Nystatin A3

Nystatin A3 is a lipid of Polyketides (PK) class. Nystatin a3 is associated with abnormalities such as Mycoses, Candidiasis of the genitals and Gigantism. The involved functions are known as Drug Interactions, Process, Synthesis, Fermentation and Anabolism. Nystatin a3 often locates in Cell membrane, Membrane, Protoplasm, Entire oral cavity and integral to membrane. The associated genes with Nystatin A3 are Gene Clusters. The related lipids are Sterols, 1,2-oleoylphosphatidylcholine, Membrane Lipids, DOPE and N-caproylsphingosine.

Cross Reference

Introduction

To understand associated biological information of Nystatin A3, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Nystatin A3?

Nystatin A3 is suspected in Mycoses, Candidiasis of the genitals, Gigantism and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Nystatin A3

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hypertension D006973 115 associated lipids
Influenza, Human D007251 11 associated lipids
Leishmaniasis D007896 19 associated lipids
Mycoses D009181 18 associated lipids
Otitis Externa D010032 8 associated lipids
Peritonitis D010538 38 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Urethritis D014526 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Nystatin A3

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Nystatin A3?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Nystatin A3?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Nystatin A3?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Nystatin A3?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Nystatin A3?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Nystatin A3

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Per page 10 20 50 100 | Total 1594
Authors Title Published Journal PubMed Link
Denning DW and Warn P Dose range evaluation of liposomal nystatin and comparisons with amphotericin B and amphotericin B lipid complex in temporarily neutropenic mice infected with an isolate of Aspergillus fumigatus with reduced susceptibility to amphotericin B. 1999 Antimicrob. Agents Chemother. pmid:10543734
Cosgrove RF and Fairbrother JE Bioassay method for polyene antibiotics based on the measurement of rubidium efflux from rubidium-loaded yeast cells. 1977 Antimicrob. Agents Chemother. pmid:319752
Groll AH et al. Safety and efficacy of multilamellar liposomal nystatin against disseminated candidiasis in persistently neutropenic rabbits. 1999 Antimicrob. Agents Chemother. pmid:10508025
Alonso MA et al. Compounds affecting membranes that inhibit protein synthesis in yeast. 1979 Antimicrob. Agents Chemother. pmid:394675
Lees ND et al. Azole susceptibility and hyphal formation in a cytochrome P-450-deficient mutant of Candida albicans. 1990 Antimicrob. Agents Chemother. pmid:2193620
Meletiadis J et al. In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates. 2002 Antimicrob. Agents Chemother. pmid:11751112
González GM et al. In vitro activities of free and lipid formulations of amphotericin B and nystatin against clinical isolates of Coccidioides immitis at various saprobic stages. 2002 Antimicrob. Agents Chemother. pmid:11959606
Hsuchen CC and Feingold DS Selective membrane toxicity of the polyene antibiotics: studies on lecithin membrane models (liposomes). 1973 Antimicrob. Agents Chemother. pmid:4758835
Kasbekar DP et al. Self-induced nystatin resistance in Dictyostelium discoideum. 1985 Antimicrob. Agents Chemother. pmid:4026273
Boyce ST et al. Noncytotoxic combinations of topical antimicrobial agents for use with cultured skin substitutes. 1995 Antimicrob. Agents Chemother. pmid:7574524
Tevyashova AN et al. Structure-antifungal activity relationships of polyene antibiotics of the amphotericin B group. 2013 Antimicrob. Agents Chemother. pmid:23716057
Badaracco G and Cassani G Ribonucleic acid synthesis dependent on exogenous triphosphates in nystatin-treated cells of of Kluyveromyces latis. 1976 Antimicrob. Agents Chemother. pmid:949173
Segal E et al. Susceptibility of Prototheca species to antifungal agents. 1976 Antimicrob. Agents Chemother. pmid:984758
Groll AH et al. Compartmental pharmacokinetics and tissue distribution of multilamellar liposomal nystatin in rabbits. 2000 Antimicrob. Agents Chemother. pmid:10722496
Walker-Caprioglio HM et al. Antibodies to nystatin demonstrate polyene sterol specificity and allow immunolabeling of sterols in Saccharomyces cerevisiae. 1989 Antimicrob. Agents Chemother. pmid:2694950
Wasan KM et al. Physical characteristics and lipoprotein distribution of liposomal nystatin in human plasma. 1997 Antimicrob. Agents Chemother. pmid:9303376
Wallace TL et al. Activity of liposomal nystatin against disseminated Aspergillus fumigatus infection in neutropenic mice. 1997 Antimicrob. Agents Chemother. pmid:9333054
Brass C et al. Variability of agar dilution-replicator method of yeast susceptibility testing. 1979 Antimicrob. Agents Chemother. pmid:573098
Sletta H et al. Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin. 2005 Antimicrob. Agents Chemother. pmid:16251298
Groll AH et al. Comparative drug disposition, urinary pharmacokinetics, and renal effects of multilamellar liposomal nystatin and amphotericin B deoxycholate in rabbits. 2003 Antimicrob. Agents Chemother. pmid:14638502