Ansamitocin P-3

Ansamitocin P-3 is a lipid of Polyketides (PK) class.

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Current reference collection contains 418 references associated with Ansamitocin P-3 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Du ZQ et al. Combination of traditional mutation and metabolic engineering to enhance ansamitocin P-3 production in Actinosynnema pretiosum. 2017 Biotechnol. Bioeng. pmid:28782796
Zhao M et al. Effects of the Methylmalonyl-CoA Metabolic Pathway on Ansamitocin Production in Actinosynnema pretiosum. 2017 Appl. Biochem. Biotechnol. pmid:27787765
Seidel K et al. Synthesis of Magnetic-Nanoparticle/Ansamitocin Conjugates-Inductive Heating Leads to Decreased Cell Proliferation In Vitro and Attenuation Of Tumour Growth In Vivo. 2017 Chemistry pmid:28585348
Wang LL et al. A Bio-Chemosynthetic Approach to Superparamagnetic Iron Oxide-Ansamitocin Conjugates for Use in Magnetic Drug Targeting. 2017 Chemistry pmid:27935144
Ning X et al. Identification and Engineering of Post-PKS Modification Bottlenecks for Ansamitocin P-3 Titer Improvement in Actinosynnema pretiosum subsp. pretiosum ATCC 31280. 2017 Biotechnol J pmid:28881098
Lin J and Zhong JJ Proteomic studies on anti-tumor agent ansamitocin P-3 producer Actinosynnema pretiosum in response to ammonium and isobutanol. 2017 Bioprocess Biosyst Eng pmid:28382459
Fan Y et al. Effects of modulation of pentose-phosphate pathway on biosynthesis of ansamitocins in Actinosynnema pretiosum. 2016 J. Biotechnol. pmid:27173582
Fan Y et al. Enhancement of UDPG synthetic pathway improves ansamitocin production in Actinosynnem pretiosum. 2016 Appl. Microbiol. Biotechnol. pmid:26585444
Li S et al. Constitutive overexpression of asm18 increases the production and diversity of maytansinoids in Actinosynnema pretiosum. 2016 Appl. Microbiol. Biotechnol. pmid:26572523
Zhang YG et al. Nocardiopsis ansamitocini sp. nov., a new producer of ansamitocin P-3 of the genus Nocardiopsis. 2016 Int. J. Syst. Evol. Microbiol. pmid:26486850
Li T et al. Improvement of ansamitocin P-3 production by Actinosynnema mirum with fructose as the sole carbon source. 2015 Appl. Biochem. Biotechnol. pmid:25564203
Fan Y et al. Process optimization with alternative carbon sources and modulation of secondary metabolism for enhanced ansamitocin P-3 production in Actinosynnema pretiosum. 2014 J. Biotechnol. pmid:25456055
Mancuso L et al. Preparation of thermocleavable conjugates based on ansamitocin and superparamagnetic nanostructured particles by a chemobiosynthetic approach. 2014 Chemistry pmid:25346489
Martin K et al. The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity. 2014 Cancer Immunol. Immunother. pmid:24906866
Gao Y et al. Enhancement of ansamitocin P-3 production in Actinosynnema pretiosum by a synergistic effect of glycerol and glucose. 2014 J. Ind. Microbiol. Biotechnol. pmid:24174216
Venghateri JB et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. 2013 PLoS ONE pmid:24124473
Dagger F et al. Regulatory volume decrease in Leishmania mexicana: effect of anti-microtubule drugs. 2013 Mem. Inst. Oswaldo Cruz pmid:23440120
Pan W et al. Asm8, a specific LAL-type activator of 3-amino-5-hydroxybenzoate biosynthesis in ansamitocin production. 2013 Sci China Life Sci pmid:23832249
Siyu-Mao et al. Two novel ansamitocin analogs from Actinosynnema pretiosum. 2013 Nat. Prod. Res. pmid:23061718
Mancuso L et al. Bioreduction of aryl azides during mutasynthesis of new ansamitocins. 2013 Org. Lett. pmid:23981134

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