Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Dog Diseases D004283 5 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Fish Diseases D005393 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Fisher MH and Mrozik H The chemistry and pharmacology of avermectins. 1992 Annu. Rev. Pharmacol. Toxicol. pmid:1605577
Mosin VA et al. [Cytotoxic and cytostatic effect of avermectines on tumor cells in vitro]. 2000 Antibiot. Khimioter. pmid:11212393
Driniaev VA et al. [Selective cytostatic and cytotoxic effects of avermectins]. 2001 Antibiot. Khimioter. pmid:11558448
Driniaev VA et al. [Effect of avermectns on Ca(2+)-dependent chloride currents in plasmalemma of Chara corallina cells]. 2001 Antibiot. Khimioter. pmid:11558454
Viktorov AV et al. [Comparative analysis of degradation of native avermectins and spinosyns by UV-HPLC]. 2002 Antibiot. Khimioter. pmid:12728628
Driniaev VA et al. [Modification of antitumor effect of vincristine by natural avermectins]. 2004 Antibiot. Khimioter. pmid:15628794
Driniaev VA et al. [Antitumor effect of natural avermectins]. 2004 Antibiot. Khimioter. pmid:15573897
Sergeev AV et al. [Effect of nitrogen-containing compounds on the biosynthesis of avermectins]. 1995 Antibiot. Khimioter. pmid:8645056
Mironov VA et al. [Biosynthesis of avermectins: physiological and technological aspects]. 1997 Antibiot. Khimioter. pmid:9265465
Mosin VA et al. [Action of avermectins on lymphoid leukemia P-388 cells in vitro]. 1999 Antibiot. Khimioter. pmid:10422573