chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Liu F et al. | Changes in functional diversity of soil microbial community with addition of antibiotics sulfamethoxazole and chlortetracycline. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22205443 |
Shelver WL and Varel VH | Development of a UHPLC-MS/MS method for the measurement of chlortetracycline degradation in swine manure. | 2012 | Anal Bioanal Chem | pmid:22207281 |
Dreher TM et al. | Effects of chlortetracycline amended feed on anaerobic sequencing batch reactor performance of swine manure digestion. | 2012 | Bioresour. Technol. | pmid:23023238 |
Wang P et al. | Heterologous expression and manipulation of three tetracycline biosynthetic pathways. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:23024027 |
Stone JJ et al. | Impact of chlortetracycline on sequencing batch reactor performance for swine manure treatment. | 2011 | Bioresour. Technol. | pmid:21724384 |
Wu RB et al. | Prevalence and diversity of class 1 integrons and resistance genes in antimicrobial-resistant Escherichia coli originating from beef cattle administered subtherapeutic antimicrobials. | 2011 | J. Appl. Microbiol. | pmid:21645183 |
Volkers G et al. | Recognition of drug degradation products by target proteins: isotetracycline binding to Tet repressor. | 2011 | J. Med. Chem. | pmid:21699184 |
Bernabò N et al. | The role of actin in capacitation-related signaling: an in silico and in vitro study. | 2011 | BMC Syst Biol | pmid:21450097 |
Miah AG et al. | Intracellular signaling cascades induced by relaxin in the stimulation of capacitation and acrosome reaction in fresh and frozen-thawed bovine spermatozoa. | 2011 | Anim. Reprod. Sci. | pmid:21493019 |
Miyata M et al. | Electrochemical oxidation of tetracycline antibiotics using a Ti/IrO2 anode for wastewater treatment of animal husbandry. | 2011 | Water Sci. Technol. | pmid:21278467 |
Ni Y et al. | Spectrophotometric study of the interaction between chlorotetracycline and bovine serum albumin using Eosin Y as site marker with the aid of chemometrics. | 2011 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:21163687 |
Motoyama M et al. | Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level. | 2011 | Chemosphere | pmid:21570103 |
Kwon JW | Fate of chlortetracycline in Korean arable soil. | 2011 | Bull Environ Contam Toxicol | pmid:21553029 |
Kwon JW | Mobility of veterinary drugs in soil with application of manure compost. | 2011 | Bull Environ Contam Toxicol | pmid:21553030 |
Mirshokraei P et al. | Pentoxifylline induces capacitation and acrosome reaction and improves quality of motility in canine ejaculated spermatozoa. | 2011 | Res. Vet. Sci. | pmid:21324497 |
Allen HK et al. | Antibiotics in feed induce prophages in swine fecal microbiomes. | 2011 | MBio | pmid:22128350 |
Le T et al. | Rapid and sensitive enzyme-linked immunosorbent assay and immunochromatographic assay for the detection of chlortetracycline residues in edible animal tissues. | 2011 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21793687 |
Chen CS et al. | Effects of engineered nanoparticles on the assembly of exopolymeric substances from phytoplankton. | 2011 | PLoS ONE | pmid:21811550 |
Stanton TB et al. | Chlortetracycline-resistant intestinal bacteria in organically raised and feral Swine. | 2011 | Appl. Environ. Microbiol. | pmid:21821750 |
Bergqvist AS et al. | Single layer centrifugation of stallion spermatozoa through Androcollâ„¢-E does not adversely affect their capacitation-like status, as measured by CTC staining. | 2011 | Reprod. Domest. Anim. | pmid:20546180 |