chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Trostle SS et al. | Use of antimicrobial-impregnated polymethyl methacrylate beads for treatment of chronic, refractory septic arthritis and osteomyelitis of the digit in a bull. | 1996 | J. Am. Vet. Med. Assoc. | pmid:8575974 |
Fraser LR et al. | Fertilization--calcium-dependent events. | 1996 | Fertil. Steril. | pmid:8641514 |
Olson LD | Comparison of low-level rofenaid, low-level chlortetracycline, and vaccination with commercial bacterin for preventing pulmonary form of fowl cholera in turkeys. | 1977 Apr-Jun | Avian Dis. | pmid:869823 |
Korsrud GO et al. | Residue depletion in tissues and fluids from swine fed sulfamethazine, chlortetracycline and penicillin G in combination. | 1996 | Food Addit Contam | pmid:8718743 |
Le Grand A and Kobisch M | [Comparison of the use of a vaccine and sequential antibiotic treatment in a herd infected with Mycoplasma hyopneumoniae]. | 1996 | Vet. Res. | pmid:8767886 |
Heyden YV et al. | Ruggedness tests on the high performance liquid chromatography assay of the United States Pharmacopoeia 23 for tetracycline.HCl: comparison of different columns in an interlaboratory approach. | 1996 | J Pharm Biomed Anal | pmid:8818050 |
Hathaway MR et al. | Serum insulin-like growth factor I (IGF-I) concentrations are increased in pigs fed antimicrobials. | 1996 | J. Anim. Sci. | pmid:8818798 |
Sbracia M et al. | Sperm function and choice of preparation media: comparison of Percoll and Accudenz discontinuous density gradients. | 1996 Jan-Feb | J. Androl. | pmid:8833742 |
Popova GO et al. | [Effect of several antibiotics and their combination with prodigiozan on Y. pestis EV, engulfed by macrophages]. | 1977 | Antibiotiki | pmid:883789 |
Carvalho CA and Carvalho AP | Fluorimetric monitoring of calcium binding to sarcoplasmic reticulum membranes. | 1977 | Biochim. Biophys. Acta | pmid:884082 |
Behymer D et al. | Observation on chemotherapy in cows chronically infected with Coxiella burnetii (Q fever). | 1977 Jan-Mar | Folia Vet Lat | pmid:885444 |
Nielsen P and Gyrd-Hansen N | Bioavailability of oxytetracycline, tetracycline and chlortetracycline after oral administration to fed and fasted pigs. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8866460 |
Ridgway GL and Oriel JD | Treatment of neonatal inclusion blennorrhea. | 1977 | N. Engl. J. Med. | pmid:887138 |
van Pée KH | Biosynthesis of halogenated metabolites by bacteria. | 1996 | Annu. Rev. Microbiol. | pmid:8905085 |
Markakis PK | Determination of tetracyclines in animal feeds in the presence of other drugs by thin-layer chromatography and microbiological method. | 1996 Mar-Apr | J AOAC Int | pmid:8920124 |
MacNeil JD et al. | Chlortetracycline, oxytetracycline, and tetracycline in edible animal tissues, liquid chromatographic method: collaborative study. | 1996 Mar-Apr | J AOAC Int | pmid:8920127 |
Wyatt PJ et al. | Laser light scattering bioassay for veterinary drug residues in food producing animals. 2. Preparation procedures and dose-response studies of drugs in bovine tissues. | 1977 Sep-Oct | J. Agric. Food Chem. | pmid:893831 |
Stubbings G et al. | On-line metal chelate affinity chromatography clean-up for the high-performance liquid chromatographic determination of tetracycline antibiotics in animal tissues. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8998553 |
Kupferman A and Leibowitz HM | Topical antibiotic therapy of staphylococcal keratitis. | 1977 | Arch. Ophthalmol. | pmid:901273 |
Nishimura M et al. | Pharmacologic inhibition of twin-pulse facilitation of release of transmitter quanta at the mouse neuromuscular junction. | 1997 | Gen. Pharmacol. | pmid:9013215 |
Sharma JP et al. | High-pressure liquid chromatographic determination of tetracyclines in urine. | 1977 | J Pharm Sci | pmid:903874 |
Maxwell WM and Johnson LA | Chlortetracycline analysis of boar spermatozoa after incubation, flow cytometric sorting, cooling, or cryopreservation. | 1997 | Mol. Reprod. Dev. | pmid:9041145 |
Henderson JP et al. | Anaemia and low viability in piglets infected with Eperythrozoon suis. | 1997 | Vet. Rec. | pmid:9050175 |
de las Heras MA et al. | In vitro capacitating effect of gamma-aminobutyric acid in ram spermatozoa. | 1997 | Biol. Reprod. | pmid:9096879 |
Oka H et al. | Improvement of chemical analysis of antibiotics. XXIII. Identification of residual tetracyclines in bovine tissues by electrospray high-performance liquid chromatography-tandem mass spectrometry. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9210437 |
Lavrinchuk VIa et al. | [The induction of mutations in Streptomyces aureofaciens by UV rays and nitrosoguanidine and the identification of the mutants obtained]. | 1997 Mar-Apr | Mikrobiol. Z. | pmid:9221058 |
Sukocheva OA et al. | In vitro effect of hydrocortisone on calcium distribution in rat thymocytes. | 1997 | Membr Cell Biol | pmid:9231360 |
Residues of some veterinary drugs in animals and foods. Joint FAO/WHO Expert Committee on Food Additives. | 1996 | FAO Food Nutr Pap | pmid:9237075 | |
Murray SC and Smith TT | Sperm interaction with fallopian tube apical membrane enhances sperm motility and delays capacitation. | 1997 | Fertil. Steril. | pmid:9240269 |
Al-Mohanna FA et al. | Does actin polymerization status modulate Ca2+ storage in human neutrophils? Release and coalescence of Ca2+ stores by cytochalasins. | 1997 | Exp. Cell Res. | pmid:9260908 |
Abeydeera LR et al. | Chlortetracycline fluorescence patterns and in vitro fertilisation of frozen-thawed boar spermatozoa incubated under various bicarbonate concentrations. | 1997 | Zygote | pmid:9276509 |
Yang J et al. | Study on the fluorescence system of chlortetracycline-Eu-TOPO-sodium dodecyl sulfonate and the determination of chlortetracycline. | 1997 | J Pharm Biomed Anal | pmid:9278887 |
Ward KL | Serum chlortetracycline concentrations in parrots fed mediated seed diets. | 1997 | Aust. Vet. J. | pmid:9293334 |
Blackman HJ et al. | Antibiotic susceptibility of Chlamydia trachomatis. | 1977 | Antimicrob. Agents Chemother. | pmid:931365 |
Asanza Teruel ML et al. | Response surface analysis of chlortetracycline and tetracycline production with K-carrageenan immobilized Streptomyces aureofaciens. | 1997 | Enzyme Microb. Technol. | pmid:9322372 |
McCallon BR | Anaplasmosis. | 1976 | J. Dairy Sci. | pmid:932259 |
Kotzias-Bandeira E et al. | [Cooling of boar spermatozoa prior to freezing and post thaw quality and evaluation of membrane state using chlortetracycline (CTC) staining]. | 1997 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:9324457 |
Houglum JE et al. | Assay of chlortetracycline in animal feeds by liquid chromatography with fluorescence detection. | 1997 Sep-Oct | J AOAC Int | pmid:9325574 |
Ohe O and Arakawa A | Effect of dietary antibiotics on chickens infected with Eimeria tenella. | 1976 | Poult. Sci. | pmid:935023 |
Kaul G et al. | Calcium requirement and time course of capacitation of goat spermatozoa assessed by chlortetracycline assay. | 1997 Sep-Oct | Andrologia | pmid:9350324 |
Onawunmi OA and Todd AC | Suppression and control of experimentally induced procine coccidiosis with chlortetracycline combination, buquinolate, and lincomycin hydrochloride. | 1976 | Am. J. Vet. Res. | pmid:937785 |
Perry RL et al. | Response of human spermatozoa to an internal calcium ATPase inhibitor, 2,5-di(tert-butyl) hydroquinone. | 1997 | J. Exp. Zool. | pmid:9379154 |
Olson NO and Sahu SP | Efficacy of chlortetracycline against Mycoplasma synoviae isolated in two periods. | 1976 Apr-Jun | Avian Dis. | pmid:938371 |
Hashimoto I et al. | Epidermolysis bullosa hereditaria with junctional blistering in an adult. | 1976 | Dermatologica | pmid:939338 |
Pettit EJ and Hallett MB | Two distinct Ca2+ storage and release sites in human neutrophils. | 1998 | J. Leukoc. Biol. | pmid:9468281 |
Kazemifard AG and Moore DE | Evaluation of amperometric detection for the liquid-chromatographic determination of tetracycline antibiotics and their common contaminants in pharmaceutical formulations. | 1997 | J Pharm Biomed Anal | pmid:9502164 |
Akota I et al. | The effect of locally applied gauze drain impregnated with chlortetracycline ointment in mandibular third-molar surgery. | 1998 | Acta Odontol. Scand. | pmid:9537731 |
Simon N and Dobozy A | Effect of hydrocortisone 17-butyrate on the percutaneous absorption of antibiotics. | 1976 | Dermatologica | pmid:955236 |
Shakarian GA and Sevian TK | [Chlortetracycline concentration in the tissues of fish]. | 1976 | Veterinariia | pmid:960526 |
Minoprio JL et al. | [Current problems in the treatment of human brucellosis]. | 1976 | Clin Ter | pmid:963961 |
Stezowski JJ | Chemical-structural properties of tetracycline derivatives. 1. Molecular structure and conformation of the free base derivatives. | 1976 | J. Am. Chem. Soc. | pmid:965636 |
Gill BS et al. | Immunisation against bovine tropical theileriasis (Theileria annulata infection). | 1976 | Res. Vet. Sci. | pmid:968181 |
Beharka AA and Nagaraja TG | Effect of Aspergillus oryzae extract alone or in combination with antimicrobial compounds on ruminal bacteria. | 1998 | J. Dairy Sci. | pmid:9684165 |
Hewitt DA and England GC | An investigation of capacitation and the acrosome reaction in dog spermatozoa using a dual fluorescent staining technique. | 1998 | Anim. Reprod. Sci. | pmid:9686314 |
Kennedy DG et al. | Iso- and epi-iso-chlortetracycline and the principal metabolites of chlortetracycline in the hen's egg. | 1998 | J Chromatogr A | pmid:9691329 |
Honikel KO and Hambloch H | [Fast fluorimetric assay of chlortetracycline in meat and bone (author's transl)]. | 1976 | Z Lebensm Unters Forsch | pmid:969905 |
Dehpour AR et al. | Calcium release by diltiazem from isolated sarcoplasmic reticulum of rabbit skeletal muscle. | 1998 | Gen. Pharmacol. | pmid:9703221 |
Semjén G et al. | Therapeutic efficacy of doxycycline against experimental Pasteurella multocida infection in broiler chickens. | 1998 | Acta Vet. Hung. | pmid:9704513 |
Langlois BE et al. | Influence of type of antibiotic and length of antibiotic feeding period on performance and persistence of antibiotic resistant enteric bacteria in growing-finishing swine. | 1978 | J. Anim. Sci. | pmid:97254 |
Lundgren T and Linde A | Modulation of rat incisor odontoblast plasma membrane-associated Ca2+ with nifedipine. | 1998 | Biochim. Biophys. Acta | pmid:9733994 |
Miyazaki S et al. | Polymorphic transformation of chlortetracycline hydrochloride crystals studied by infrared spectrophotometric method. | 1976 | Chem. Pharm. Bull. | pmid:975438 |
Mortimer ST et al. | Effect of seminal plasma on capacitation and hyperactivation in human spermatozoa. | 1998 | Hum. Reprod. | pmid:9756285 |
Peterson RN and Freund M | Relationship between motility and the transport and binding of divalent cations to the plasma membrane of human spermatozoa. | 1976 | Fertil. Steril. | pmid:976503 |
Nouws JF et al. | Testing of raw milk for tetracycline residues. | 1998 | J. Dairy Sci. | pmid:9785224 |
Couppié P et al. | [Impetigo in French Guyana. A clinical, bacteriological, toxicological and sensitivity to antibiotics study]. | 1998 | Ann Dermatol Venereol | pmid:9835957 |
Maladkar NK and Deshpande VN | Effect of L-aromatic amino acids on biosynthesis of chlortetracycline by washed resting cells of Streptomyces aureofaciens. | 1978 | Indian J. Exp. Biol. | pmid:98433 |
Ajayi JA | Effects of Aureo-S-700R on sporulation, viability and infectivity of ovine coccidial oocysts. | 1976 | Parasitology | pmid:987566 |
Couto CM et al. | Tetracycline, oxytetracycline and chlortetracycline determination by flow injection potentiometry. | 1998 | J Pharm Biomed Anal | pmid:9919952 |
Nurazian AG | [Penetration, distribution and retention of chlortetracycline in the body of pregnant rabbits and their fetuses]. | 1976 | Antibiotiki | pmid:999254 |