| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hansen DA et al. | Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides. | 2017 | J. Am. Chem. Soc. | pmid:28836772 |
| Koch AA et al. | A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst. | 2017 | J. Am. Chem. Soc. | pmid:28836768 |
| Pyeon HR et al. | Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system. | 2017 | Microb. Cell Fact. | pmid:28569150 |
| Han S et al. | Structural insights into the binding of lauric acid to CYP107L2 from Streptomyces avermitilis. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27890614 |
| Goldberg VE et al. | Assessment of Erythroid and Granulocytic Hematopoietic Lineages in Patients with Non-Small-Cell Lung Carcinoma. | 2017 | Bull. Exp. Biol. Med. | pmid:28853075 |
| Almutairi MM et al. | Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. | 2017 | Nucleic Acids Res. | pmid:28934499 |
| Tripathi A et al. | Thioesterase domain swapping of a linear polyketide tautomycetin with a macrocyclic polyketide pikromycin in Streptomyces sp. CK4412. | 2016 | J. Ind. Microbiol. Biotechnol. | pmid:27277081 |
| Chemler JA et al. | Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. | 2015 | J. Am. Chem. Soc. | pmid:26230368 |
| Li Y et al. | Functional Characterization of a Dehydratase Domain from the Pikromycin Polyketide Synthase. | 2015 | J. Am. Chem. Soc. | pmid:26027428 |
| Hansen DA et al. | Substrate controlled divergence in polyketide synthase catalysis. | 2015 | J. Am. Chem. Soc. | pmid:25730816 |
| Yi JS et al. | Effects of Sucrose, Phosphate, and Calcium Carbonate on the Production of Pikromycin from Streptomyces venezuelae. | 2015 | J. Microbiol. Biotechnol. | pmid:25341465 |
| Dutta S et al. | Structure of a modular polyketide synthase. | 2014 | Nature | pmid:24965652 |
| Whicher JR et al. | Structural rearrangements of a polyketide synthase module during its catalytic cycle. | 2014 | Nature | pmid:24965656 |
| Hansen DA et al. | Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. | 2013 | J. Am. Chem. Soc. | pmid:23866020 |
| Oh HS and Kang HY | Total synthesis of pikromycin. | 2012 | J. Org. Chem. | pmid:22168449 |
| Bonnett SA et al. | Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS. | 2011 | Chem. Biol. | pmid:21944746 |
| Han AR et al. | Biosynthesis of glycosylated derivatives of tylosin in Streptomyces venezuelae. | 2011 | J. Microbiol. Biotechnol. | pmid:21715968 |
| Borisova SA and Liu HW | Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway. | 2010 | Biochemistry | pmid:20695498 |
| Mortison JD et al. | Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases. | 2009 | J. Am. Chem. Soc. | pmid:19810731 |
| Buchholz TJ et al. | Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. | 2009 | ACS Chem. Biol. | pmid:19146481 |
Pikromycin
Pikromycin is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Process, Cytokinesis, Mutation and Biochemical Pathway. Pikromycin often locates in soluble. The associated genes with Pikromycin are SLC7A1 gene, Homologous Gene, Gene Clusters, Polypeptides and THEMIS gene.
Cross Reference
Introduction
To understand associated biological information of Pikromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pikromycin?
There are no associated biomedical information in the current reference collection.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Pikromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pikromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pikromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pikromycin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Pikromycin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Pikromycin?
There are no associated biomedical information in the current reference collection.