Nystatin A3 is a lipid of Polyketides (PK) class. Nystatin a3 is associated with abnormalities such as Mycoses, Candidiasis of the genitals and Gigantism. The involved functions are known as Drug Interactions, Process, Synthesis, Fermentation and Anabolism. Nystatin a3 often locates in Cell membrane, Membrane, Protoplasm, Entire oral cavity and integral to membrane. The associated genes with Nystatin A3 are Gene Clusters. The related lipids are Sterols, 1,2-oleoylphosphatidylcholine, Membrane Lipids, DOPE and N-caproylsphingosine.
To understand associated biological information of Nystatin A3, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Nystatin A3 is suspected in Mycoses, Candidiasis of the genitals, Gigantism and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Nystatin A3
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Denning DW and Warn P | Dose range evaluation of liposomal nystatin and comparisons with amphotericin B and amphotericin B lipid complex in temporarily neutropenic mice infected with an isolate of Aspergillus fumigatus with reduced susceptibility to amphotericin B. | 1999 | Antimicrob. Agents Chemother. | pmid:10543734 |
Groll AH et al. | Safety and efficacy of multilamellar liposomal nystatin against disseminated candidiasis in persistently neutropenic rabbits. | 1999 | Antimicrob. Agents Chemother. | pmid:10508025 |
Meletiadis J et al. | In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates. | 2002 | Antimicrob. Agents Chemother. | pmid:11751112 |
Hsuchen CC and Feingold DS | Selective membrane toxicity of the polyene antibiotics: studies on lecithin membrane models (liposomes). | 1973 | Antimicrob. Agents Chemother. | pmid:4758835 |
Badaracco G and Cassani G | Ribonucleic acid synthesis dependent on exogenous triphosphates in nystatin-treated cells of of Kluyveromyces latis. | 1976 | Antimicrob. Agents Chemother. | pmid:949173 |
Walker-Caprioglio HM et al. | Antibodies to nystatin demonstrate polyene sterol specificity and allow immunolabeling of sterols in Saccharomyces cerevisiae. | 1989 | Antimicrob. Agents Chemother. | pmid:2694950 |
Brass C et al. | Variability of agar dilution-replicator method of yeast susceptibility testing. | 1979 | Antimicrob. Agents Chemother. | pmid:573098 |
Sletta H et al. | Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin. | 2005 | Antimicrob. Agents Chemother. | pmid:16251298 |
Razonable RR et al. | Nystatin induces secretion of interleukin (IL)-1beta, IL-8, and tumor necrosis factor alpha by a toll-like receptor-dependent mechanism. | 2005 | Antimicrob. Agents Chemother. | pmid:16048981 |
Groll AH et al. | Comparative drug disposition, urinary pharmacokinetics, and renal effects of multilamellar liposomal nystatin and amphotericin B deoxycholate in rabbits. | 2003 | Antimicrob. Agents Chemother. | pmid:14638502 |