chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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ASNIN DI and SUTEEVA TG | [Treatment of cervico-facial actinomycosis with biomycin (chlortetracycline)]. | 1960 | Sov Med | pmid:13794830 |
BALSANO F et al. | [First observations on the use of demethylchlorotetracycline in phlogoses of the urinary tract]. | 1960 | Minerva Med. | pmid:13796322 |
BANASZAK EF et al. | Comparative effect of heparin and other agents on traumatic shock in the rat. | 1959 | Am. J. Physiol. | pmid:13796360 |
BOGER WP and GAVIN JJ | Demethylchlortetracycline: serum concentration studies and cerebrospinal fluid diffusion. | 1959-1960 | Antibiot Annu | pmid:13802119 |
BOLGERT M et al. | [Pemphigus foliaceus complicated by zona, treated by the association of quinacrine, aureomycin in large doses and corticotherapy in small doses]. | 1960 Jan-Mar | Bull Soc Fr Dermatol Syphiligr | pmid:13802295 |
BOLGERT M and LE SOURD M | [Pemphigus vegetans treated by the association of quinacrine and aureomycin since 1952 (sixth report). Recovery maintained without any treatment for a year and a half]. | 1960 Jan-Mar | Bull Soc Fr Dermatol Syphiligr | pmid:13802300 |
BYKOVA MA and AVER'IANOVA LL | [A method for the determination of chloretracycline concentrations in liquids, organs and tissues of animals with the aid of paper disks]. | 1959 Nov-Dec | Antibiotiki | pmid:13806624 |
CHAMPIGNY O et al. | [Influence of aureomycin on the ponderal growth and duration of survival of the adrenalectomized rat]. | 1960 | Arch Sci Physiol (Paris) | pmid:13809086 |
CHAVEZ MAX G | Therapeutic evaluation of demethylchlorte-tracycline in human brucellosis. | 1959-1960 | Antibiot Annu | pmid:13809530 |
CHERNUKH AM and BALASHOVA VA | [On the problem of the effect of chlortetracycline and tetracycline on iron cotent in the blood serum]. | 1959 Jul-Aug | Antibiotiki | pmid:13809691 |
CLAPPER WE and PROPER R | Comparative activity of demethyl-chlortetracycline and tetracycline against organisms commonly encountered in clinical material. | 1960 | Antibiot Chemother (Northfield) | pmid:13810415 |
COOPER MS and ALLEN GA | The effect of chlortetracycline on the immune response. II. Influence on development of protective antibodies after vaccination with a live, avirulent strain of Erysipelothrix rhusiopathiae. | 1959 | J. Immunol. | pmid:13811803 |
CRESTA M et al. | [Corn and aureomycin in the alimentation of the rat]. | 1959 | Boll. Soc. Ital. Biol. Sper. | pmid:13812812 |
DONCKASTER R and DONOSO A | [Trial therapy of chronic intestinal amebiasis with demethylchlortetracycline. Probable action of this drug on giardiasis]. | 1960 Apr-Jun | Bol Chil Parasitol | pmid:13817502 |
DOROSHOW LW and ABESHOUSE BS | Criteria for the evaluation of therapeutic agents in the treatment of urinary tract infections. I. 6-demethyl-chlortetracycline. | 1960 | Sinai Hosp J (Balt) | pmid:13817712 |
DUKE CJ et al. | Demethylchlortetracycline in the treatment of pneumonia. | 1959-1960 | Antibiot Annu | pmid:13818530 |
EGOROV NS and BARANOVA IP | [Effect of p-dimethylaminobenzaldehyde on chlortetracycline synthesis]. | 1959 Sep-Oct | Antibiotiki | pmid:13819549 |
EVERARD CO and FEDER WA | Effective increase in nematode populations by the addition of aureomycin. | 1959 | Nature | pmid:13821046 |
FEDOTOVA MI et al. | [Experimental data on the investigation of the effect of chloretetracycline for parenteral administration in various forms of complex therapy of acute radiation sickness]. | 1960 Jan-Feb | Antibiotiki | pmid:13821882 |
FENNER O | [Demethylchlortetracycline (ledermycin). Comparative bacteriological research]. | 1960 | Med Welt | pmid:13822177 |
FINLAND M and GARROD LP | Demethylchlortetracycline. | 1960 | Br Med J | pmid:13822921 |
FINLAND M et al. | Observations on demethylchlortetracycline. | 1959-1960 | Antibiot Annu | pmid:13822922 |
FRAGA FILHO C et al. | [Clinical and experimental investigations on a new compound of tetracycline: demethylchlortetracycline]. | 1960 | Hospital (Rio J) | pmid:13824296 |
FRIGERIO MJ | [A new tetracycline derivative: demethyl-chlortetracycline]. | 1960 | Dia Med | pmid:13825221 |
FUHRMAN DL and DROWNS BV | Demethylchlortetracycline. The clinical aspect of its use in dermatology. | 1960 | Arch Dermatol | pmid:13825561 |
FUJII R et al. | Clinical results with demethylchlortetracycline in pediatrics in Japan and comparative studies with other tetracyclines. | 1959-1960 | Antibiot Annu | pmid:13825576 |
GARSON W et al. | Preliminary report on the effect of dextrosulphenidol in experimental syphilis. | 1959-1960 | Antibiot Annu | pmid:13826688 |
GLAZKOVA Ts | [Comparative evaluation of the effect of biomycin and of other drugs in the treatment of patients with dysentery]. | 1959 | Tr Leningr Sanitarnogig Med Inst | pmid:13828397 |
GRANDI F and GOLFIERI G | [On a case of neonatal sepsis with multiple osteoarticular localizations treated with chlortetracycline]. | 1959 | Clin Pediatr (Bologna) | pmid:13828894 |
GROMASHEVSKAIA LL | [Nature of the effect of antibiotics on the organism in relation to its original state]. | 1960 Mar-Apr | Antibiotiki | pmid:13829524 |
GUILLAUME J and OSTEUX R | [Mode of action of aureomycin. Inhibition of the metabolism of glucose and the acids of the citric cycle in Proteus mirabilis]. | 1959 | C. R. Hebd. Seances Acad. Sci. | pmid:13830158 |
GUILLAUME J and OSTEUX R | [On the mode of action of aureomycin in Proteus mirabilis. Existence of a tricarboxylic cycle and its inhibition]. | 1959 | C. R. Seances Soc. Biol. Fil. | pmid:13830159 |
KAWABATA T et al. | Factors affecting the decomposition of oxytetracycline and chlortetracycline. | 1960 | J. Antibiot. | pmid:13830905 |
SOBEK V | [Contribution to the influence of growth by chlortetracycline]. | 1960 | Cesk Fysiol | pmid:13832358 |
SOBEK V | [Effect of chlortetracycline on Clostridium perfringens toxin intoxication]. | 1960 | Cesk Fysiol | pmid:13832359 |
SOBEK V | [On the problem of the effect of chlortetracycline on the macroorganism]. | 1960 Jan-Feb | Antibiotiki | pmid:13832361 |
STARSHOV PD | [Prevention of riboflavin-deficiency appearing during chlortetracycline therapy of patients with acute dysentery]. | 1959 Jul-Aug | Antibiotiki | pmid:13833867 |
STOKSTAD EL et al. | The effect of calcium salts on chlortetracycline absorption. | 1959-1960 | Antibiot Annu | pmid:13834851 |
SWEENEY WM et al. | Antibiotic activity in urine and feces after oral and intravenous administration of demethylchlertetracycline. | 1960 | N. Engl. J. Med. | pmid:13836078 |
THIERS H et al. | [Treatment of visceral syphilis by aureomycin applied intravenously and by corticotherapy]. | 1959 | J Med Lyon | pmid:13837820 |
THOMSON GM | Treatment of male gonorrhoea with a chlortetracycline-sulphonamide combination. | 1959 | Br J Vener Dis | pmid:13838153 |
TRAFTON HM and LIND HE | Demethylchlortetracycline: effectiveness and tolerance in urinary tract infections. | 1960 | Antibiot Chemother | pmid:13839143 |
TUNEVALL G and FRISK AR | Bacteriological and clinical evaluation of demethylchlortetracycline. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13839825 |
TUNEVALL G and FRISK AR | [Demethylchlortetracycline]. | 1960 | Nord Med | pmid:13839826 |
VAUGHN RH et al. | Antibiotics in poultry meat preservation. Development in vitro of bacterial resistance to chlortetracycline. | 1960 | Appl Microbiol | pmid:13841490 |
VAVRECKA M et al. | [Effect of chlortetracycline on fat metabolism]. | 1960 | Cesk Fysiol | pmid:13841503 |
VINEYARD JP et al. | Clinical and laboratory evaluation of demethylchlortetracycline. | 1959-1960 | Antibiot Annu | pmid:13842376 |
WORLEY DE and HANSEN MF | Chemotherapeutic studies of gastrointestinal parasites of beef cattle and bison in Kansa. | 1960 | Am. J. Vet. Res. | pmid:13845988 |
YAGI K et al. | Mechanism of inhibition of D-amino acid oxidase. I. Inhibitory action of chlortetracycline. | 1959 | Biochim. Biophys. Acta | pmid:13846343 |
ZATULOVS'KYI BH | [Comparative studies of the effect of furacillin, levomycetin and biomycin on dysenterial bacilli]. | 1960 | Mikrobiol Zh | pmid:13847084 |
HALL RH and GALE GO | Augmentation of chlortetracycline activity against two strains of Staphylococcus by kinetin. | 1960 | Proc. Soc. Exp. Biol. Med. | pmid:13848399 |
ASKAROV AA and IAKHONTOVA IuV | [Biomycin therapy of right-sided colitis]. | 1958 | Izv Seriia Fiziol Meditsiny Qazaq SSR Ghylum Akad | pmid:13848862 |
HIRSCH HA et al. | [Demethylchlortetracycline. A new and more stable antibiotic of the tetracycline group with a stronger and longer-acting antibacterial effect]. | 1959 | Munch Med Wochenschr | pmid:13852431 |
BRECHT W | [Clinical experiences with a new tetracycline preparation]. | 1960 | Med Welt | pmid:13855582 |
BAETGEN D | [Therapeutic successes with supramycin in pediatric hospitals]. | 1962 | Med Monatsschr | pmid:13863885 |
BALSANO F et al. | The effect of demethylchlorotetracycline on dietetic necrosis of the liver in the rat. | 1962 | Panminerva Med | pmid:13864513 |
BERCHEV K and POPOV E | [On patho-anatomical changes during biomycin therapy. (Contribution to a case of intravenous biomycin therapy)]. | 1961 | Suvr Med (Sofiia) | pmid:13867462 |
BERK JE and KANTOR SM | The identification of gastric cancer by means of fluorescence of gastric sediment induced by declomycin. | 1961 | Bull Sinai Hosp Detroit | pmid:13867864 |
BERNHEIM M and LARBRE F | [Therapeutic study of dimethyl-chlortetracycline (D.M.C.T.) in the form of drinkable suspensions, drops and tablets in pediatrics]. | 1962 | Med Interna (Bucur) | pmid:13868176 |
BRUEGGEMANN J et al. | [How do albino rats react to the long-term feeding of chicken meat that was pretreated with chlortetracycline? Generation studies on rats]. | 1961 | Arzneimittelforschung | pmid:13873878 |
BULDAKOVA GE | [Treatment of infected wounds by electrophoresis of antibiotics in experimental conditions]. | 1962 | Orv Hetil | pmid:13874584 |
CANCRINI A | [Experimental and clinical results of D.M.C.T. (demethylchlortetracycline) in infections of the urinary tract]. | 1961 | Ann Ital Chir | pmid:13876152 |
CHARPIN R and BOUTIN C | [Demethylchlortetracycline or RP 10,192 in respiratory pathology. Apropos of 50 observations]. | 1962 | Poumon Coeur | pmid:13878335 |
CHOPRA DR | Clinical trial with demethyl chlortetracycline in paediatric practice. | 1961 | Burma Med J | pmid:13879166 |
COZZA HG | [1st clinical trials in dermatology of demethylchlortetracycline]. | 1961 Sep-Oct | G Ital Dermatol | pmid:13881929 |
CUVELIER R et al. | [Contribution to the study of D.M.C.T. (demethylchlorotetracycline)]. | 1962 | Gaz Med Fr | pmid:13882835 |
DERGACHEV IS et al. | [Effect of chlortetracycline on the course of staphylococcal infection in experimental conditions]. | 1962 | Antibiotiki | pmid:13885583 |
DEVEBER LL | Photosensitivity, loosening of the nails, and discolouration of the nails and teeth in association with demethylchlortetracycline (Declomycin): report of a case, with review of other reported cases. | 1962 | Can Med Assoc J | pmid:13885871 |
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GABOR M | [Pseudo-glycosuria during tetracycline therapy]. | 1961 | Pol Tyg Lek | pmid:13896074 |
GILL E | [Demethylchlortetracycline]. | 1962 | Dtsch. Med. Wochenschr. | pmid:13898599 |
GOODMAN JJ and MATRISHIN M | Effect of sulfadiazine on the synthesis of demethylchlortetracycline by Streptomyces aureofaciens. | 1961 | J. Bacteriol. | pmid:13900314 |
GREWE JM and FELTS WJ | Effects of prior chlorotetracycline hydrochloride exposure on the behavior of subcutaneously implanted neonatal mouse humeri. | 1962 | Anat. Rec. | pmid:13901768 |
GRUPPER C and LIPSITCH L | [Onychopathy induced by demethylchlortetracycline]. | 1961 Nov-Dec | Bull Soc Fr Dermatol Syphiligr | pmid:13902467 |
HASLREITER E | [The therapy of chronic inflammatory diseases of the respiratory tract with an orally administered combination of tetracycline and chlortetracycline]. | 1961 | Arzneimittelforschung | pmid:13905243 |
HICKS JH | Demethylchloretracycline: a double-blind study in the treatment of acne with attention to side-effects noted. | 1962 | South. Med. J. | pmid:13907192 |
HITOMI K | [Studies on phosphorus metabolism in the kidney of albino rats under administration of antibiotics. II. Phosphorus metabolism in the kidney of albino rats under administration of aureomycin]. | 1962 | Paediatr Jpn | pmid:13907783 |
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SHER N | Hallucinations after chlorpromazine in an otosclerotic. | 1962 | Am J Psychiatry | pmid:13911692 |
SMITH MA et al. | A controlled trial of oral antibiotics in the treatment of acne vulgaris. | 1962 | Br. J. Dermatol. | pmid:13914345 |
TERSKIKH II and DZHUMANBAEVA AA | [Experimental and clinical studies on therapeutic effects of dibiomycin in trachoma]. | 1961 | Antibiotiki | pmid:13920383 |
THIVOLET J | [1st results obtained in humans by use of demethylchlortetracycline (DMCT), RP 10,192]. | 1962 | Sem Hop | pmid:13920719 |
TOSHKOV A et al. | [Chlortetracycline in experimental typhoid infection. I]. | 1961 | Izv Mikrobiol Inst (Sofiia) | pmid:13922091 |
TOSHKOV A and SHEIKOVA G | [Effect of chlortetracycline on the fixation activity of the reticuloendothelial system in mice. III]. | 1961 | Izv Mikrobiol Inst (Sofiia) | pmid:13922092 |
VILLANUEVA JR | Attempts to show inhibition of nitroreductase by aureomycin in cell-free extracts and isolation of an aureomycin-resistant Nocardia V. | 1962 | Nature | pmid:13926005 |
VOKAC C et al. | [The effect of chlortetracycline and neomycin on fat degradation in rats]. | 1961 | Dtsch Z Verdau Stoffwechselkr | pmid:13926547 |
KRONDL A et al. | [Digestion and absorption of fats]. | 1962 | Ceska Gynekol | pmid:13927033 |
KRYNSKI S and BECLA E | [Sensitivity of staphylococci, micrococci and sarcina to antibiotics]. | 1962 | Rev Fr Etud Clin Biol | pmid:13927178 |
LEUTS'KII KM and LIVKE TN | [Interaction of vitamin A and chlortetracycline in metabolism]. | 1963 | Ukr Biokhim Zh | pmid:13930003 |
LEVEILLE GA and SAUBERLICH HE | Influence of orally administered antibiotics on growth and plasma lipid levels of growing chicks. | 1963 | Rep US Army Med Res Nutr Lab Denver | pmid:13930034 |
MCWHORTER AC et al. | Resistance of salmonellae isolated in 1962 to chloretetracycline. | 1963 | Appl Microbiol | pmid:13932290 |
MAKAREVICH VG and LAZNIKOVA TN | [Some data on a comparative study of chlortetracycline-producing strains of Act. aureofaciens LSB-2201 and LSB-16]. | 1963 | Antibiotiki | pmid:13932307 |
MALEK P et al. | The proposed use of tetacycline antibiotics for the evaluation of the degree of burns. | 1963 | Acta Chir Plast | pmid:13932479 |
MALEK P et al. | Distribution and retention of tetracycline analogues in kidney tissue in some pathological conditions. | 1963 | J. Urol. | pmid:13932483 |
MALEK P et al. | Fluorescence of tetracycline analogues fixed in myocardial infarction. | 1963 | Cardiologia | pmid:13932484 |
MALVALDI V | [Antibiotic resistance and lysogenic power of S. paratyphi B]. | 1962 Nov-Dec | Riv Ist Sieroter Ital | pmid:13932649 |
MEYER KF | Antimicrobial therapy and prophylactic immunization in the control of psittacosis or Bedsonia infection in show birds. | 1962 | Schweiz Med Wochenschr | pmid:13935291 |
MEYERS E and SMITH DA | Microbiological degradation of tetracyclines. | 1962 | J. Bacteriol. | pmid:13935339 |
NIKOLOV T et al. | [Effect of chlortetracycline on the blood protein pattern in rabbits infected with Candida albicans]. | 1962 | Nauchni Tr Vissh Med Inst Sofiia | pmid:13938690 |
NIKOLOV T et al. | [Protein pattern in the blood serum of rabbits treated with chlortetracycline]. | 1962 | Nauchni Tr Vissh Med Inst Sofiia | pmid:13938691 |