Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Avermectin A1a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Avermectin A1a?

Avermectin A1a is suspected in Ataxia with vitamin E deficiency, Gigantism, Strongyloidiasis, Congenital Transposition, Onchocerciasis, Tropical Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Avermectin A1a

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Dog Diseases D004283 5 associated lipids
Leukemia P388 D007941 43 associated lipids
Neuroblastoma D009447 66 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Poisoning D011041 9 associated lipids
Cleft Palate D002972 9 associated lipids
Fish Diseases D005393 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Per page 10 20 | Total 19

PubChem Associated disorders and diseases

What pathways are associated with Avermectin A1a

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Avermectin A1a?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Avermectin A1a?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Avermectin A1a?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Avermectin A1a?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Avermectin A1a?

Mouse Model

Mouse Model are used in the study 'Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.' (Dawson GR et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Avermectin A1a

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Per page 10 20 50 100 | Total 477
Authors Title Published Journal PubMed Link
Lopatina IuV and Eremina OIu [Comparative activity of different groups of insecticides against permethrin-resistant lice (anoplura: pediculidae)]. 2013 Jan-Mar Med Parazitol (Mosk) pmid:23805484
McMahon C et al. Anthelmintic resistance in Northern Ireland (I): prevalence of resistance in ovine gastrointestinal nematodes, as determined through faecal egg count reduction testing. 2013 Vet. Parasitol. pmid:23398988
Park JH et al. Application of hollow-fiber-assisted liquid-phase microextraction to identify avermectins in stream water using MS/MS. 2013 J Sep Sci pmid:23504817
Sun P et al. Spiroketal formation and modification in avermectin biosynthesis involves a dual activity of AveC. 2013 J. Am. Chem. Soc. pmid:23294008
Yin P et al. Direct proteomic mapping of Streptomyces avermitilis wild and industrial strain and insights into avermectin production. 2013 J Proteomics pmid:23201115
Park JH et al. Development of an extraction method for the determination of avermectins in soil using supercritical CO2 modified with ethanol and liquid chromatography-tandem mass spectrometry. 2013 J Sep Sci pmid:23109286
Lim LE et al. Anthelmintic avermectins kill Mycobacterium tuberculosis, including multidrug-resistant clinical strains. 2013 Antimicrob. Agents Chemother. pmid:23165468
Yan Y et al. Utilization of environmental waste cyanobacteria as a pesticide carrier: studies on controlled release and photostability of avermectin. 2013 Colloids Surf B Biointerfaces pmid:23006573
Zhao X et al. Overexpression of metK shows different effects on avermectin production in various Streptomyces avermitilis strains. 2013 World J. Microbiol. Biotechnol. pmid:23579768
Luo L et al. Avermectin induces P-glycoprotein expression in S2 cells via the calcium/calmodulin/NF-κB pathway. 2013 Chem. Biol. Interact. pmid:23523950
Guo J et al. A novel TetR family transcriptional regulator, SAV576, negatively controls avermectin biosynthesis in Streptomyces avermitilis. 2013 PLoS ONE pmid:23967193
Liu Y et al. Characterization of SAV7471, a TetR-family transcriptional regulator involved in the regulation of coenzyme A metabolism in Streptomyces avermitilis. 2013 J. Bacteriol. pmid:23893108
Li M et al. Antioxidant response and histopathological changes in brain tissue of pigeon exposed to avermectin. 2013 Ecotoxicology pmid:23943211
Chen LJ et al. Avermectin induced inflammation damage in king pigeon brain. 2013 Chemosphere pmid:24134892
Zhu WJ et al. Avermectin induced liver injury in pigeon: mechanisms of apoptosis and oxidative stress. 2013 Ecotoxicol. Environ. Saf. pmid:24138898
Doan HT et al. The efficacy of avermectins (ivermectin, doramectin and abamectin) as treatments for infestation with the tick Haemaphysalis longicornis on rabbits in Korea. 2013 Vet. Parasitol. pmid:24140165
Komatsu M et al. Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites. 2013 ACS Synth Biol pmid:23654282
Beliavskaia LA et al. [Biologically active substances of preparation avercom]. 2012 May-Jun Mikrobiol. Z. pmid:22830191
Iutynska GO Elaboration of natural polyfunctional preparations with antiparasitic and biostimulating properties for plant growing. 2012 Jul-Aug Mikrobiol. Z. pmid:23088094
Erban T et al. The efficacy of four avermectins on the synanthropic mite Lepidoglyphus destructor under laboratory conditions. 2012 Exp. Appl. Acarol. pmid:22527833