chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Keston AS et al. | Detection of ocular melanoma in rabbits, using anhydrotetracycline fluorescence. | 1967 | Am. J. Ophthalmol. | pmid:6036301 |
CLARK SG and CULLER AM | Aureomycin as prophylaxis against ophthalmia neonatorum. | 1951 | Am. J. Ophthalmol. | pmid:14838060 |
FURTH FW et al. | The effect of aureomycin and terramycin on the X-radiated rat. | 1952 Mar-Apr | Am. J. Pathol. | pmid:14903050 |
FURTH FW et al. | Bacteriologic studies of the X-radiated dog. | 1952 Mar-Apr | Am. J. Pathol. | pmid:14903049 |
FURTH FW et al. | The effect of aureomycin on the radiation syndrome in dogs. | 1952 Jan-Feb | Am. J. Pathol. | pmid:14885404 |
Gleva GF et al. | Altered calcium homeostasis in irreversibly injured P388D1 macrophages. | 1990 | Am. J. Pathol. | pmid:2164776 |
Adamson IY et al. | A pathway to pulmonary fibrosis: an ultrastructural study of mouse and rat following radiation to the whole body and hemithorax. | 1970 | Am. J. Pathol. | pmid:5436095 |
DeFeo TT et al. | Ca2+ signals obtained with multiple indicators in mammalian vascular muscle cells. | 1987 | Am. J. Physiol. | pmid:3425745 |
Brace LD et al. | Reversal of thromboxane A2/prostaglandin H2 and ADP-induced calcium release in intact platelets. | 1985 | Am. J. Physiol. | pmid:2409821 |
Brace LD et al. | Thromboxane A2/prostaglandin H2 mobilizes calcium in human blood platelets. | 1985 | Am. J. Physiol. | pmid:3925795 |
Burch RM and Halushka PV | ADH or theophylline-induced changes in intracellular free and membrane-bound calcium. | 1984 | Am. J. Physiol. | pmid:6439053 |
LEE HW and MOINUDDIN JF | Effects of oral chlortetracycline on diarrhea and on the dry weights of cleaned intestinal organs in rats fed two different diets. | 1958 | Am. J. Physiol. | pmid:13508894 |
ZIMMERMAN HJ and HUMOLLER FL | Effect of aureomycin on choline oxidase and other enzyme systems of rat liver. | 1953 | Am. J. Physiol. | pmid:13114430 |
FRANK HA et al. | Traumatic shock. XXI. Effectiveness of an antibiotic in experimental hemorrhagic shock. | 1952 | Am. J. Physiol. | pmid:14903159 |
INNERFIELD I et al. | Effect of aureomycin upon blood coagulation time, Ac-globulin and prothrombin activity. | 1951 | Am. J. Physiol. | pmid:14885446 |
Owen NE and Le Breton GC | Ca2+ mobilization in blood platelets as visualized by chlortetracycline fluorescence. | 1981 | Am. J. Physiol. | pmid:6274207 |
BANASZAK EF et al. | Comparative effect of heparin and other agents on traumatic shock in the rat. | 1959 | Am. J. Physiol. | pmid:13796360 |
Lanman RC et al. | Hepatic uptake and biliary excretion of tetracycline in the rat. | 1973 | Am. J. Physiol. | pmid:4745227 |
COLBY RW et al. | Effect of feeding an 'animal protein factor' concentrate to young lambs. | 1950 | Am. J. Physiol. | pmid:14790012 |
Gershengorn MC and Thaw C | TRH mobilizes membrane calcium in thyrotropic cells as monitored by chlortetracycline. | 1982 | Am. J. Physiol. | pmid:6812433 |