Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Dog Diseases D004283 5 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Fish Diseases D005393 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

Related references are published most in these journals:

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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Authors Title Published Journal PubMed Link
Danaher M et al. Development and optimisation of an improved derivatisation procedure for the determination of avermectins and milbemycins in bovine liver. 2001 Analyst pmid:11394296
Köhler P The biochemical basis of anthelmintic action and resistance. 2001 Int. J. Parasitol. pmid:11400692
Valenzuela AI et al. Comparison of various liquid chromatographic methods for the analysis of avermectin residues in citrus fruits. 2001 J Chromatogr A pmid:11403456
Drinyaev VA et al. Effect of avermectins on Ca2+-dependent Cl- currents in plasmalemma of Chara corallina cells. 2001 J. Membr. Biol. pmid:11426301
Wohlert S et al. Insights about the biosynthesis of the avermectin deoxysugar L-oleandrose through heterologous expression of Streptomyces avermitilis deoxysugar genes in Streptomyces lividans. 2001 Chem. Biol. pmid:11451669
Swarnkar CP et al. Anthelmintic resistance on an organized sheep farm in India. 2001 Trop Anim Health Prod pmid:11474864
Zakson-Aiken M et al. Systemic activity of the avermectins against the cat flea (Siphonaptera: Pulicidae). 2001 J. Med. Entomol. pmid:11476339
Anziani OS et al. Avermectin resistance in Cooperia pectinata in cattle in Argentina. 2001 Vet. Rec. pmid:11488345
Martins JR and Furlong J Avermectin resistance of the cattle tick Boophilus microplus in Brazil. 2001 Vet. Rec. pmid:11488352
Novik TS et al. [Acute toxicity of aversectin C : various routes of administration and dosage forms]. 2001 Mar-Apr Eksp Klin Farmakol pmid:11548452