Nystatin A3

Nystatin A3 is a lipid of Polyketides (PK) class. Nystatin a3 is associated with abnormalities such as Mycoses, Candidiasis of the genitals and Gigantism. The involved functions are known as Drug Interactions, Process, Synthesis, Fermentation and Anabolism. Nystatin a3 often locates in Cell membrane, Membrane, Protoplasm, Entire oral cavity and integral to membrane. The associated genes with Nystatin A3 are Gene Clusters. The related lipids are Sterols, 1,2-oleoylphosphatidylcholine, Membrane Lipids, DOPE and N-caproylsphingosine.

Cross Reference

Introduction

To understand associated biological information of Nystatin A3, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Nystatin A3?

Nystatin A3 is suspected in Mycoses, Candidiasis of the genitals, Gigantism and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Nystatin A3

MeSH term MeSH ID Detail
Candidemia D058387 2 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Xerostomia D014987 6 associated lipids
Vaginitis D014627 6 associated lipids
Urethritis D014526 9 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Peritonitis D010538 38 associated lipids
Otitis Externa D010032 8 associated lipids
Mycoses D009181 18 associated lipids
Leishmaniasis D007896 19 associated lipids
Influenza, Human D007251 11 associated lipids
Hypertension D006973 115 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hemolysis D006461 131 associated lipids
Gonorrhea D006069 7 associated lipids
Dermatomycoses D003881 17 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Candidiasis, Vulvovaginal D002181 8 associated lipids
Candidiasis, Oral D002180 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Nystatin A3

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Nystatin A3?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Nystatin A3?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Nystatin A3?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Nystatin A3?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Nystatin A3?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Nystatin A3

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Per page 10 20 50 100 | Total 1594
Authors Title Published Journal PubMed Link
Johnson EM et al. Comparison of in vitro antifungal activities of free and liposome-encapsulated nystatin with those of four amphotericin B formulations. 1998 Antimicrob. Agents Chemother. pmid:9624486
Groll AH et al. Safety and efficacy of multilamellar liposomal nystatin against disseminated candidiasis in persistently neutropenic rabbits. 1999 Antimicrob. Agents Chemother. pmid:10508025
Ramaswamy M et al. Species differences in the proportion of plasma lipoprotein lipid carried by high-density lipoproteins influence the distribution of free and liposomal nystatin in human, dog, and rat plasma. 1999 Antimicrob. Agents Chemother. pmid:10348764
Mehta RT et al. Formulation, toxicity, and antifungal activity in vitro of liposome-encapsulated nystatin as therapeutic agent for systemic candidiasis. 1987 Antimicrob. Agents Chemother. pmid:3439798
Mehta RT et al. Toxicity and therapeutic effects in mice of liposome-encapsulated nystatin for systemic fungal infections. 1987 Antimicrob. Agents Chemother. pmid:3439799
Ostrosky-Zeichner L et al. Differential antifungal activity of isomeric forms of nystatin. 2001 Antimicrob. Agents Chemother. pmid:11557469
Clements-Jewery S Nystatin-induced potassium efflux from Saccharomyces cerevisiae measured by flame photometry: a potential bioassay approach. 1976 Antimicrob. Agents Chemother. pmid:773299
Hsuchen CC and Feingold DS Selective membrane toxicity of the polyene antibiotics: studies on natural membranes. 1973 Antimicrob. Agents Chemother. pmid:4586145
Meletiadis J et al. In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates. 2002 Antimicrob. Agents Chemother. pmid:11751112
Hsuchen CC and Feingold DS Selective membrane toxicity of the polyene antibiotics: studies on lecithin membrane models (liposomes). 1973 Antimicrob. Agents Chemother. pmid:4758835
Tevyashova AN et al. Structure-antifungal activity relationships of polyene antibiotics of the amphotericin B group. 2013 Antimicrob. Agents Chemother. pmid:23716057
Badaracco G and Cassani G Ribonucleic acid synthesis dependent on exogenous triphosphates in nystatin-treated cells of of Kluyveromyces latis. 1976 Antimicrob. Agents Chemother. pmid:949173
Segal E et al. Susceptibility of Prototheca species to antifungal agents. 1976 Antimicrob. Agents Chemother. pmid:984758
Flattery AM et al. New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents. 1996 Antimicrob. Agents Chemother. pmid:8807048
Brass C et al. Variability of agar dilution-replicator method of yeast susceptibility testing. 1979 Antimicrob. Agents Chemother. pmid:573098
Sletta H et al. Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin. 2005 Antimicrob. Agents Chemother. pmid:16251298
Akiyama S et al. Classification of polyene antibiotics according to their synergistic effect in combination with bleomycin A2 or fusidic acid. 1980 Antimicrob. Agents Chemother. pmid:6160808
Groll AH et al. Comparative drug disposition, urinary pharmacokinetics, and renal effects of multilamellar liposomal nystatin and amphotericin B deoxycholate in rabbits. 2003 Antimicrob. Agents Chemother. pmid:14638502
Oakley KL et al. Comparison of in vitro activity of liposomal nystatin against Aspergillus species with those of nystatin, amphotericin B (AB) deoxycholate, AB colloidal dispersion, liposomal AB, AB lipid complex, and itraconazole. 1999 Antimicrob. Agents Chemother. pmid:10223948
Cassidy SM et al. Plasma lipoprotein distribution of liposomal nystatin is influenced by protein content of high-density lipoproteins. 1998 Antimicrob. Agents Chemother. pmid:9687378