| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dog Diseases | D004283 | 5 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Poisoning | D011041 | 9 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
| Fish Diseases | D005393 | 5 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Avermectin A1a?
Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Avermectin A1a
PubChem Associated disorders and diseases
What pathways are associated with Avermectin A1a
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Avermectin A1a?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Avermectin A1a?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Avermectin A1a?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Avermectin A1a?
Related references are published most in these journals:
- Proc. Natl. Acad. Sci. U.S.A. (3)
- Appl. Environ. Microbiol. (3)
- J. Pharmacol. Exp. Ther. (1)
- Others (5)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Avermectin A1a?
Mouse Model
Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Avermectin A1a
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mosin VA et al. | [Cytotoxic and cytostatic effect of avermectines on tumor cells in vitro]. | 2000 | Antibiot. Khimioter. | pmid:11212393 |
| Mironov VA et al. | [Biosynthesis of avermectins: physiological and technological aspects]. | 1997 | Antibiot. Khimioter. | pmid:9265465 |
| Mendes AM et al. | Inhibition of Plasmodium Liver Infection by Ivermectin. | 2017 | Antimicrob. Agents Chemother. | pmid:27895022 |
| Haber CL et al. | Development of a mechanism of action-based screen for anthelmintic microbial metabolites with avermectinlike activity and isolation of milbemycin-producing Streptomyces strains. | 1991 | Antimicrob. Agents Chemother. | pmid:1719935 |
| Schulman MD et al. | Avermectin B2 O-methyltransferase activity in "Streptomyces avermitilis" mutants that produce increased amounts of the avermectins. | 1986 | Antimicrob. Agents Chemother. | pmid:3707112 |
| Ikeda H et al. | Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis. | 1988 | Antimicrob. Agents Chemother. | pmid:3364948 |
| Schulman MD et al. | "Streptomyces avermitilis" mutants defective in methylation of avermectins. | 1987 | Antimicrob. Agents Chemother. | pmid:3606074 |
| Schulman M et al. | Microbial conversion of avermectins by Saccharopolyspora erythraea: glycosylation at C-4' and C-4''. | 1993 | Antimicrob. Agents Chemother. | pmid:8239577 |
| Lim LE et al. | Anthelmintic avermectins kill Mycobacterium tuberculosis, including multidrug-resistant clinical strains. | 2013 | Antimicrob. Agents Chemother. | pmid:23165468 |
| Huang J et al. | Gene Replacement for the Generation of Designed Novel Avermectin Derivatives with Enhanced Acaricidal and Nematicidal Activities. | 2015 | Appl. Environ. Microbiol. | pmid:26025902 |