reveals the mechanism of avermectin production enhancement by S-adenosylmethionine. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:27988821 |
| Iwai Y | Anecdote of the ÅŒmura laboratory and the discovery of avermectin. | 2017 | Biosci. Biotechnol. Biochem. | pmid:27885935 |
| Takahashi Y | Continuing fascination of exploration in natural substances from microorganisms. | 2017 | Biosci. Biotechnol. Biochem. | pmid:27885930 |
| Li M et al. | Effects of in vitro and in vivo avermectin exposure on alpha synuclein expression and proteasomal activity in pigeons. | 2017 | Ecotoxicol. Environ. Saf. | pmid:27677079 |
| Wang XS et al. | Autophagy response in the liver of pigeon exposed to avermectin. | 2017 | Environ Sci Pollut Res Int | pmid:26886445 |
| Qin Y et al. | Analysis of sulfonamides, tilmicosin and avermectins residues in typical animal matrices with multi-plug filtration cleanup by liquid chromatography-tandem mass spectrometry detection. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28410479 |