chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Hostálek Z et al. | Role of ATP-glucokinase and polyphosphate glucokinase in Streptomyces aureofaciens. | 1976 | Folia Microbiol. (Praha) | pmid:820617 |
Nikitin VP et al. | Mechanisms of the development of sensitizations in the snail: the participation of calcium and calmodulin. | 1994 Jan-Feb | Neurosci. Behav. Physiol. | pmid:8208373 |
Luthra R and Olson MS | Studies of mitochondrial calcium movements using chlorotetracycline. | 1976 | Biochim. Biophys. Acta | pmid:822874 |
Gilio VE and Cilento G | Light emission accompanies oxygen uptake during the peroxidative metabolism of tetracyclines. | 1993 | Photochem. Photobiol. | pmid:8234480 |
Curdová E et al. | Regulation and biosynthesis of secondary metabolites. XVIII. Adenylate level and chlorotetracycline production in Streptomyces aureofaciens. | 1976 | Folia Microbiol. (Praha) | pmid:825418 |
Varner DD et al. | Effect of heparin on capacitation/acrosome reaction of equine sperm. | 1993 Nov-Dec | Arch. Androl. | pmid:8274046 |
DasGupta S et al. | Ca(2+)-related changes in the capacitation state of human spermatozoa assessed by a chlortetracycline fluorescence assay. | 1993 | J. Reprod. Fertil. | pmid:8283430 |
Adeoya-Osiguwa SA and Fraser LR | A biphasic pattern of 45Ca2+ uptake by mouse spermatozoa in vitro correlates with changing functional potential. | 1993 | J. Reprod. Fertil. | pmid:8283437 |
Compendium of chlamydiosis (psittacosis) control, 1994. National Association of State Public Health Veterinarians Inc. | 1993 | J. Am. Vet. Med. Assoc. | pmid:8307816 | |
White CR et al. | Optimization of a liquid chromatographic method for determination of oxytetracycline, tetracycline, and chlortetracycline in milk. | 1993 May-Jun | J AOAC Int | pmid:8318847 |
Strelis AK et al. | [The significance of cytochemical studies of the metals in blood neutrophilic granulocytes in the diagnosis of lung diseases]. | 1993 | Lik. Sprava | pmid:8379137 |
Furuya S et al. | Calyculin A, protein phosphatase inhibitor, enhances capacitation of human sperm. | 1993 | Fertil. Steril. | pmid:8380391 |
Zinn RA | Influence of oral antibiotics on digestive function in Holstein steers fed a 71% concentrate diet. | 1993 | J. Anim. Sci. | pmid:8384195 |
Roevens P and de Chaffoy de Courcelles D | Cyclic AMP-phosphodiesterase IIIA1 inhibitors decrease cytosolic Ca2+ concentration and increase the Ca2+ content of intracellular storage sites in human platelets. | 1993 | Biochem. Pharmacol. | pmid:8390836 |
Daniel MA et al. | Defective chemotaxis and calcium response in localized juvenile periodontitis neutrophils. | 1993 | J. Periodontol. | pmid:8396175 |
Suichies HR et al. | [Dermatitis digitalis? Considerations in the evaluation of an intensive therapy]. | 1993 | Tijdschr Diergeneeskd | pmid:8434367 |
Zimmermann M and Preac-Mursic V | The antimicrobial actions of taurolin and other preparations on the pathogenic spectrum in dentoalveolar infections. | 1993 | Int J Clin Pharmacol Ther Toxicol | pmid:8468110 |
Labza D and Janik B | [Use of cerium salts (III) in the spectrophotometric determination of chlorotetracycline]. | 1977 | Acta Pol Pharm | pmid:848323 |
Browning DD et al. | Comparative analysis of chemotaxis in Dictyostelium using a radial bioassay method: protein tyrosine kinase activity is required for chemotaxis to folate but not to cAMP. | 1995 | Cell. Signal. | pmid:8562309 |
Matsushita S and Suzuki E | Prevention and treatment of cilia-associated respiratory bacillus in mice by use of antibiotics. | 1995 | Lab. Anim. Sci. | pmid:8569147 |