chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Gatsonis CD and Ageloudis CA | Quantitative determination of antibiotics by means of densitometry on TLC. Part 2: Determination of tetracyclines. | 1982 | Pharmazie | pmid:7146072 |
White JR and Pearce FL | Characterization of chlortetracycline (aureomycin) as a calcium ionophore. | 1982 | Biochemistry | pmid:7150561 |
Obara K and Yabu H | Effects of caffeine on contraction and chlorotetracycline fluorescence in isolated single smooth muscle cells of guinea pig taenia coli. | 1982 | Jpn. J. Physiol. | pmid:7169694 |
Bradley BD et al. | Comparative pharmacokinetics of chlortetracycline in milk-fed versus conventionally fed calves. | 1982 | J. Vet. Pharmacol. Ther. | pmid:7183795 |
Krishnan H et al. | Effect of temperature acclimatisation of cockroaches on the binding of Ca2+ & Mg2+ to the coxal muscle mitochondria as visualised by fluorescent probe chlorotetracycline. | 1982 | Indian J. Biochem. Biophys. | pmid:7184864 |
Raynaud JP et al. | A swine dysentery model for evaluation of drug prophylaxis: efficacy of various drugs in the control of swine dysentery. | 1981 | Am. J. Vet. Res. | pmid:7224318 |
Mürer EH et al. | Effect of three calcium antagonists on platelet secretion and metabolism. | 1981 | Biochem. Pharmacol. | pmid:7225147 |
Lisovskaia IL | [Reversible inhibition of thrombocyte physiology by tetracycline derivatives]. | 1981 | Biull Eksp Biol Med | pmid:7260378 |
Clary BD et al. | The potentiation effect of citric acid in aureomycin in turkeys. | 1981 | Poult. Sci. | pmid:7267555 |
Kovalev VF et al. | [Biological equivalence study of chlortetracycline preparations used in veterinary medicine]. | 1981 | Antibiotiki | pmid:7271257 |
Wolniak SM et al. | The coincident distribution of calcium-rich membranes and kinetochore fibers at metaphase in living endosperm cells of Haemanthus. | 1981 | Eur. J. Cell Biol. | pmid:7285950 |
Pozin EIa et al. | [Intracellular calcium redistribution in the thrombocytes during aggregation and release reaction]. | 1981 | Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR | pmid:7317160 |
Lazarewicz JW et al. | Effect of barbiturates on calcium metabolism in rat brain synaptosomes visualized by chlorotetracycline as a fluorescent chelate probe. | 1981 | Cell Mol Biol Incl Cyto Enzymol | pmid:7317914 |
Waldroup PW et al. | Comparison of low dietary calcium and sodium sulfate for the potentiation of tetracycline antibiotics in broiler diets. | 1981 Oct-Dec | Avian Dis. | pmid:7337611 |
Pis'ko GT and Gudz' OV | [Effect of docecyl guanidine acetate on the in vitro activity of penicillin, streptomycin, levomycetin and chlortetracycline]. | 1980 | Antibiotiki | pmid:7356304 |
Mikkelsen RB and Schmidt-Ullrich R | Concanavalin A induces the release of intracellular Ca2+ in intact rabbit thymocytes. | 1980 | J. Biol. Chem. | pmid:7372631 |
O'Reilly PH et al. | Abacterial pyuria. | 1980 | Br J Radiol | pmid:7388288 |
Uchida M | Histamine-induced decrease of membrane-bound calcium ions in the membrane fraction of rabbit taenia coli. | 1980 | Eur. J. Pharmacol. | pmid:7389828 |
Nagasaki K and Kasai M | Magnesium permeability of sarcoplasmic reticulum vesicles monitored in terms of chlortetracycline fluorescence. | 1980 | J. Biochem. | pmid:7390959 |
MacInnes DG et al. | Detection of diamagnetic cation in tissue using the fluorescent probe chlortetracycline [proceedings]. | 1980 | Biochem. Soc. Trans. | pmid:7399083 |
Muhammad N and Bodnar JA | Separation and quantitation of chlortetracycline, 4-epitetracycline, 4-epianhydrotetracycline, and anhydrotetracycline in tetracycline by high-performance liquid chromatography. | 1980 | J Pharm Sci | pmid:7400938 |
Kudymov VM et al. | [Changes in the immunoreactivity of rats under the action of heat-treated chlortetracycline]. | 1980 | Gig Sanit | pmid:7409488 |
Wolniak SM et al. | Detection of the membrane-calcium distribution during mitosis in Haemanthus endosperm with chlorotetracycline. | 1980 | J. Cell Biol. | pmid:7419592 |
Terho P | Treatment of Chlamydia-positive and Chlamydia-negative nonspecific and postgonococcal urethritis. | 1978 | Ann. Clin. Res. | pmid:742827 |
Luthra R and Olson MS | The effects of chlorotetracycline on calcium movements in isolated rat liver mitochondria. | 1978 | Arch. Biochem. Biophys. | pmid:742885 |
Ragheb HS | Some factors affecting assay variability in the determination of chlortetracycline in premix feeds. | 1980 | J Assoc Off Anal Chem | pmid:7430030 |
Clark LK | Coccidiosis in baby pigs. | 1980 | Mod Vet Pract | pmid:7432341 |
Gains N | The limitations of chlorotetracycline as a fluorescent probe of divalent cations associated with membranes. | 1980 | Eur. J. Biochem. | pmid:7439184 |
Rummer HJ and Elze K | [Control of puerperium in swine under conditions of extremely shortened nursing method. 1. Results of histological studies in postpartum involution and regeneration of the uterus under conditions of extremely shortened nursing period and medicamentous control of puerperium]. | 1980 | Arch Exp Veterinarmed | pmid:7447598 |
Sharma JP and Bevill RF | Improved high-performance liquid chromatographic procedure for the determination of tetracyclines in plasma, urine and tissues. | 1978 | J. Chromatogr. | pmid:744780 |
Gawlitta W et al. | Pinocytosis and locomotion of amoebae. XV. Visualization of Ca++-dynamics by chlorotetracycline (CTC) fluorescence during induced pinocytosis in living Amoeba proteus. | 1980 | Cell Tissue Res. | pmid:7459998 |
Wang WH et al. | Functional analysis using chlortetracycline fluorescence and in vitro fertilization of frozen-thawed ejaculated boar spermatozoa incubated in a protein-free chemically defined medium. | 1995 | J. Reprod. Fertil. | pmid:7473423 |
Kay VJ et al. | Effects of pentoxifylline and progesterone on human sperm capacitation and acrosome reaction. | 1994 | Hum. Reprod. | pmid:7536212 |
Perry RL et al. | A time course study of capacitation and the acrosome reaction in human spermatozoa using a revised chlortetracycline pattern classification. | 1995 | Fertil. Steril. | pmid:7540564 |
McEvoy JD et al. | Influence of environmental contamination of a pig unit on chlortetracycline residues in pig tissues. | 1995 | Vet. Rec. | pmid:7571266 |
Gallo GF and Berg JL | Efficacy of a feed-additive antibacterial combination for improving feedlot cattle performance and health. | 1995 | Can. Vet. J. | pmid:7600512 |
Naccache PH et al. | Chemotactic factor-induced release of membrane calcium in rabbit neutrophils. | 1979 | Science | pmid:760200 |
Kremneva LV et al. | [Intracellular homeostasis and membrane permeability for calcium in essential hypertension]. | 1995 Mar-Apr | Klin. Lab. Diagn. | pmid:7620791 |
Savin JA | International mortality from bullous diseases since 1950. | 1976 | Br. J. Dermatol. | pmid:766815 |
Dairi T et al. | Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains. | 1995 | Biosci. Biotechnol. Biochem. | pmid:7670200 |
Ellington JE et al. | Binding of stallion spermatozoa to the equine zona pellucida after coculture with oviductal epithelial cells. | 1993 | J. Reprod. Fertil. | pmid:7688425 |
Nguyen-Van-Ai et al. | [Bacteriological and epidemiological considerations on shigelloses in South Vietnam (1969-1973)]. | 1975 May-Jun | Bull Soc Pathol Exot Filiales | pmid:770024 |
Kiser JS | A perspective on the use of antibiotics in animal feeds. | 1976 | J. Anim. Sci. | pmid:770412 |
Kisker C et al. | The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance. | 1995 | J. Mol. Biol. | pmid:7707374 |
Shi QX and Roldan ER | Bicarbonate/CO2 is not required for zona pellucida- or progesterone-induced acrosomal exocytosis of mouse spermatozoa but is essential for capacitation. | 1995 | Biol. Reprod. | pmid:7756449 |
Maxwell CV et al. | Effect of dietary chlortetracycline during breeding and(or) farrowing and lactation on reproductive performance of sows: a cooperative study. S-145 Committee on Nutritional Systems for Swine to Increase Reproductive Efficiency. | 1994 | J. Anim. Sci. | pmid:7759367 |
ZakrevskiÄ VI et al. | [Polyamines in microorganisms sensitive and resistant to antibiotics]. | 1976 | Antibiotiki | pmid:776080 |
Astarie-Dequeker C et al. | Endothelin-3 reduces Ca(2+)-uptake and Ca2+ content of platelet internal stores. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7763261 |
Fuska J et al. | Biotransformation of benzyl thiocyanate by Streptomyces aureofaciens. | 1994 | Lett. Appl. Microbiol. | pmid:7765389 |
Fraser LR et al. | Ca(2+)-regulating mechanisms that modulate bull sperm capacitation and acrosomal exocytosis as determined by chlortetracycline analysis. | 1995 | Mol. Reprod. Dev. | pmid:7766417 |
Dacasto M and Cocuzza U | Efficacy of chlortetracycline for controlling goat coccidiosis in Burundi. | 1994 | Rev Elev Med Vet Pays Trop | pmid:7770661 |
Ganter M et al. | [Treatment of swine with chronic pneumonia with chlortetracycline-medicated feed]. | 1995 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:7781539 |
Gutzmann F et al. | Influence of antibiotic-supplemented feed on occurrence and persistence of Salmonella typhimurium in experimentally infected swine. | 1976 | Am. J. Vet. Res. | pmid:779539 |
Tydel'skaia IL et al. | [Sensitivity to doxycycline (vibramycin) of the microflora isolated from the patients in a therapeutic clinic]. | 1975 | Antibiotiki | pmid:779626 |
Le Breton GC et al. | Direct evidence for intracellular divalent cation redistribution associated with platelet shape change. | 1976 | Biochem. Biophys. Res. Commun. | pmid:786285 |
Whitney JC | A review of non-specific enteritis in the rabbit. | 1976 | Lab. Anim. | pmid:787667 |
McEvoy JD et al. | Origin of chlortetracycline in pig tissue. | 1994 | Analyst | pmid:7879861 |
Ward JM et al. | A double-blind trial of clomocycline in the treatment of persistent palmoplantar pustulosis. | 1976 | Br. J. Dermatol. | pmid:788767 |
Collier GB et al. | A novel Tn10 tetracycline regulon system controlling expression of the bacteriophage T3 gene encoding S-adenosyl-L-methionine hydrolase. | 1994 | Gene | pmid:7926842 |
Häyrinen-Immonen R et al. | Effect of tetracyclines on collagenase activity in patients with recurrent aphthous ulcers. | 1994 | J. Oral Pathol. Med. | pmid:7932246 |
Nivas SC et al. | Effects of different levels of chlortetracycline in the diet of turkey poults artifically-infected with Salmonella typhimurium. | 1976 | Poult. Sci. | pmid:798179 |
Saran S et al. | The level of sequestered calcium in vegetative amoebae of Dictyostelium discoideum can predict post-aggregative cell fate. | 1994 | Differentiation | pmid:7988792 |
Pankhurst CL et al. | Prophylactic application of an intra-alveolar socket medicament to reduce postextraction complications in HIV-seropositive patients. | 1994 | Oral Surg. Oral Med. Oral Pathol. | pmid:8015795 |
Tasman AJ et al. | [Sclerosing lipogranulomatosis of the eyelids after ethmoid sinus surgery: a complication after ointment tamponade!]. | 1994 | Laryngorhinootologie | pmid:8018240 |
Furuya S et al. | Effect of epidermal growth factor on mouse sperm acrosome reaction induced by zona pellucida. | 1994 Mar-Apr | Am. J. Reprod. Immunol. | pmid:8049021 |
Beres L and Lucas-Lenard J | Studies on the in vitro synthesis of ppGpp and pppGpp. | 1975 | Biochim. Biophys. Acta | pmid:806304 |
Neidleman SL | Microbial halogenation. | 1975 | CRC Crit Rev Microbiol | pmid:806421 |
Olson LD et al. | Treatment of group E streptococci-induced lymphadenitis in swine by feeding various concentrations of chlortetracycline: relation of antibody with prevalence of abscesses. | 1994 | Am. J. Vet. Res. | pmid:8067612 |
MalÃková M et al. | [Residues of antimicrobial substances in the meat and organs of slaughter calves]. | 1975 | Vet Med (Praha) | pmid:807014 |
Tsai CE and Kondo F | Simple continuous and simultaneous determination of tetracycline residues. | 1994 | Res. Vet. Sci. | pmid:8073177 |
Inamoto T et al. | Antibiotic susceptibility of Mycoplasma hyopneumoniae isolated from swine. | 1994 | J. Vet. Med. Sci. | pmid:8075234 |
Furness G and Whitescarver J | Adaptation of Mycoplasma hominis to an obligate parasitic existence in monkey kidney cell culture (BSC-1). | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:807916 |
DomaradskiÄ IV | [Iridescent phenomenon in Pseudomonas aeruginosa]. | 1975 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:808057 |
Green CM et al. | Stimulating effect of pyroglutamylglutamylprolineamide, a prostatic, TRH-related tripeptide, on mouse sperm capacitation and fertilizing ability in vitro. | 1994 | Mol. Reprod. Dev. | pmid:8080651 |
Miyazaki S et al. | A comparison of bioavailability of free bases and hydrochloride salts of chlortetracycline, demethylchlortetracycline, and methacycline. | 1975 | Chem. Pharm. Bull. | pmid:810254 |
Slavchev G | [Influence of some factors on the quality of Bulgarian sour milk]. | 1975 | Vet Med Nauki | pmid:810941 |
Helmy N and Fowler W | Intensive and prolonged tetracycline therapy in non-specific urethritis. | 1975 | Br J Vener Dis | pmid:811319 |
Urbanová Z et al. | [Effect of tylosin in pigs]. | 1975 | Vet Med (Praha) | pmid:812238 |
Ragheb HS | Modified assay medium for the turbidimetric assay of chlortetracycline in feeds. | 1976 | J Assoc Off Anal Chem | pmid:818071 |
Tabakov VIu et al. | [Intergeneric Escherichia coli-Streptomyces conjugation as a means for the transfer of conjugative plasmids into producers of antibiotics chlortetracycline and bialaphos]. | 1994 | Genetika | pmid:8188047 |
Hostálek Z et al. | Role of ATP-glucokinase and polyphosphate glucokinase in Streptomyces aureofaciens. | 1976 | Folia Microbiol. (Praha) | pmid:820617 |
Nikitin VP et al. | Mechanisms of the development of sensitizations in the snail: the participation of calcium and calmodulin. | 1994 Jan-Feb | Neurosci. Behav. Physiol. | pmid:8208373 |
Luthra R and Olson MS | Studies of mitochondrial calcium movements using chlorotetracycline. | 1976 | Biochim. Biophys. Acta | pmid:822874 |
Gilio VE and Cilento G | Light emission accompanies oxygen uptake during the peroxidative metabolism of tetracyclines. | 1993 | Photochem. Photobiol. | pmid:8234480 |
Curdová E et al. | Regulation and biosynthesis of secondary metabolites. XVIII. Adenylate level and chlorotetracycline production in Streptomyces aureofaciens. | 1976 | Folia Microbiol. (Praha) | pmid:825418 |
Varner DD et al. | Effect of heparin on capacitation/acrosome reaction of equine sperm. | 1993 Nov-Dec | Arch. Androl. | pmid:8274046 |
DasGupta S et al. | Ca(2+)-related changes in the capacitation state of human spermatozoa assessed by a chlortetracycline fluorescence assay. | 1993 | J. Reprod. Fertil. | pmid:8283430 |
Adeoya-Osiguwa SA and Fraser LR | A biphasic pattern of 45Ca2+ uptake by mouse spermatozoa in vitro correlates with changing functional potential. | 1993 | J. Reprod. Fertil. | pmid:8283437 |
Compendium of chlamydiosis (psittacosis) control, 1994. National Association of State Public Health Veterinarians Inc. | 1993 | J. Am. Vet. Med. Assoc. | pmid:8307816 | |
White CR et al. | Optimization of a liquid chromatographic method for determination of oxytetracycline, tetracycline, and chlortetracycline in milk. | 1993 May-Jun | J AOAC Int | pmid:8318847 |
Strelis AK et al. | [The significance of cytochemical studies of the metals in blood neutrophilic granulocytes in the diagnosis of lung diseases]. | 1993 | Lik. Sprava | pmid:8379137 |
Furuya S et al. | Calyculin A, protein phosphatase inhibitor, enhances capacitation of human sperm. | 1993 | Fertil. Steril. | pmid:8380391 |
Zinn RA | Influence of oral antibiotics on digestive function in Holstein steers fed a 71% concentrate diet. | 1993 | J. Anim. Sci. | pmid:8384195 |
Roevens P and de Chaffoy de Courcelles D | Cyclic AMP-phosphodiesterase IIIA1 inhibitors decrease cytosolic Ca2+ concentration and increase the Ca2+ content of intracellular storage sites in human platelets. | 1993 | Biochem. Pharmacol. | pmid:8390836 |
Daniel MA et al. | Defective chemotaxis and calcium response in localized juvenile periodontitis neutrophils. | 1993 | J. Periodontol. | pmid:8396175 |
Suichies HR et al. | [Dermatitis digitalis? Considerations in the evaluation of an intensive therapy]. | 1993 | Tijdschr Diergeneeskd | pmid:8434367 |
Zimmermann M and Preac-Mursic V | The antimicrobial actions of taurolin and other preparations on the pathogenic spectrum in dentoalveolar infections. | 1993 | Int J Clin Pharmacol Ther Toxicol | pmid:8468110 |
Labza D and Janik B | [Use of cerium salts (III) in the spectrophotometric determination of chlorotetracycline]. | 1977 | Acta Pol Pharm | pmid:848323 |
Browning DD et al. | Comparative analysis of chemotaxis in Dictyostelium using a radial bioassay method: protein tyrosine kinase activity is required for chemotaxis to folate but not to cAMP. | 1995 | Cell. Signal. | pmid:8562309 |
Matsushita S and Suzuki E | Prevention and treatment of cilia-associated respiratory bacillus in mice by use of antibiotics. | 1995 | Lab. Anim. Sci. | pmid:8569147 |