| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Almutairi MM et al. | Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. | 2017 | Nucleic Acids Res. | pmid:28934499 |
| Brzozowski RS and Wuest WM | Twelve-membered macrolactones: privileged scaffolds for the development of new therapeutics. | 2017 | Chem Biol Drug Des | pmid:27153932 |
| Hansen DA et al. | Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. | 2013 | J. Am. Chem. Soc. | pmid:23866020 |
| Akhmedov NG et al. | A conformational NMR analysis of methymycin aglycones: complete and unambiguous assignments of stereochemically diverse glycosylated methymycin analogs by 1D and 2D NMR techniques and molecular modeling. | 2013 | Magn Reson Chem | pmid:23364799 |
| Ding R et al. | New methymycin derivatives of Streptomyces venezuelae ATCC 15439 and their inhibitory effects on human T cell proliferation mediated by PMA/ionomycin. | 2012 | Arch. Pharm. Res. | pmid:23054713 |
| Borisova SA and Liu HW | Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway. | 2010 | Biochemistry | pmid:20695498 |
| Borisova SA et al. | A de novo approach to the synthesis of glycosylated methymycin analogues with structural and stereochemical diversity. | 2010 | Org. Lett. | pmid:20958086 |
| Kittendorf JD and Sherman DH | The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis. | 2009 | Bioorg. Med. Chem. | pmid:19027305 |
| Oh HS et al. | Total synthesis of methymycin. | 2009 | Org. Biomol. Chem. | pmid:19830295 |
| Sadeghi-Khomami A et al. | Glycosidase inhibition by macrolide antibiotics elucidated by STD-NMR spectroscopy. | 2008 | Chem. Biol. | pmid:18635010 |
| Kao CL et al. | Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications. | 2006 | J. Am. Chem. Soc. | pmid:16637606 |
| Giraldes JW et al. | Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels. | 2006 | Nat. Chem. Biol. | pmid:16969373 |
| He W et al. | Macrolactonization to 10-deoxymethynolide catalyzed by the recombinant thioesterase of the picromycin/methymycin polyketide synthase. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16249083 |
| Wu J et al. | Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/methymycin polyketide synthase. | 2005 | J. Am. Chem. Soc. | pmid:16332089 |
| Wu J et al. | Chain elongation, macrolactonization, and hydrolysis of natural and reduced hexaketide substrates by the picromycin/methymycin polyketide synthase. | 2005 | Angew. Chem. Int. Ed. Engl. | pmid:16247819 |
| Srinivasan A et al. | Bacterial P450-catalyzed polyketide hydroxylation on a microfluidic platform. | 2004 | Biotechnol. Bioeng. | pmid:15459906 |
| Borisova SA et al. | Characterization of the glycosyltransferase activity of desVII: analysis of and implications for the biosynthesis of macrolide antibiotics. | 2004 | J. Am. Chem. Soc. | pmid:15161264 |
| Hong JS et al. | New olivosyl derivatives of methymycin/pikromycin from an engineered strain of Streptomyces venezuelae. | 2004 | FEMS Microbiol. Lett. | pmid:15358425 |
| Yin Y et al. | Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase. | 2003 | J. Am. Chem. Soc. | pmid:12733905 |
| Zhao L et al. | Beta-glucosylation as a part of self-resistance mechanism in methymycin/pikromycin producing strain Streptomyces venezuelae. | 2003 | Biochemistry | pmid:14674753 |
Methymycin
Methymycin is a lipid of Polyketides (PK) class. Methymycin is associated with abnormalities such as abnormal fragmented structure. The involved functions are known as Anabolism.
Cross Reference
Introduction
To understand associated biological information of Methymycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Methymycin?
Methymycin is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Methymycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Methymycin?
There are no associated biomedical information in the current reference collection.
What functions are associated with Methymycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Methymycin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Methymycin?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Methymycin?
There are no associated biomedical information in the current reference collection.