Methymycin

Methymycin is a lipid of Polyketides (PK) class. Methymycin is associated with abnormalities such as abnormal fragmented structure. The involved functions are known as Anabolism.

Cross Reference

Introduction

To understand associated biological information of Methymycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Methymycin?

Methymycin is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Methymycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

What functions are associated with Methymycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Methymycin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Methymycin

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Authors Title Published Journal PubMed Link
pmid:
Vilches C et al. Role of glycosylation and deglycosylation in biosynthesis of and resistance to oleandomycin in the producer organism, Streptomyces antibioticus. 1992 J. Bacteriol. pmid:1530845
Lambalot RH and Cane DE Isolation and characterization of 10-deoxymethynolide produced by Streptomyces venezuelae. 1992 J. Antibiot. pmid:1490892
Graziani EI et al. Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae. 1998 Bioorg. Med. Chem. Lett. pmid:9873687
Tang L et al. Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase. 1999 Chem. Biol. pmid:10421766
Xue Y et al. Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides. 2000 Gene pmid:10713461
Xue Y and Sherman DH Alternative modular polyketide synthase expression controls macrolactone structure. 2000 Nature pmid:10676969
Chen S et al. The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide. 2001 Gene pmid:11223265
Zhang Q and Sherman DH Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae. 2001 J. Nat. Prod. pmid:11720530
Chang CW and Liu HW Synthesis of TDP-3-amino-3,4,6-trideoxy-alpha-D-xylo-hexopyranose--the immediate precursor of TDP-alpha-D-desosamine. 2002 Bioorg. Med. Chem. Lett. pmid:12031327