chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Li XM et al. | Major proteins related to chlortetracycline biosynthesis in a Streptomyces aureofaciens production strain studied by quantitative proteomics. | 2001 | Appl. Microbiol. Biotechnol. | pmid:11778884 |
Hertweck M et al. | Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. | 2002 | Eur. J. Biochem. | pmid:11784311 |
Nettis E et al. | Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients. | 2001 | Immunopharmacol Immunotoxicol | pmid:11792017 |
Zel'tser IZ et al. | [Experimental data on hygienic norms for antibiotics of the tetracycline group]. | 1975 | Antibiotiki | pmid:1180532 |
Grega B et al. | [Effect of tetracycline antibiotics on the metabolsim of nitrogenous substances of the macroorganism. VII. Effect of megadoses of chlortetracycline on urinary excretion of some low-molecular protein metabolites in rats (author's transl)]. | 1975 | Bratisl Lek Listy | pmid:1182573 |
Zweiman GF et al. | Selective uptake of 99mTc complexes and 67Ga in acutely infarcted myocardium. | 1975 | J. Nucl. Med. | pmid:1185276 |
Suzuki K et al. | Capacitation status and in vitro fertility of boar spermatozoa: effects of seminal plasma, cumulus-oocyte-complexes-conditioned medium and hyaluronan. | 2002 | Int. J. Androl. | pmid:11903657 |
Sparkes AH et al. | The clinical efficacy of topical and systemic therapy for the treatment of feline ocular chlamydiosis. | 1999 | J. Feline Med. Surg. | pmid:11919013 |
Rae DO et al. | Effect of chlortetracycline in a trace mineral salt mix on fertility traits in beef cattle females in Florida. | 2002 | J. Anim. Sci. | pmid:12002324 |
Papaioannou DS et al. | A field study on the effect of in-feed inclusion of a natural zeolite (clinoptilolite) on health status and performance of sows/gilts and their litters. | 2002 | Res. Vet. Sci. | pmid:12002638 |