Nystatin A3 is a lipid of Polyketides (PK) class. Nystatin a3 is associated with abnormalities such as Mycoses, Candidiasis of the genitals and Gigantism. The involved functions are known as Drug Interactions, Process, Synthesis, Fermentation and Anabolism. Nystatin a3 often locates in Cell membrane, Membrane, Protoplasm, Entire oral cavity and integral to membrane. The associated genes with Nystatin A3 are Gene Clusters. The related lipids are Sterols, 1,2-oleoylphosphatidylcholine, Membrane Lipids, DOPE and N-caproylsphingosine.
To understand associated biological information of Nystatin A3, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Nystatin A3 is suspected in Mycoses, Candidiasis of the genitals, Gigantism and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Nystatin A3
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Johnson EM et al. | Comparison of in vitro antifungal activities of free and liposome-encapsulated nystatin with those of four amphotericin B formulations. | 1998 | Antimicrob. Agents Chemother. | pmid:9624486 |
Denning DW and Warn P | Dose range evaluation of liposomal nystatin and comparisons with amphotericin B and amphotericin B lipid complex in temporarily neutropenic mice infected with an isolate of Aspergillus fumigatus with reduced susceptibility to amphotericin B. | 1999 | Antimicrob. Agents Chemother. | pmid:10543734 |
Cosgrove RF and Fairbrother JE | Bioassay method for polyene antibiotics based on the measurement of rubidium efflux from rubidium-loaded yeast cells. | 1977 | Antimicrob. Agents Chemother. | pmid:319752 |
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González GM et al. | In vitro activities of free and lipid formulations of amphotericin B and nystatin against clinical isolates of Coccidioides immitis at various saprobic stages. | 2002 | Antimicrob. Agents Chemother. | pmid:11959606 |
Gunderson SM et al. | In vitro pharmacodynamic characteristics of nystatin including time-kill and postantifungal effect. | 2000 | Antimicrob. Agents Chemother. | pmid:10991881 |
Kasbekar DP et al. | Self-induced nystatin resistance in Dictyostelium discoideum. | 1985 | Antimicrob. Agents Chemother. | pmid:4026273 |
Boyce ST et al. | Noncytotoxic combinations of topical antimicrobial agents for use with cultured skin substitutes. | 1995 | Antimicrob. Agents Chemother. | pmid:7574524 |
Venables P and Russell AD | Nystatin-induced changes in Saccharomyces cerevisiae. | 1975 | Antimicrob. Agents Chemother. | pmid:1094947 |
Randhawa P et al. | BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport. | 2007 | Antimicrob. Agents Chemother. | pmid:17893158 |
Tevyashova AN et al. | Structure-antifungal activity relationships of polyene antibiotics of the amphotericin B group. | 2013 | Antimicrob. Agents Chemother. | pmid:23716057 |
Segal E et al. | Susceptibility of Prototheca species to antifungal agents. | 1976 | Antimicrob. Agents Chemother. | pmid:984758 |
Groll AH et al. | Compartmental pharmacokinetics and tissue distribution of multilamellar liposomal nystatin in rabbits. | 2000 | Antimicrob. Agents Chemother. | pmid:10722496 |
Walker-Caprioglio HM et al. | Antibodies to nystatin demonstrate polyene sterol specificity and allow immunolabeling of sterols in Saccharomyces cerevisiae. | 1989 | Antimicrob. Agents Chemother. | pmid:2694950 |
Wasan KM et al. | Physical characteristics and lipoprotein distribution of liposomal nystatin in human plasma. | 1997 | Antimicrob. Agents Chemother. | pmid:9303376 |
Wallace TL et al. | Activity of liposomal nystatin against disseminated Aspergillus fumigatus infection in neutropenic mice. | 1997 | Antimicrob. Agents Chemother. | pmid:9333054 |
Sletta H et al. | Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin. | 2005 | Antimicrob. Agents Chemother. | pmid:16251298 |
Razonable RR et al. | Nystatin induces secretion of interleukin (IL)-1beta, IL-8, and tumor necrosis factor alpha by a toll-like receptor-dependent mechanism. | 2005 | Antimicrob. Agents Chemother. | pmid:16048981 |
Groll AH et al. | Comparative drug disposition, urinary pharmacokinetics, and renal effects of multilamellar liposomal nystatin and amphotericin B deoxycholate in rabbits. | 2003 | Antimicrob. Agents Chemother. | pmid:14638502 |