chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Chi Z et al. | Binding of tetracycline and chlortetracycline to the enzyme trypsin: spectroscopic and molecular modeling investigations. | 2011 | PLoS ONE | pmid:22205948 |
Nelson ML and Levy SB | The history of the tetracyclines. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191524 |
Duggar BM | Aureomycin: a product of the continuing search for new antibiotics. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191532 |
Zhang D et al. | Strong adsorption of chlorotetracycline on magnetite nanoparticles. | 2011 | J. Hazard. Mater. | pmid:21724321 |
Stone JJ et al. | Impact of chlortetracycline on sequencing batch reactor performance for swine manure treatment. | 2011 | Bioresour. Technol. | pmid:21724384 |
Guillot M et al. | In growing pigs, chlortetracycline induces a reversible green bone discoloration and a persistent increase of bone mineral density dependent of dosing regimen. | 2011 | Res. Vet. Sci. | pmid:20723952 |
Kato Y et al. | Capacitation status of activated bovine sperm cultured in media containing methyl-β-cyclodextrin affects the acrosome reaction and fertility. | 2011 | Zygote | pmid:20727245 |
Wu RB et al. | Prevalence and diversity of class 1 integrons and resistance genes in antimicrobial-resistant Escherichia coli originating from beef cattle administered subtherapeutic antimicrobials. | 2011 | J. Appl. Microbiol. | pmid:21645183 |
Volkers G et al. | Recognition of drug degradation products by target proteins: isotetracycline binding to Tet repressor. | 2011 | J. Med. Chem. | pmid:21699184 |
Alexander TW et al. | Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. | 2011 | BMC Microbiol. | pmid:21261985 |
Chander Y et al. | Identification of the tet(B) resistance gene in Streptococcus suis. | 2011 | Vet. J. | pmid:20696603 |
Griffin MO et al. | Tetracycline compounds with non-antimicrobial organ protective properties: possible mechanisms of action. | 2011 | Pharmacol. Res. | pmid:20951211 |
Stone JJ et al. | Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. | 2011 | J Environ Sci Health B | pmid:21877979 |
Wan Y et al. | [Effect of soil organic matter and cadmium (II) on adsorption and desorption of chlortetracycline in soil]. | 2010 | Huan Jing Ke Xue | pmid:21360898 |
Alexander TW et al. | Farm-to-fork characterization of Escherichia coli associated with feedlot cattle with a known history of antimicrobial use. | 2010 | Int. J. Food Microbiol. | pmid:19963297 |
Reinbold JB et al. | Plasma pharmacokinetics of oral chlortetracycline in group fed, ruminating, Holstein steers in a feedlot setting. | 2010 | J. Vet. Pharmacol. Ther. | pmid:20444029 |
Giannetti L et al. | Tetracycline residues in royal jelly and honey by liquid chromatography tandem mass spectrometry: validation study according to Commission Decision 2002/657/EC. | 2010 | Anal Bioanal Chem | pmid:20607522 |
Ji K et al. | Effects of sulfathiazole, oxytetracycline and chlortetracycline on steroidogenesis in the human adrenocarcinoma (H295R) cell line and freshwater fish Oryzias latipes. | 2010 | J. Hazard. Mater. | pmid:20630653 |
Breininger E et al. | Capacitation inducers act through diverse intracellular mechanisms in cryopreserved bovine sperm. | 2010 | Theriogenology | pmid:20580081 |
Brosche S and Backhaus T | Toxicity of five protein synthesis inhibiting antibiotics and their mixture to limnic bacterial communities. | 2010 | Aquat. Toxicol. | pmid:20655118 |