chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Lakhotia RL and Stephens JF | Drug resistance and R factors among enterobacteria isolated from eggs. | 1973 | Poult. Sci. | pmid:4128258 |
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Laird RD and Drill VA | Lipotropic activity of inositol and chlortetracycline alone and in various combinations of choline, vitamin B 12 and folic acid. Activity of three liver extracts with assays for these substances. | 1971 | Arch Int Pharmacodyn Ther | pmid:4107960 |
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Sisken JE et al. | Studies on the role of Ca++ in cell division with the use of fluorescent probes and quantitative video intensification microscopy. | 1985 | Prog. Clin. Biol. Res. | pmid:4080730 |
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Miller BL and Wyatt RD | Effect of dietary aflatoxin on the uptake and elimination of chlortetracycline in broiler chicks. | 1985 | Poult. Sci. | pmid:4048055 |
Waugh MA and Nayyar KC | Triple tetracycline (Deteclo) in the treatment of chlamydial infection of the female genital tract. | 1977 | Br J Vener Dis | pmid:403996 |
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Martin SW | A mail survey of the efficacy of prophylactic medication in feed and/or water of feedlot calves. | 1985 | Can. J. Comp. Med. | pmid:3986676 |
Chait DH and Katz DA | Myospherulosis. | 1985 | Nebr Med J | pmid:3982551 |
Wyatt RD and Miller BL | Effect of mixed organic acid administration on blood levels of chlortetracycline in broiler chicks. | 1985 | Poult. Sci. | pmid:3975199 |
Lüthgen W et al. | [Psittacosis therapy and prophylaxis in lovebirds, cockatiels and other problem birds]. | 1979 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:394949 |
Kim YV et al. | Chlortetracycline-mediated continuous Ca2+ oscillations in mitochondria of digitonin-treated Tetrahymena pyriformis. | 1985 | Eur. J. Biochem. | pmid:3935438 |
Dunham PB et al. | From Beaumont to poison ivy: marine sponge cell aggregation and the secretory basis of inflammation. | 1985 | Fed. Proc. | pmid:3932096 |
Northover AM | The release of membrane-associated calcium from rabbit neutrophils by fixatives. Implications for the use of antimonate staining to localize calcium. | 1985 | Histochem. J. | pmid:3930431 |
Beatson JM et al. | A clinical comparison of pivmecillinam plus pivampicillin (Miraxid) and a triple tetracycline combination (Deteclo) in respiratory infections treated in general practice. | 1985 | J. Int. Med. Res. | pmid:3930309 |
Brace LD et al. | Thromboxane A2/prostaglandin H2 mobilizes calcium in human blood platelets. | 1985 | Am. J. Physiol. | pmid:3925795 |
Henricsson V and Axéll T | Treatment of recurrent aphthous ulcers with Aureomycin mouth rinse or Zendium dentifrice. | 1985 | Acta Odontol. Scand. | pmid:3925707 |
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Awahmukalah DS and Brooks MA | Search for a sensitive stage for aposymbiosis induction in Culex pipiens pipiens by antibiotic treatment of immature stages. | 1985 | J. Invertebr. Pathol. | pmid:3918120 |
Kolesnick RN and Gershengorn MC | Arachidonic acid inhibits thyrotropin-releasing hormone-induced elevation of cytoplasmic free calcium in GH3 pituitary cells. | 1985 | J. Biol. Chem. | pmid:3918031 |
Sehlin J and Täljedal IB | 45Ca2+ uptake by dispersed pancreatic islet cells: effect of D-glucose and the calcium probe, chlorotetracycline. | 1979 | Pflugers Arch. | pmid:390493 |
Jukes TH | Some historical notes on chlortetracycline. | 1985 Sep-Oct | Rev. Infect. Dis. | pmid:3903946 |
Imam GM and Küntzel H | Mechanism of action of monoketo-organomycin, cystaurimycin and their performic acid-oxidized modifications. I. Effects on bacterial growth and ribosomal peptidyl transferase activity. | 1979 | J. Antibiot. | pmid:389914 |
Higashihara M and Kume S | [Calcium-platelet endogenous protein phosphorylation, Quin 2 fluorescence, CTC fluorescence]. | 1985 | Rinsho Byori | pmid:3897654 |
Lee MA and Storey BT | Evidence for plasma membrane impermeability to small ions in acrosome-intact mouse spermatozoa bound to mouse zonae pellucidae, using an aminoacridine fluorescent pH probe: time course of the zona-induced acrosome reaction monitored by both chlortetracycline and pH probe fluorescence. | 1985 | Biol. Reprod. | pmid:3840700 |
Coates TD et al. | Localization of chlorotetracycline fluorescence in human polymorphonuclear neutrophils. | 1987 | Blood | pmid:3828534 |
Zinn RA | Short-term effect of antibiotic feeding on site and extent of digestion of growing and finishing diets in feedlot cattle. | 1986 | J. Anim. Sci. | pmid:3818474 |
Babcock DF et al. | Evidence for mitochondrial localization of the hormone-responsive pool of Ca2+ in isolated hepatocytes. | 1979 | J. Biol. Chem. | pmid:381300 |
Blazhene AIu et al. | [A method of diagnosing allergy to penicillin]. | 1986 | Sov Med | pmid:3810275 |
Møller IM et al. | Chlortetracycline and the transmembrane potential of the inner membrane of plant mitochondria. | 1986 | Biochem. J. | pmid:3800917 |
SamoÄlov MO et al. | [Effect of kainic acid on the metabolism of intracellular calcium and oxidation-reduction processes in structures of the cerebral cortex]. | 1986 | Fiziol Zh SSSR Im I M Sechenova | pmid:3758403 |
Burch DG et al. | The synergistic activity of tiamulin and chlortetracycline: in-feed treatment of bacterially complicated enzootic pneumonia in fattening pigs. | 1986 | Vet. Rec. | pmid:3750792 |
Klypina NS and Plakunov VK | [Role of metabolic energy in the regulation of chlortetracycline transport in Escherichia coli]. | 1979 Mar-Apr | Mikrobiologiia | pmid:375040 |
Dennis JD | Prescription milk powders. | 1986 | Vet. Rec. | pmid:3739189 |
Täljedal IB | Polarization of chlorotetracycline fluorescence in pancreatic islet cells and its response to calcium ions and D-glucose. | 1979 | Biochem. J. | pmid:373751 |
Sasakawa S et al. | Effects of storage and 37 degrees C-incubation with fresh plasma on platelet calcium distribution, mobilization, influx and aggregability. | 1986 | Thromb. Res. | pmid:3715817 |
Brazhnikova NA et al. | [Effect of immunosorption on the functional state of immunocompetent cells]. | 1986 | Ter. Arkh. | pmid:3715755 |
Molitoris E et al. | Effects of dietary chlortetracycline on the antimicrobial resistance of broiler faecal Streptococcaceae. | 1986 | J. Appl. Bacteriol. | pmid:3710942 |
Dey BP et al. | Influence of chlortetracycline feeding on salmonellosis in calves. I. Rate and duration of shedding. II. Severity of illness. | 1978 | Int J Zoonoses | pmid:370044 |
Molitoris E et al. | Effects of dietary chlortetracycline on the antimicrobial resistance of porcine faecal streptococcaceae. | 1986 | J. Appl. Bacteriol. | pmid:3700277 |
Sokolove PM | Na+-independent, pyridine nucleotide-linked efflux of Ca2+ from preloaded rat heart mitochondria: induction by chlortetracycline. | 1987 | Biochem. Pharmacol. | pmid:3689435 |
McKellar QA et al. | Penicillin therapy of spontaneous streptococcal meningitis in pigs. | 1987 | Vet. Rec. | pmid:3686793 |
Cacciapuoti A et al. | In vitro and in vivo characterization of novel 8-methoxy derivatives of chlortetracycline. | 1987 | J. Antibiot. | pmid:3680008 |
Smith EB et al. | Direct selection of a specifically blocked mutant of Actinomadura brunnea. Isolation of a third 8-methoxy substituted chlortetracycline. | 1987 | J. Antibiot. | pmid:3680007 |
Patel M et al. | A new tetracycline antibiotic from a Dactylosporangium species. Fermentation, isolation and structure elucidation. | 1987 | J. Antibiot. | pmid:3680006 |
Patel M et al. | A novel tetracycline from Actinomadura brunnea. Fermentation, isolation and structure elucidation. | 1987 | J. Antibiot. | pmid:3680005 |
Ohga Y et al. | Multidimensional stopped-flow photometry monitoring initial processes of platelet activation. | 1987 | J. Biochem. | pmid:3667556 |
Williams RD et al. | Effect of feeding chlortetracycline on the reservoir of Salmonella typhimurium in experimentally infected swine. | 1978 | Antimicrob. Agents Chemother. | pmid:365087 |
Brady MS and Katz SE | Simplified plate diffusion system for microbial assays of antibiotics. | 1987 Jul-Aug | J Assoc Off Anal Chem | pmid:3624167 |
Shivaji S | Interaction of seminalplasmin with chlortetracycline, a fluorescent chelate probe of Ca2+. | 1987 | FEBS Lett. | pmid:3595865 |
Habara Y and Kanno T | Calcium-chlorotetracycline fluorescence and pancreatic exocrine secretion in the rat. | 1986 | Pancreas | pmid:3575299 |
Frieser J et al. | [Excretion of chlortetracycline in rainbow trout]. | 1986 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:3542481 |
Kuhrová V et al. | Ability of chloramphenicol to suppress phenotypically some bacterial mutations. | 1978 | Mol. Gen. Genet. | pmid:353493 |
Fagerberg DJ et al. | Effect of low level chlortetracycline feeding on subsequent therapy of Escherichia coli infection in chickens. | 1978 | J. Anim. Sci. | pmid:353017 |
Langlois BE et al. | Influence of chlortetracycline in swine feed on reproductive performance and on incidence and persistence of antibiotic resistant enteric bacteria. | 1978 | J. Anim. Sci. | pmid:353016 |
Perry TW et al. | Use of chlortetracycline for treatment of new feedlot cattle. | 1986 | J. Anim. Sci. | pmid:3522519 |
Sehgal VN and Prasad AL | Donovanosis. Current concepts. | 1986 Jan-Feb | Int. J. Dermatol. | pmid:3512463 |
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Weissmann G et al. | Synergy between phorbol esters, 1-oleyl-2-acetylglycerol, urushiol, and calcium ionophore in eliciting aggregation of marine sponge cells. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3458250 |
Phelps PV et al. | Effect of prefeeding on physiological parameters associated with turkey poult mortality. | 1987 | Poult. Sci. | pmid:3447147 |
De Piceis Polver P et al. | Histochemical demonstration of oxidoreductase activities in the fat body and symbionts of Blattella germanica (Blattodea) following chlortetracycline-treatment. | 1987 | Basic Appl Histochem | pmid:3442552 |
Brophy PO et al. | Sensitivity patterns of Escherichia coli isolated from calves during and following prophylactic chlortetracycline therapy. | 1977 Jul-Aug | Br. Vet. J. | pmid:343877 |
Fenwick BW and Olander HJ | Experimental infection of weanling pigs with Salmonella typhisuis: effect of feeding low concentrations of chlortetracycline, penicillin, and sulfamethazine. | 1987 | Am. J. Vet. Res. | pmid:3434900 |
Dey BP et al. | Therapeutic responses of piglets to experimentally induced colibacillosis. | 1977 | Res. Vet. Sci. | pmid:343209 |
Quarles CL et al. | Effect of low level feeding chlortetracycline on subsequent therapy of chicks infected with Salmonella typhimurium. | 1977 | Poult. Sci. | pmid:343088 |
DeFeo TT et al. | Ca2+ signals obtained with multiple indicators in mammalian vascular muscle cells. | 1987 | Am. J. Physiol. | pmid:3425745 |
pmid:3417597 | ||||
Kashani AB and Carlson CW | Use of sunflower seeds in grower diets for pullets and subsequent performance as affected by aureomycin and pelleting. | 1988 | Poult. Sci. | pmid:3405923 |
Raineri M and Modenesi P | Membrane-bound Ca2+ distribution visualized by chlorotetracycline fluorescence during morphogenesis of soredia in a lichen. | 1988 | Histochem. J. | pmid:3391800 |
Klypina NS and Plakunov VK | [Patterns in chlortetracycline absorption and the regulation of that process in Escherichia coli K-12]. | 1977 | Nauchnye Doki Vyss Shkoly Biol Nauki | pmid:338038 |
Korsrud GO and MacNeil JD | A comparison of three bioassay techniques and high performance liquid chromatography for the detection of chlortetracycline residues in swine tissues. | 1988 Apr-Jun | Food Addit Contam | pmid:3360203 |