chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Morrison AI | Treatment of relapses and re-infections in non-specific urethritis. | 1967 | Br J Vener Dis | pmid:4963698 |
Helmy N and Fowler W | Intensive and prolonged tetracycline therapy in non-specific urethritis. | 1975 | Br J Vener Dis | pmid:811319 |
Willcox RR | 'Triple tetracycline' in the treatment of non-gonococcal urethritis in males. | 1972 | Br J Vener Dis | pmid:4624388 |
THOMSON GM | Treatment of male gonorrhoea with a chlortetracycline-sulphonamide combination. | 1959 | Br J Vener Dis | pmid:13838153 |
WILLCOX RR | Comparison of oxytetracycline and chlortetracycline in the treatment of non-gonococcal urethritis. | 1955 | Br J Vener Dis | pmid:14389704 |
Waugh MA and Nayyar KC | Triple tetracycline (Deteclo) in the treatment of chlamydial infection of the female genital tract. | 1977 | Br J Vener Dis | pmid:403996 |
CAMERON JM | Keratodermia blennorrhagica. | 1956 | Br J Vener Dis | pmid:13316049 |
Andrew GS et al. | Clinical trial of clomocycline (Megaclor) in gonococcal and non-gonococcal urethritis. | 1969 | Br J Vener Dis | pmid:4892122 |
Bhattacharyya MN and Morton RS | Long-term triple tetracycline ("Deteclo") treatment of non-specific urethritis. | 1973 | Br J Vener Dis | pmid:4202724 |
Thambar IV et al. | Double-blind comparison of two regimens in the treatment of nongonococcal urethritis. Seven-day vs 21-day course of triple tetracyclinc (Deteclo). | 1979 | Br J Vener Dis | pmid:114198 |
A TRIAL of penicillin and chlortetracycline in treatment of bronchitis; report from the city general hospital, Sheffield. | 1958 | Br Med J | pmid:13499917 | |
LOWBURY EJ and CASON JS | Aureomycin and erythromycin therapy for str. pyogenes in burns. | 1954 | Br Med J | pmid:13199343 |
BAILEY CA and JUMEAUX CV | Aureomycin in treatment of peritonitis. | 1950 | Br Med J | pmid:15405002 |
SELIGMAN SA | Treatment of actinomycosis with aureomycin. | 1954 | Br Med J | pmid:13160490 |
WILLCOX RR | Aureomycin; a new treatment for syphilis? | 1949 | Br Med J | pmid:15395481 |
JACKSON DM | Suppurative thrombophlebitis treated with aureomycin. | 1951 | Br Med J | pmid:14801514 |
Howie JW | Letter: Chronic brucellosis. | 1974 | Br Med J | pmid:4817169 |
SEAL SC et al. | Further trial of aureomycin in the treatment of cholera. | 1954 | Br Med J | pmid:13140854 |
JOPLING WH and SCHOFIELD FD | Failure of antibiotics in a case of staphylococcal bacteriaemia. | 1953 | Br Med J | pmid:13106354 |
FORBES GB | Sensitivity studies on Shigella sonnei. | 1953 | Br Med J | pmid:13042164 |
LINDECK EW | Aureomycin in brucellosis. | 1950 | Br Med J | pmid:15414336 |
SOLOMONS B | Aureomycin: its topical use in some skin diseases; a clinical study. | 1951 | Br Med J | pmid:14869633 |
AINSLIE D | The treatment of blepharitis. | 1951 | Br Med J | pmid:14869654 |
KELLY HH | Intestinal actinomycosis treated with chloramphenicol and aureomycin. | 1951 | Br Med J | pmid:14869720 |
EGERTON ME | Two cases of tetanus neonatorum treated with penicillin and aureomycin. | 1952 | Br Med J | pmid:14896195 |
FERGUSSON AG and ROBERTS GB | A case of granuloma inguinale in Scotland; response to aureomycin. | 1953 | Br Med J | pmid:13042209 |
TOMASZEWSKI T | Side-effects of chloramphenicol and aureomycin, with special reference to oral lesions. | 1951 | Br Med J | pmid:14821422 |
TREATMENT of clinical pneumonia with antibiotics; report by a Subcommittee of the Antibiotics Clinical Trials (Nontuberculous) Committee of the Medical Research Council. | 1951 | Br Med J | pmid:14879098 | |
WILLCOX RR | Aureomycin and chloramphenicol in chancroid. | 1951 | Br Med J | pmid:14821463 |
EADIE MB et al. | Aureomycin in the treatment of pneumonia. | 1951 | Br Med J | pmid:14879099 |
MARSON FG et al. | Pylephlebitis and septicaemia treated with aureomycin. | 1953 | Br Med J | pmid:13032490 |
LIVER injury by antibiotics. | 1953 | Br Med J | pmid:13032497 | |
SHANKS RA | Aureomycin and chloramphenicol in infantile diarrhoea. | 1951 | Br Med J | pmid:14848571 |
GALPINE JF | A case of abortus infection treated with aureomycin. | 1949 | Br Med J | pmid:18228883 |
Chloramphenicol and tetracyclines. | 1968 | Br Med J | pmid:4968330 | |
CHAPPELL AG | CHLORMETHYLENCYCLINE. | 1965 | Br Med J | pmid:14257416 |
Backhouse CI and Cartwright RY | An outbreak of streptococcal skin sepsis in a closed community. | 1974 | Br Med J | pmid:4606217 |
Rees E and Hobson D | Sticky eye in the newborn. | 1974 | Br Med J | pmid:4216387 |
SORSBY A et al. | Aureomycin, chloramphenicol, and terramycin in ophthalmology. | 1953 | Br Med J | pmid:13059478 |
MARSDEN JP and COUGHLAN WJ | A case of confluent chicken-pox with haemorrhagic symptoms. | 1952 | Br Med J | pmid:14925367 |
FINLAND M and GARROD LP | Demethylchlortetracycline. | 1960 | Br Med J | pmid:13822921 |
NELIGAN GA and ELDERKIN FM | TREATMENT OF ACUTE HAEMATOGENOUS OSTEITIS IN CHILDREN ASSESSED IN A CONSECUTIVE SERIES OF SELECTED CASES. | 1965 | Br Med J | pmid:14278840 |
BETTLEY FR and FAIRBURN EA | Treatment of some bullous eruptions with aureomycin and chloramphenicol. | 1951 | Br Med J | pmid:14858848 |
Howells CH et al. | Changing incidence of trachoma in the West Midlands. | 1969 | Br Med J | pmid:5823063 |
MAGNUSSON JH et al. | Aureomycin treatment of infantile diarrhoea and vomiting. | 1950 | Br Med J | pmid:15426761 |
GARROD LP | Chemotherapy. IV. The newer antibiotics. | 1950 | Br Med J | pmid:14772464 |
CARTER AB | Investigation into the effects of aureomycin and chloramphenicol in herpes zoster. | 1951 | Br Med J | pmid:14830825 |
PHILLIPS B | Failure of aureomycin in dermatitis herpetiformis. | 1951 | Br Med J | pmid:14830884 |
COMPARISON of tetracycline with chlortetracycline in treatment of pneumonia; report from the City General Hospital, Sheffield. | 1956 | Br Med J | pmid:13364403 | |
Management of common skin infections. | 1968 | Br Med J | pmid:4234090 | |
DRURY MI | A case of Friedländer's pneumonia treated with aureomycin. | 1953 | Br Med J | pmid:13106381 |
ELEK SD et al. | Laboratory aspects of combined antibiotic treatment. | 1953 | Br Med J | pmid:13106416 |
WILLCOX RR and FINDLAY GM | Urethritis, gonococcal and nonspecific, treated by aureomycin. | 1949 | Br Med J | pmid:18147222 |
CRUICKSHANK JC | Failure of aureomycin in experimental melioidosis. | 1949 | Br Med J | pmid:18147831 |
ADAMS AR | Treatment of bowel infections of the tropics. | 1953 | Br Med J | pmid:13009184 |
BEDFORD PD | Idiosyncrasy to aureomycin. | 1951 | Br Med J | pmid:14839287 |
FERGUSSON AG | Pemphigus vegetans; response to aureomycin therapy. | 1952 Jul-Aug | Br. J. Dermatol. | pmid:14954101 |
McCONACHIE JA and ANDERSON TE | Aureomycin in the treatment of Kaposi's varicelliform eruption. | 1951 Aug-Sep | Br. J. Dermatol. | pmid:14869601 |
SMITH MA et al. | A controlled trial of oral antibiotics in the treatment of acne vulgaris. | 1962 | Br. J. Dermatol. | pmid:13914345 |
Ward JM et al. | A double-blind trial of clomocycline in the treatment of persistent palmoplantar pustulosis. | 1976 | Br. J. Dermatol. | pmid:788767 |
Savin JA | International mortality from bullous diseases since 1950. | 1976 | Br. J. Dermatol. | pmid:766815 |
SOMMERVILLE J et al. | Kaposi's varicelliform eruption: record of an outbreak. | 1951 | Br. J. Dermatol. | pmid:14839213 |
LANG JM et al. | The effect of giving stilboestrol and chloretetracycline to colostrumfed calves. | 1959 | Br. J. Nutr. | pmid:14413862 |
TAYLOR JH and ROWELL JG | The effect of various levels of penicillin and chlortetracycline in the diet of fattening pigs. | 1957 | Br. J. Nutr. | pmid:13426450 |
DHOPESHWARKAR GA et al. | The effect of vegetarianism and antibiotics upon proteins and vitamin B12 in the blood. | 1956 | Br. J. Nutr. | pmid:13315929 |
ROY JH et al. | THE NUTRITION OF THE VEAL CALF; THE EFFECT OF ANAEMIA AND OF IRON AND CHLORTETRACYCLINE SUPPLEMENTATION ON THE PERFORMANCE OF CALVES GIVEN LARGE QUANTITIES OF WHOLE MILK. | 1964 | Br. J. Nutr. | pmid:14243804 |
ROINE P et al. | The mode of action of aureomycin in the guinea-pig. | 1955 | Br. J. Nutr. | pmid:14389636 |
ROY JH et al. | The nutritive value of colostrum for the calf. 11. The effect of aureomycin on the performance of colostrum-deprived calves. | 1955 | Br. J. Nutr. | pmid:14351664 |
BARBER RS et al. | Antibiotic and copper supplements for fattening pigs. | 1955 | Br. J. Nutr. | pmid:13284220 |
BRAUDE R et al. | The effect of aureomycin on the gut of the pig. | 1955 | Br. J. Nutr. | pmid:13284217 |
DICKINSON CD and SCOTT PP | Effects of adding penicillin and aureomycin to the diet of cats. | 1954 | Br. J. Nutr. | pmid:13208958 |
MANN SO et al. | Effect of feeding aureomycin to calves upon the establishment of their normal rumen microflora and microfauna. | 1954 | Br. J. Nutr. | pmid:13190133 |
BARBER RS et al. | Antibiotics in the diet of the fattening pig. | 1953 | Br. J. Nutr. | pmid:13106237 |
Freeman BM et al. | Dietary aureomycin and the response of the fowl to stressors. | 1975 | Br. Poult. Sci. | pmid:168946 |
Dong XF et al. | Effects of dietary polysavone (Alfalfa extract) and chlortetracycline supplementation on antioxidation and meat quality in broiler chickens. | 2011 | Br. Poult. Sci. | pmid:21732875 |
Shi BL et al. | Effects of chitosan on growth performance and energy and protein utilisation in broiler chickens. | 2005 | Br. Poult. Sci. | pmid:16268112 |
Saloma AE et al. | The intermittent feeding of anti-bacterial and-or antifungal agents to laying hens. | 1970 | Br. Poult. Sci. | pmid:5433120 |
King JO | The continuous feeding of two antibiotics to growing rabbits. | 1967 | Br. Vet. J. | pmid:6074284 |
Brophy PO et al. | Sensitivity patterns of Escherichia coli isolated from calves during and following prophylactic chlortetracycline therapy. | 1977 Jul-Aug | Br. Vet. J. | pmid:343877 |
Ajayi JA and Todd AC | Relationships between two levels of aureomycin-sulphamethazine supplementation and acquisition of resistance to ovine coccidiosis. | 1977 Mar-Apr | Br. Vet. J. | pmid:608056 |
Sojka WJ et al. | A survey of drug resistance in Salmonella isolated from animals in England and Wales during 1971. | 1974 Mar-Apr | Br. Vet. J. | pmid:4601304 |
GOMES GL | [Aureomycin therapy of leishmaniasis; preliminary note]. | 1955 May 7-28 | Bras Med | pmid:13239913 |
de MAGALHAES O et al. | [Attempts at therapy of neotropic exanthematous typhus in Brazil terramycin and aureomycin); preliminary note]. | 1950 Dec 16-30 | Bras Med | pmid:14839187 |
MICHALICKOVA J et al. | [Coli bacteria infections and toxic dyspepsia in children treated with aureomycin]. | 1951 | Bratisl Lek Listy | pmid:14869557 |
Grega B et al. | [Effect of tetracycline antibiotics on the metabolsim of nitrogenous substances of the macroorganism. VII. Effect of megadoses of chlortetracycline on urinary excretion of some low-molecular protein metabolites in rats (author's transl)]. | 1975 | Bratisl Lek Listy | pmid:1182573 |
Barna K et al. | [Free amino acids in blood serum of the rats after a single of chlortetracycline (author's transl)]. | 1975 | Bratisl Lek Listy | pmid:1156903 |
SOBEK V | [On the problem of the protective effect of chlortetracycline against intoxication by bacterial toxins]. | 1963 | Bratisl Lek Listy | pmid:13989761 |
Surzin J et al. | [Effect of tetracycline antibiotics on the metabolism of nitrogenous substances in macroorganisms. I. Changes in ninhydrine-positive compounds in the liver of the rat following single administration of chlortetracycline]. | 1973 | Bratisl Lek Listy | pmid:4751880 |
DE MAERTELAERE R | [Not Available]. | 1956 | Brux Med | pmid:13374401 |
VANDERHOEFT PJ et al. | [Differential growth of the right and left homologous bone under the effect of a right arteriovenous fistula. Quantitative study with the aid of tetracycline]. | 1963 | Bull Acad R Med Belg | pmid:13996212 |
Kwon JW | Fate of chlortetracycline in Korean arable soil. | 2011 | Bull Environ Contam Toxicol | pmid:21553029 |
Kwon JW | Mobility of veterinary drugs in soil with application of manure compost. | 2011 | Bull Environ Contam Toxicol | pmid:21553030 |
Kim HY et al. | Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells. | 2012 | Bull Environ Contam Toxicol | pmid:22673765 |
Magdaleno A et al. | Toxicity and Genotoxicity of Three Antimicrobials Commonly Used in Veterinary Medicine. | 2017 | Bull Environ Contam Toxicol | pmid:28434066 |
Elmund GK et al. | Role of excreted chlortetracycline in modifying the decomposition process in feedlot waste. | 1971 Mar-Apr | Bull Environ Contam Toxicol | pmid:5153752 |
Katz SE and Fassbender CA | Improved sample preparation procedure for determining chlortetracycline in chicken tissue and related organs. | 1971 Jan-Feb | Bull Environ Contam Toxicol | pmid:4949285 |
Mugera GM et al. | Treatment of East Coast fever with aureomycin. | 1973 | Bull Epizoot Dis Afr | pmid:4802644 |
LEPAGE F et al. | [Aureomycin in the treatment of puerperal mastitis]. | 1950 | Bull Fed Soc Gynecol Obstet Lang Fr | pmid:14812205 |
VAYSSIERE E and SERMENT H | [Grave accident during aureomycin therapy of abscess of the breast]. | 1951 | Bull Fed Soc Gynecol Obstet Lang Fr | pmid:14879186 |
GAUCHERAND J et al. | [First results of treatment of acute puerperal mastitis with aureomycin]. | 1950 | Bull Fed Soc Gynecol Obstet Lang Fr | pmid:14792153 |