|
|
|
|
pmid:
|
Havens CG et al. |
Cellular effects of leishmanial tubulin inhibitors on L. donovani. |
2000 |
Mol. Biochem. Parasitol. |
pmid:11071278
|
Carroll BJ et al. |
Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. |
2002 |
J. Am. Chem. Soc. |
pmid:11960423
|
Moss SJ et al. |
Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate. |
2002 |
J. Am. Chem. Soc. |
pmid:12047169
|
Yu TW et al. |
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12060743
|
Spiteller P et al. |
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum. |
2003 |
J. Am. Chem. Soc. |
pmid:14624546
|
Okamoto K et al. |
Therapeutic effect of ansamitocin targeted to tumor by a bispecific monoclonal antibody. |
1992 |
Jpn. J. Cancer Res. |
pmid:1517150
|
Lu C et al. |
A novel amide N-glycoside of ansamitocins from Actinosynnema pretiosum. |
2004 |
J. Antibiot. |
pmid:15303496
|
Li Y et al. |
Binding selectivity of rhizoxin, phomopsin A, vinblastine, and ansamitocin P-3 to fungal tubulins: differential interactions of these antimitotic agents with brain and fungal tubulins. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1530630
|
Liu Z et al. |
An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics. |
2004 |
J Pharm Biomed Anal |
pmid:15533675
|
Liu Z et al. |
Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. |
2005 |
J Mass Spectrom |
pmid:15674857
|
Kubota T et al. |
Determination of the cryptic stereochemistry of the first PKS chain-extension step in ansamitocin biosynthesis by Actinosynnema pretiosum. |
2006 |
Chembiochem |
pmid:16927319
|
Wenzel SC et al. |
On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A. |
2006 |
J. Am. Chem. Soc. |
pmid:17076505
|
Li Y et al. |
Interaction of phomopsin A with porcine brain tubulin. Inhibition of tubulin polymerization and binding at a rhizoxin binding site. |
1992 |
Biochem. Pharmacol. |
pmid:1739410
|
Ma J et al. |
New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum. |
2007 |
Arch. Pharm. Res. |
pmid:17679541
|
Snipes CE et al. |
The ansacarbamitocins: polar ansamitocin derivatives. |
2007 |
J. Nat. Prod. |
pmid:17892263
|
Goh S et al. |
An integrative expression vector for Actinosynnema pretiosum. |
2007 |
BMC Biotechnol. |
pmid:17956638
|
Taft F et al. |
Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant. |
2008 |
Chembiochem |
pmid:18381586
|
Zhao P et al. |
Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins. |
2008 |
Chem. Biol. |
pmid:18721757
|
Taft F et al. |
Timing of the Delta(10,12)-Delta(11,13) double bond migration during ansamitocin biosynthesis in Actinosynnema pretiosum. |
2009 |
J. Am. Chem. Soc. |
pmid:19292483
|