Methymycin

Methymycin is a lipid of Polyketides (PK) class. Methymycin is associated with abnormalities such as abnormal fragmented structure. The involved functions are known as Anabolism.

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Introduction

To understand associated biological information of Methymycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Methymycin?

Methymycin is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Methymycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

What functions are associated with Methymycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Methymycin

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Authors Title Published Journal PubMed Link
Almutairi MM et al. Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. 2017 Nucleic Acids Res. pmid:28934499
Brzozowski RS and Wuest WM Twelve-membered macrolactones: privileged scaffolds for the development of new therapeutics. 2017 Chem Biol Drug Des pmid:27153932
Hansen DA et al. Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. 2013 J. Am. Chem. Soc. pmid:23866020
Akhmedov NG et al. A conformational NMR analysis of methymycin aglycones: complete and unambiguous assignments of stereochemically diverse glycosylated methymycin analogs by 1D and 2D NMR techniques and molecular modeling. 2013 Magn Reson Chem pmid:23364799
Ding R et al. New methymycin derivatives of Streptomyces venezuelae ATCC 15439 and their inhibitory effects on human T cell proliferation mediated by PMA/ionomycin. 2012 Arch. Pharm. Res. pmid:23054713
Borisova SA and Liu HW Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway. 2010 Biochemistry pmid:20695498
Borisova SA et al. A de novo approach to the synthesis of glycosylated methymycin analogues with structural and stereochemical diversity. 2010 Org. Lett. pmid:20958086
Kittendorf JD and Sherman DH The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis. 2009 Bioorg. Med. Chem. pmid:19027305
Oh HS et al. Total synthesis of methymycin. 2009 Org. Biomol. Chem. pmid:19830295
Sadeghi-Khomami A et al. Glycosidase inhibition by macrolide antibiotics elucidated by STD-NMR spectroscopy. 2008 Chem. Biol. pmid:18635010