| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
Total
3
Epothilone A
Epothilone a is a lipid of Polyketides (PK) class. Epothilone a is associated with abnormalities such as abnormal fragmented structure and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Polymerization, Mutation, Depolymerization, Musculoskeletal torsion, function and Negative Regulation of Microtubule Depolymerization. Epothilone a often locates in Microtubules, soluble, Nuclear Structure and Microtubule cytoskeleton. The associated genes with Epothilone A are C9 gene, SLC33A1 gene, KIF2C gene and HMHA1 gene.
Cross Reference
Introduction
To understand associated biological information of Epothilone A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Epothilone A?
Epothilone A is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Epothilone A
PubChem Associated disorders and diseases
What pathways are associated with Epothilone A
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Epothilone A?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Epothilone A?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Epothilone A?
There are no associated biomedical information in the current reference collection.
What genes are associated with Epothilone A?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Epothilone A?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Epothilone A
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schinzer D et al. | Synthesis and biological evaluation of aza-epothilones. | 2000 | Chembiochem | pmid:11828400 |
| Liu ZY et al. | Total synthesis of epothilone a through stereospecific epoxidation of the p-methoxybenzyl ether of epothilone C. | 2002 | Chemistry | pmid:12203301 |
| Martello LA et al. | Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines. | 2000 | Clin. Cancer Res. | pmid:10815923 |
| Stachel SJ et al. | The epothilones, eleutherobins, and related types of molecules. | 2001 | Curr. Pharm. Des. | pmid:11472267 |
| Yu D et al. | Mechanical and functional properties of epothilone-stabilized microtubules. | 2013 | Cytoskeleton (Hoboken) | pmid:23135951 |
| Kavallaris M et al. | Anticancer therapy with novel tubulin-interacting drugs. | 2001 | Drug Resist. Updat. | pmid:12030786 |
| Borrelli S et al. | New class of squalene-based releasable nanoassemblies of paclitaxel, podophyllotoxin, camptothecin and epothilone A. | 2014 | Eur J Med Chem | pmid:25084144 |
| Taraschi TF et al. | Plasmodium falciparum: characterization of organelle migration during merozoite morphogenesis in asexual malaria infections. | 1998 | Exp. Parasitol. | pmid:9562421 |
| Santi DV et al. | An approach for obtaining perfect hybridization probes for unknown polyketide synthase genes: a search for the epothilone gene cluster. | 2000 | Gene | pmid:10773448 |
| Parajuli P et al. | Enzymatic synthesis of lactosylated and sialylated derivatives of epothilone A. | 2016 | Glycoconj. J. | pmid:26852037 |