Pikromycin

Pikromycin is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Process, Cytokinesis, Mutation and Biochemical Pathway. Pikromycin often locates in soluble. The associated genes with Pikromycin are SLC7A1 gene, Homologous Gene, Gene Clusters, Polypeptides and THEMIS gene.

Cross Reference

Introduction

To understand associated biological information of Pikromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Pikromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pikromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pikromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Pikromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pikromycin

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Authors Title Published Journal PubMed Link
pmid:
BRODERSEN R et al. Antibiotic properties of picromycin. 1953 Acta Pharmacol Toxicol (Copenh) pmid:13123945
Betlach MC et al. Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin. 1998 Biochemistry pmid:9778370
Graziani EI et al. Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae. 1998 Bioorg. Med. Chem. Lett. pmid:9873687
Tang L et al. Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase. 1999 Chem. Biol. pmid:10421766
Xue Y et al. Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides. 2000 Gene pmid:10713461
Xue Y and Sherman DH Alternative modular polyketide synthase expression controls macrolactone structure. 2000 Nature pmid:10676969
Tang L et al. Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases. 2000 Chem. Biol. pmid:10662693
Chen S et al. Mechanisms of molecular recognition in the pikromycin polyketide synthase. 2000 Chem. Biol. pmid:11137814
Garzotti M et al. Coupling of a supercritical fluid chromatography system to a hybrid (Q-TOF 2) mass spectrometer: on-line accurate mass measurements. 2001 Rapid Commun. Mass Spectrom. pmid:11445901